Allele Ecol\lacZ^Fmrf.WF3

General Information
Symbol	Ecol\lacZ^Fmrf.WF3	Species	E. coli
Name		FlyBase ID	FBal0049909
Feature type	allele	Associated gene	Ecol\lacZ

Allele class
Mutagen	in vitro construct - regulatory fusion
Recent Updates
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - regulatory fusion (Schneider et al., 1993)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype	Ecol\lacZ^C4.Adh (Schneider et al., 1993)
Nature of the lesion	Statement Reference Construct: 8kb fragment of Fmrf from -5000bp to amino acid 23 of exon 2 (containing 5kb upstream sequence, exon I, the entire intron and 69bp of exon II) fused in frame drives the expression of Ecol\lacZ^C4.Adh. (Schneider et al., 1993)
Carried in construct	P{WF3} (Schneider et al., 1993, Allan et al., 2003, Taghert et al., 2000, Benveniste et al., 1998, Benveniste and Taghert, 1999, Miguel-Aliaga et al., 2004, Allan et al., 2003, Kolhekar et al., 1997)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In

Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

Comments
	Ecol\lacZ expression closely resembles the endogenous pattern of Fmrf gene expression. (Schneider et al., 1993)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Ecol\lacZ^Fmrf.WF3 lacZ^Fmrf.WF3
Name Synonym
Secondary FlyBase IDs

References ( 8 )
Research paper	Miguel-Aliaga et al., 2004, Development 131(23): 5837--5848 Independent roles of the dachshund and eyes absent genes in BMP signaling, axon pathfinding and neuronal specification. [FBrf0180178] Allan et al., 2003, Cell 113(1): 73--86 Specification of neuropeptide cell identity by the integration of retrograde BMP signaling and a combinatorial transcription factor code. [FBrf0158766] Taghert et al., 2000, Dev. Biol. 222(2): 471--485 Metamorphosis of tangential visual system neurons in Drosophila. [FBrf0128661] Benveniste and Taghert, 1999, J. Neurobiol. 38(4): 507--520 Cell type-specific regulatory sequences control expression of the Drosophila FMRF-NH2 neuropeptide gene. [FBrf0107606] Benveniste et al., 1998, Development 125(23): 4757--4765 Cell type-specific regulation of the Drosophila FMRF-NH2 neuropeptide gene by apterous, a LIM homeodomain transcription factor. [FBrf0106026] Kolhekar et al., 1997, J. Neurosci. 17(4): 1363--1376 Neuropeptide amidation in Drosophila: separate genes encode the two enzymes catalyzing amidation. [FBrf0092591] Schneider et al., 1993, Neuron 10(2): 279--291 Cell type-specific transcriptional regulation of the Drosophila FMRFamide neuropeptide gene. [FBrf0059164]
Supplementary material	Allan et al., 2003, Cell 113(1): Supplementary material: tables S1 - S5. [FBrf0161463]

Allele Ecol\lacZFmrf.WF3

Allele Ecol\lacZ^Fmrf.WF3