Open Close
General Information
Symbol
Dmel\rlS-135
Species
D. melanogaster
Name
FlyBase ID
FBal0050337
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement
Reference

rlS-135 is an enhancer of visible phenotype of PTP-ERhs.sev

rlS-135 is an enhancer of lethal phenotype of Raf12

rlS-135 is an enhancer of visible phenotype of Dsor1XS520

NOT Enhancer of
Statement
Reference

rlS-135 is a non-enhancer of visible phenotype of Pp2B-14Dact.GMR

NOT Suppressor of
Statement
Reference

rlS-135 is a non-suppressor of visible phenotype of Pp2B-14Dact.GMR

rlS-135 is a non-suppressor of visible phenotype of CanBGMR.PS, Pp2B-14Dact.GMR

Phenotype Manifest In
Enhancer of
Statement
Reference

rlS-135 is an enhancer of eye phenotype of PTP-ERhs.sev

rlS-135 is an enhancer of ommatidium phenotype of PTP-ERhs.sev

rlS-135 is an enhancer of eye phenotype of Raf12

rlS-135 is an enhancer of eye phenotype of Dsor1XS520

NOT Enhancer of
Statement
Reference

rlS-135 is a non-enhancer of eye phenotype of Pp2B-14Dact.GMR

rlS-135 is a non-enhancer of eye phenotype of CanBGMR.PS, Pp2B-14Dact.GMR

Suppressor of
Statement
Reference

rl[+]/rlS-135 is a suppressor | partially of eye | ectopic phenotype of Scer\GAL4dpp.blk1, eyaS-A.UAS

rlS-135 is a suppressor of phenotype of Ras85DV12.sev

NOT Suppressor of
Statement
Reference

rlS-135 is a non-suppressor of eye phenotype of Pp2B-14Dact.GMR

rlS-135 is a non-suppressor of eye phenotype of CanBGMR.PS, Pp2B-14Dact.GMR

Other
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

The penetrance of ectopic eye induction in eyaScer\UAS.cHa; Scer\GAL4dpp.blk1 flies is reduced from 98% (n=298) to 50% (n=313) by heterozygosity for rlS-135 and to 58% (n=313) (data from a single, 'strong' P{UAS-eya.H} insertion). The penetrance of ectopic eye induction in eyaS-A.Scer\UAS; Scer\GAL4dpp.blk1 flies is reduced from 42% (n=306) to 13% (n=310) by heterozygosity for rlS-135 (data from a single, 'strong' P{UAS-eyaS-A} insertion). The penetrance of ectopic eye induction in eyaS-A.Scer\UAS; Scer\GAL4dpp.blk1 flies is reduced from 42% (n=306) to 20% (n=304) by heterozygosity for eyaG130 (data from a single, 'strong' P{UAS-eyaS-A} insertion). The proportion of eyaScer\UAS.cHa; Scer\GAL4dpp.PH flies with blistered wings (76%) is decreased by heterozygosity for rlS-135 to 10%, while the proprotion with only mild wing defects is increased from 24% to 90%. (All data from experiments with a single, 'strong' P{UAS-eya.H} insertion; n=approximately 300 in each case).

Double heterozygotes rlS-135/PTP-ERhs.sev give a stronger eye phenotype than PTP-ERhs.sev alone.

Suppresses the rough eye phenotype of Ras85DV12.sev. Enhances the phenotype of Ras85DN17.sev. Suppresses the phenotype of phl::tor13D.hs.sev. Suppresses the phenotype of Ras85D::Src64BV12.ΔCAAX.sev. Enhances the lethality of phl12. Enhances the phl12 eye phenotype. Enhances the Dsor1XS520 eye phenotype. Enhances the aopS2382 eye phenotype.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (7)