Allele Dmel\nonA^RRM1-RNP2

General Information
Symbol	Dmel\nonA^RRM1-RNP2	Species	D. melanogaster
Name		FlyBase ID	FBal0050209
Feature type	allele	Associated gene	Dmel\nonA

Allele class
Mutagen	in vitro construct - site directed mutagenesis, in vitro construct - amino acid replacement
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class
Mutagen	in vitro construct - amino acid replacement (Stanewsky et al., 1996) in vitro construct - site directed mutagenesis (Stanewsky et al., 1996)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Construct: Included within an 11kb XhoI-EcoRI fragment (compare to nonA^+tXhR11). Amino acid 13 (a Y) in the RNP2 of RRM1 is replaced by an A. (Stanewsky et al., 1996)
Carried in construct	P{RRM1-RNP2} (Stanewsky et al., 1996)
Cytology
Phenotypic Data
Phenotypic Class
	behavior defective (Stanewsky et al., 1996)
Phenotype Manifest In

Detailed Description
	Statement Reference In an otherwise nonA^- background, viability is only 6-7% that of controls carrying P{132XhR11}. Survivors are generally disorientated and do not fly. Flies placed on an open table top stand in place and barely walk or move their legs. Males fall over and cannot get up. Fails to rescue the optomotor blindness associated with nonA mutants. Light-on/light-off transient-less phenotype caused by nonA^- is not rescued. Males sing in a mutant manner, with wildly polycyclic pulses. (Stanewsky et al., 1996)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	nonA^RRM1-RNP2
Name Synonym
Secondary FlyBase IDs

References ( 1 )
Research paper	Stanewsky et al., 1996, Genetics 143(1): 259--275 Bioassaying putative RNA-binding motifs in a protein encoded by a gene that influences courtship and visually mediated behavior in Drosophila: In vitro mutagenesis of nonA. [FBrf0087722]

Allele Dmel\nonARRM1-RNP2

Allele Dmel\nonA^RRM1-RNP2