embryonic/first instar larval cuticle & embryonic head
embryonic head & embryonic/first instar larval cuticle
Loss of Rho1rev220 enhances the shgg119 phenotype. Most double mutants have holes in their ventral epidermis that are not present in most shgg119 single mutants. As both Rho1rev220 and shgg119 affect head involution, the enhancement of this phenotype may simply reflect additive effects. However, because loss of Rho1rev220 does not affect integrity of the ventral epidermis, enhancement of this aspect of the phenotype is likely to reflect a genetic interaction.
Rho1rev220 enhances the weak shgg119 phenotype, leading to more severe embryonic defects. The percentage of phenotypically-wild-type embryos is reduced from approximately 7.6% in shgg119 embryos to approximately 0.5% in shgg119 Rho1rev220 mutants. The majority of shgg119 Rho1rev220 mutants (approximately 54%) exhibit ventral holes in the embryonic cuticle, compared to 21.7% in shgg119 mutants and 0.4% in Rho1rev220 mutants.