A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

Allele Scer\GAL4Mef2.PR

General Information
SymbolScer\GAL4Mef2.PRSpeciesS. cerevisiae
NameMyocyte enhancing factor 2 promoter construct of RanganayakuluFlyBase IDFBal0052385
Feature typealleleAssociated geneScer\GAL4
Allele class
Mutagenin vitro construct - regulatory fusion
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Description
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FB2013_03
FB2013_02
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Allele class
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Associated Sequence Data
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DNA sequence
Protein sequence
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Progenitor genotype
Nature of the lesion
Statement
Reference
9.4kb genomic fragment containing Mef2 enhancer and promoter sequences necessary for somatic, visceral and cardiac muscle lineage expression controls the expression of Scer\GAL4.
Construct: Somatic, visceral and cardiac regulatory elements of Mef2 are fused upstream of Scer\GAL4.
Carried in construct
(Banerjee et al., 2004, Haghighi et al., 2003, Artero et al., 2001, McCabe et al., 2003, Sanyal et al., 2005, Carmena et al., 2002, Roper et al., 2005, Keegan et al., 2005, Dolezal et al., 2005, Muratoglu et al., 2006, Beckett and Baylies, 2006, Wayburn and Volk, 2009, Torgler et al., 2004, Deng et al., 2009, Caygill and Johnston, 2008, Artero et al., 2003, Sullivan et al., 2000, Cox and Baylies, 2005, Mandal et al., 2004, Galletta et al., 2004, Schumacher et al., 2004, Grabbe et al., 2004, Golby et al., 2001, Carmena et al., 1998, Ranganayakulu et al., 1996, Ranganayakulu et al., 1998, Michelson et al., 1998, Greene et al., 2003, Yi et al., 2006, Yi, 2006, Santiago-Martinez et al., 2006, Bai et al., 2007, Qian and Bodmer, 2009, Parker et al., 2006, Volohonsky et al., 2007, Subramanian et al., 2007, Dietzl et al., 2007, Schnorrer et al., 2007, Beuchle et al., 2007, Loer et al., 2008, Loer et al., 2008, Pak et al., 2011, Guan et al., 2011, Carrasco-Rando et al., 2011, Stavropoulos and Young, 2011, Balagopalan et al., 2006, Geisbrecht et al., 2008, Rotkopf et al., 2011, Biersmith et al., 2011, Nowak et al., 2012, Lahaye et al., 2012, Vanderploeg et al., 2012, Nir et al., 2012, Schönbauer et al., 2011, Rideout et al., 2012, Markstein et al., 2008, Cauchi et al., 2008, Lindsay et al., 2008, Tzortzopoulos and Skoulakis, 2007, Pentek et al., 2009, Siebert et al., 2009, Vicente et al., 2007, Hudson et al., 2008, Kocherlakota et al., 2008, Park et al., 2009, Martin et al., 2009, Massarwa et al., 2009, Carrasco-Rando and Ruiz-Gómez, 2008, Gilsohn and Volk, 2010, Zimmermann et al., 2006, Chen et al., 2008, Wagner et al., 2010, Scantlebury et al., 2010, Schulze et al., 2009, Langer et al., 2010, Lee et al., 2007, Bland et al., 2010, Banovic et al., 2010, Lee et al., 2010, Blanchard et al., 2010, Schnorrer et al., 2010, Schnorrer, 2009.3.22, Park et al., 2010, Qian et al., 2008, Tanentzapf et al., 2006, Tennessen et al., 2011, Freeman et al., 2011, Zervas et al., 2011, Franco-Cea et al., 2010, Deng et al., 2008, Grigorian et al., 2011, Demontis and Perrimon, 2010, Shirinian et al., 2010, Weake et al., 2011, Kim et al., 2011, Park et al., 2011, van Impel et al., 2009, Rossetto et al., 2011, Katzemich et al., 2011, Vrailas-Mortimer et al., 2011, Deng et al., 2010, Dottermusch-Heidel et al., 2012, Bricker et al., 2012, Elhanany-Tamir et al., 2012, Vakaloglou et al., 2012, Katzemich et al., 2012, Susic-Jung et al., 2012, Bulchand et al., 2010, Guerin and Kramer, 2009, Park et al., 2006, Okamoto et al., 2013, Chinta et al., 2012, Bharadwaj et al., 2013, Kumar et al., 2009, Chen et al., 2012, Shelton et al., 2009)
Cytology
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embryonic/larval heart & mesoderm, with Mmus\Nkx2-5Scer\UAS.cRa, Scer\GAL4twi.PB
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Reference
Mmus\Nkx2-5Scer\UAS.cRa, Scer\GAL4Mef2.PR, Scer\GAL4twi.PB has embryonic/larval heart & mesoderm phenotype, suppressible | partially by tinEC40
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Reference
Scer\GAL4twi.PB, Mmus\Nkx2-5Scer\UAS.ΔNK, Scer\GAL4Mef2.PR is a suppressor | partially of embryonic/larval heart & mesoderm phenotype of tinEC40
Scer\GAL4twi.PB, Scer\GAL4Mef2.PR, Mmus\Nkx2-5Scer\UAS.cRa is a suppressor | partially of embryonic/larval heart & mesoderm phenotype of tinEC40
Scer\GAL4twi.PB, Scer\GAL4Mef2.PR, tin::Mmus\Nkx2-5Scer\UAS.HDs is a suppressor of embryonic/larval heart & mesoderm phenotype of tinEC40
Scer\GAL4twi.PB, Scer\GAL4Mef2.PR, tin::Mmus\Nkx2-5Scer\UAS.tin.1-220 is a suppressor of embryonic/larval heart & mesoderm phenotype of tinEC40
Scer\GAL4twi.PB, Scer\GAL4Mef2.PR, tin::Mmus\Nkx2-5Scer\UAS.tin-HD,Nkx is a suppressor of embryonic/larval heart & mesoderm phenotype of tinEC40
Scer\GAL4twi.PB, tin::Mmus\Nkx2-5Scer\UAS.tin-Nkx, Scer\GAL4Mef2.PR is a suppressor of embryonic/larval heart & mesoderm phenotype of tinEC40
tin::Mmus\Nkx2-5Scer\UAS.1-53:54-319, Scer\GAL4twi.PB, Scer\GAL4Mef2.PR is a suppressor | partially of embryonic/larval heart & mesoderm phenotype of tinEC40
tin::Mmus\Nkx2-5Scer\UAS.tin.1-134, Scer\GAL4twi.PB, Scer\GAL4Mef2.PR is a suppressor of embryonic/larval heart & mesoderm phenotype of tinEC40
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Reported As
Symbol Synonym
GAL4Mef2.PR
 
