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General Information
Symbol
Dmel\bowl2
Species
D. melanogaster
Name
FlyBase ID
FBal0051736
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
point mutation
Nucleotide change:

C3780575T

Reported nucleotide change:

C1194T

Amino acid change:

H284Y | bowl-PA; H284Y | bowl-PB; H284Y | bowl-PC; H284Y | bowl-PD; H284Y | bowl-PF; H284Y | bowl-PG; H284Y | bowl-PH

Reported amino acid change:

H284Y

Comment:

His20 of 2nd zinc finger

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Amino acid replacement: H284Y.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

When homozygous clones are made that occupy most of the distal leg, mutant animals exhibit severe fusion and truncation of the tarsus. Clones that only span inter-tarsomere joints appear normal. Almost all clones that result in observable phenotypes span the tibia/t1 boundary and within these clones there is considerable variation in the number of tarsomere joints affected.

Homozygous embryos exhibit the 'tail-up' phenotype and defects in the mandible and maxilla. Hindgut is drastically reduced, proventriculus is absent. Lateralgraten is shortened and the ventral arm reduced in bowl1/bowl2 transheterozygotes.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
Comments
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (6)