Allele Dmel\Irbp^+t13

General Information
Symbol	Dmel\Irbp^+t13	Species	D. melanogaster
Name		FlyBase ID	FBal0050167
Feature type	allele	Associated gene	Dmel\Irbp

Allele class
Mutagen	in vitro construct - genomic fragment
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class
Mutagen	in vitro construct - genomic fragment (Beall and Rio, 1996)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Construct: 13kb SalI fragment encompassing the Irbp gene. (Beall and Rio, 1996)
Carried in construct	P{gIRBP13} (Gloor et al., 2000, Beall and Rio, 1996, Johnson-Schlitz et al., 2007)
Cytology
Phenotypic Data
Phenotypic Class
	wild-type (Beall and Rio, 1996)
Phenotype Manifest In

Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement Reference Irbp^+t13 is a suppressor of chemical sensitive phenotype of Blm^D3/Blm^D2 (Beall and Rio, 1996) Irbp^+t13 is a suppressor of female sterile phenotype of Blm^D3/Blm^D2 (Beall and Rio, 1996)
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference Rescues the female sterility and MMS sensitivity of mus309 mutants. (Beall and Rio, 1996)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Rescues	Irbp^+t13 rescues Irbp^EX8 (Johnson-Schlitz et al., 2007)
Comments	Irbp[+t13] rescues the chemical mutagen and gamma irradiation hypersensitivity of Irbp[EX8] mutants. Irbp[+t13] rescues the excess macrochaeta phenotype of Irbp[EX8] mutants. (Johnson-Schlitz et al., 2007)
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Irbp^+t13 mus309^+t13
Name Synonym
Secondary FlyBase IDs

References ( 3 )
Research paper	Johnson-Schlitz et al., 2007, PLoS Genet. 3(4): e50 Multiple-pathway analysis of double-strand break repair mutations in Drosophila. [FBrf0202217] Gloor et al., 2000, Genetics 155(4): 1821--1830 Distinct P-element excision products in somatic and germline cells of Drosophila melanogaster. [FBrf0129827] Beall and Rio, 1996, Genes Dev. 10(8): 921--933 Drosophila IRBP/Ku p70 corresponds to the mutagen-sensitive mus309 gene and is involved in P-element excision in vivo. [FBrf0086898]

Allele Dmel\Irbp+t13

Allele Dmel\Irbp^+t13