Allele Dmel\sev^unspecified

General Information
Symbol	Dmel\sev^unspecified	Species	D. melanogaster
Name		FlyBase ID	FBal0051170
Feature type	allele	Associated gene	Dmel\sev
Also Known As	unspecified

Allele class
Mutagen
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class
Mutagen
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In
	photoreceptor cell R7 (Zuker et al., 1987, Wernet et al., 2003) photoreceptor cell R7 of pale ommatidium (Wernet et al., 2006) photoreceptor cell R8 of yellow ommatidium \| ectopic (Wernet et al., 2006)
Detailed Description
	Statement Reference Marker analysis indicates that pale ommatidium type R8 cells adopt a yellow ommatidium R8 cell fate in sev[unspecified] homozygous eyes. (Wernet et al., 2006) The R8 cell of ommatidia of the dorsal rim area (DRA) of the eye develops normally in mutant animals. These flies lack all R7 cells. (Wernet et al., 2003) The eyelet has well developed rhabdomeres in mutant flies. (Yasuyama and Meinertzhagen, 1999) Displays locomotor activity rhythm with an approximately 24h period. (Vosshall and Young, 1995) Gap1^mip-w+ sev^unspecified flies have an excess of small rhabdomeres. (Buckles et al., 1992) Homozygotes lack the R7 photoreceptor cell. (Zuker et al., 1987) Pattern discrimination in sev^unspecified flies is similar to wild-type. The number of visits to pattern targets is less in sev^unspecified flies than wild-type. The reaction to the mid-point between two arranged targets is more in sev^unspecified flies than wild-type. sev^unspecified ort¹ double mutant flies show no pattern discrimination, but do show phototaxis to illuminated non-pattern targets. (Mimura, 1982)
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressed by
Statement Reference sev^unspecified has phenotype, suppressible by rl^Su14 (Lim et al., 1999) sev^unspecified has phenotype, suppressible by rl^Su23 (Lim et al., 1999)
NOT suppressed by
Statement Reference sev^unspecified has photoreceptor cell R7 of pale ommatidium phenotype, non-suppressible by ss^D115.7 (Wernet et al., 2006) sev^unspecified has photoreceptor cell R8 of yellow ommatidium \| ectopic phenotype, non-suppressible by ss^D115.7 (Wernet et al., 2006)
Additional Comments
Genetic Interactions
Statement Reference Transformation of pale ommatidium type R8 cells into yellow ommatidium type R8 cells in sev[unspecified] homozygous is unaffected if the eyes are also ss[D115.7]/ss[D115.7]. (Wernet et al., 2006)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Rescued by	sev^unspecified is rescued by sev^Δ22 (Bohmann et al., 1994)
Not rescued by	sev^unspecified is not rescued by sev^mHYBRID1 (Bowtell et al., 1988)
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	sev^unspecified unspecified (Papatsenko et al., 1997, Vosshall and Young, 1995, Mimura, 1982, Zuker et al., 1987)
Name Synonym
Secondary FlyBase IDs

References ( 12 )
Research paper	Wernet et al., 2006, Nature 440(7081): 174--180 Stochastic spineless expression creates the retinal mosaic for colour vision. [FBrf0191258] Wernet et al., 2003, Cell 115(3): 267--279 Homothorax switches function of Drosophila photoreceptors from color to polarized light sensors. [FBrf0167367] Maurel-Zaffran et al., 2001, Neuron 32(2): 225--235 Cell-autonomous and -nonautonomous functions of LAR in R7 photoreceptor axon targeting. [FBrf0139775] Lim et al., 1999, Genetics 153(2): 763--771 Genetic analysis of rolled, which encodes a Drosophila mitogen-activated protein kinase. [FBrf0111415] Yasuyama and Meinertzhagen, 1999, J. Comp. Neurol. 412(2): 193--202 Extraretinal photoreceptors at the compound eye's posterior margin in Drosophila melanogaster. [FBrf0111143] Papatsenko et al., 1997, Development 124(9): 1665--1673 A new rhodopsin in R8 photoreceptors of Drosophila: evidence for coordinate expression with Rh3 in R7 cells. [FBrf0093641] Vosshall and Young, 1995, Neuron 15(2): 345--360 Circadian rhythms in Drosophila can be driven by period expression in a restricted group of central brain cells. [FBrf0083505] Bohmann et al., 1994, Cell 78(6): 973--986 Drosophila Jun mediates Ras-dependent photoreceptor determination. [FBrf0076034] Buckles et al., 1992, Neuron 8: 1015--1029 mip causes hyperinnervation of a retinotopic map in Drosophila by excessive recruitment of R7 photoreceptor cells. [FBrf0057355] Bowtell et al., 1988, Genes Dev. 2: 620--634 Nucleotide sequence and structure of the sevenless gene of Drosophila melanogaster. [FBrf0048118] Zuker et al., 1987, J. Neurosci. 7: 1550--1557 A rhodopsin gene expressed in photoreceptor cell R7 of the Drosophila eye: homologies with other signal-transducing molecules. [FBrf0046830] Mimura, 1982, J. Comp. Physiol. A. 146(2): 229--233 Discrimination of some visual patterns in Drosophila melanogaster. [FBrf0063700]

Allele Dmel\sevunspecified

Allele Dmel\sev^unspecified