The rough eye phenotype seen in cswCS.hs.2sev flies is enhanced by the addition of dos1.46. The addition of doshs.2sev.cHa or dosYY.hs.2sev to cswCS.hs.2sev/dos1.46 flies strongly suppresses this phenotype. The addition of dosY854F.hs.2sev, dosY801F.hs.2sev.cHa, or dosY810F.Y854F.hs.2sev leads to markedly enhanced eye roughness.
Expression of Zzzz\cagAScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4hs.PB suppresses the lethality seen in dos1.46/dos2.42 mutants. 89% of the expected number of pupae are seen, compared to only 33% in homozygous dos1.46 mutants.
Expression of Zzzz\cagAScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4GMR.PF increases dos1.46 mutant clone size in the eye. The clones are much larger and contain increased numbers of photoreceptors.