FB2025_01 , released February 20, 2025
Allele: Dmel\trhUAS.cWa
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General Information
Symbol
Dmel\trhUAS.cWa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Wilk
FlyBase ID
FBal0050669
Feature type
allele
Associated gene
Dmel\trh
Associated Insertion(s)
Carried in Construct
P{UAS-trh.W}
Also Known As
UAS-trh, P[UAS-trh]
Key Links
Transgenic product class
cDNA
(Wilk et al., 1996)
wild_type
(Wilk et al., 1996)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Wilk et al., 1996)
wild_type
(Wilk et al., 1996)
Mutagen
in vitro construct
(Wilk et al., 1996)
Progenitor genotype
Carried in construct
P{UAS-trh.W}
Cytology
Description

4.2kb cDNA clone containing the entire coding region is expressed from the UASt regulatory sequences.

(Wilk et al., 1996)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
trh
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of wild-type trhScer\UAS.cWa in the eye, under the regulation of Scer\GAL4GMR.PF or Scer\GAL4elav-C155 does not have an affect on eye ommatidial arrangement.

      (Sonnenfeld et al., 2005)

      When trhScer\UAS.cWa is expressed in the embryonic terminal regions by Scer\GAL4salm-459.2, extra tracheal pits are observed.

      (Boube et al., 2000)

      Early ubiquitous expression (driven by Scer\GAL4hs.2sev) results in the formation of extra tracheal pits, which go on to invaginate and migrate to form anterior and posterior lateral trunk branches. When driven by Scer\GAL469B or Scer\GAL4ptc-559.1 holes form in the epidermis.

      (Wilk et al., 1996)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of wild-type tgoScer\UAS.cWa and trhScer\UAS.cWa in the developing eye imaginal disc under the control of Scer\GAL4GMR.PF or Scer\GAL4elav-C155 results in a rough eye phenotype consisting of disruptions in the organisation of ommatidia and in mechanosensory bristles. Co-expression of tgoΔc.Scer\UAS and trhScer\UAS.cWa under the control of either Scer\GAL4GMR.PF or Scer\GAL4elav-C155 does not result in a rough eye phenotype.

      (Sonnenfeld et al., 2005)

      Co-expression of trhScer\UAS.cWa and vvlScer\UAS.cBa under the control of Scer\GAL4salm-459.2 induces ectopic tracheal fate.

      (Boube et al., 2000)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      trhScer\UAS.cWa
      trhUAS.cWa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Wilk
      (Wilk et al., 1996)
      Secondary FlyBase IDs
        References (10)