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General Information
Symbol
Dmel\ciUAS.cAa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Alexandre
FlyBase ID
FBal0051700
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-ci
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of a full length ci cDNA.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Overexpression of ciScer\UAS.cAa under the control of Scer\GAL4pb.PJ leads to loss and disorganization of the pseudotracheal rows in the anterior compartment of the labial palps. This effect is less severe when flies are maintained at 22oC than when maintained at 28oC.

ciScer\UAS.cAa (when driven by Scer\GAL469B) induces a reduction in the number of denticles in a variable fashion. Enlargements of thoracic segments are seen which are covered in naked cuticle. This effect is penetrant when tested at 18oC 22oC and 29oC. At 29oC variable suppression of the first abdominal belt is seen, and sometimes all denticle belts of the abdomen.

Expression of ciScer\UAS.cAa under the control of Scer\GAL4bs-1348 results in a mild wing vein phenotype.

ciScer\UAS.cAa driven by Scer\GAL4cad-em459 produces very large anal plates, about twice the wild-type size. Anal plate bristles are also seen on the hindgut.

Animals expressing ciScer\UAS.cAa under the control of Scer\GAL4αTub84B.PP in an hhts2 background that have been raised at 28oC after hatching contain S phase lamina neuron precursors (LPCs) in the lamina.

Scer\GAL430A induced expression causes lethality during late larval or pupal stages, pharate adults exhibit outgrowths from the proximal wing region.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
NOT suppressed by
Statement
Reference
Phenotype Manifest In
Enhanced by
Suppressed by
NOT suppressed by
Statement
Reference
Other
Additional Comments
Genetic Interactions
Statement
Reference

Expression of ciScer\UAS.cAa under the control of Scer\GAL4pb.PJ in pb5/+ heterozygotes enhances the reduced pseudotracheal row phenotype of ciScer\UAS.cAa single mutants. When pbScer\UAS.A is overexpressed along with ciScer\UAS.cAa, both under the control of Scer\GAL4pb.PJ, the pseudotracheal row phenotype is suppressed and labial palps appear almost the same as wild type.

When ciScer\UAS.cAa (driven by Scer\GAL469B) is expressed in a wgl-17 background the naked cell fate is induced in the thorax and the most anterior part of the abdomen. Unpigmented denticles are seen in the posterior trunk. However, when ciScer\UAS.cAa is driven by Scer\GAL4αTub84B.PP in a wgl-17 background, naked cuticle is formed in the thorax but denticles are present throughout the abdomen. If ciScer\UAS.cAa is driven by Scer\GAL4wg.PM in a wgl-17 background naked cuticle is produced in a cell autonomous manner. The addition of ciScer\UAS.cAa (driven by Scer\GAL4αTub84B.PP) to arm2 germ-line clones, can suppress denticle belt formation in the thorax of mutant embryos but not in the abdomen. The addition of ciScer\UAS.cAa (driven by Scer\GAL4αTub84B.PP) to tsh8 mutant embryos, can suppress denticle belt formation in the thorax and the abdomen.

Su(hh)IIII or Su(hh)IIIIII rescue the wing vein patterning of animals expressing ciScer\UAS.cAa under the control of Scer\GAL4bs-1348 to almost wild type. Su(hh)IVIV rescues to almost wild type the wing vein patterning in the anterior compartment of the wing of animals expressing ciScer\UAS.cAa under the control of Scer\GAL4bs-1348.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
ciScer\UAS.cAa
ciUAS.cAa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Alexandre
Secondary FlyBase IDs
    References (10)