Allele Dmel\Gad1^unspecified

General Information
Symbol	Dmel\Gad1^unspecified	Species	D. melanogaster
Name		FlyBase ID	FBal0049820
Feature type	allele	Associated gene	Dmel\Gad1

Allele class
Mutagen
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class
Mutagen
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Cytology
Phenotypic Data
Phenotypic Class
	lethal \| recessive (Harrison et al., 1995)
Phenotype Manifest In

Detailed Description
	Statement Reference Homozygous Gad1 mutant embryos removed manually from the egg are, like the few larvae that hatch, severely unco-odinated and contract their entire body in response to touch rather than initiating typical peristaltic "crawling" movements. Gross morphology of mutants is completely normal, with no defects visible. Muscle shape, patterning, and innervation are normal the gut and segmental patterning of the epidermis and denticle belts appear normal, and the central nervous system appears normally formed. At 22-24 hours after egg laying, trachea are inflated. (Featherstone et al., 2000)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

Comments
	Eighteen alleles have been isolated. (Harrison et al., 1995)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	Gad1^unspecified l(3)64An^unspecified unspecified (Harrison et al., 1995)
Name Synonym
Secondary FlyBase IDs

References ( 2 )
Research paper	Featherstone et al., 2000, Neuron 27(1): 71--84 Presynaptic glutamic acid decarboxylase is required for induction of the postsynaptic receptor field at a glutamatergic synapse. [FBrf0130303] Harrison et al., 1995, Genetics 139(4): 1701--1709 A genetic analysis of the 63E-64A genomic region of Drosophila melanogaster: Identification of mutations in a replication factor C subunit. [FBrf0080079]

Allele Dmel\Gad1unspecified

Allele Dmel\Gad1^unspecified