Scer\GAL4Mef2.PR
 
Name Synonym
Myocyte enhancing factor 2 promoter construct of Ranganayakulu
Secondary FlyBase IDs
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hide Recent research papers ( 35 )
Bharadwaj et al., 2013, Development 140(3): 627--638
Cbl-associated protein regulates assembly and function of two tension-sensing structures in Drosophila. [FBrf0220383]
Okamoto et al., 2013, Genes Dev. 27(1): 87--97
A secreted decoy of InR antagonizes insulin/IGF signaling to restrict body growth in Drosophila. [FBrf0220509]
Uchino et al., 2013, Dev. Biol. 373(1): 216--227
Loss of Drosophila A-type lamin C initially causes tendon abnormality including disintegration of cytoskeleton and nuclear lamina in muscular defects. [FBrf0220052]
Bricker et al., 2012, Science 337(6090): 96--100
A mitochondrial pyruvate carrier required for pyruvate uptake in yeast, Drosophila, and humans. [FBrf0218824]
Chen et al., 2012, Development 139(19): 3543--3552
miR-92b regulates Mef2 levels through a negative-feedback circuit during Drosophila muscle development. [FBrf0219365]
Chinta et al., 2012, BMC Bioinformatics 13 Suppl 17: S14
The study of muscle remodeling in Drosophila metamorphosis using in vivo microscopy and bioimage informatics. [FBrf0220485]
Dialynas et al., 2012, Hum. Mol. Genet. 21(7): 1544--1556
LMNA variants cause cytoplasmic distribution of nuclear pore proteins in Drosophila and human muscle. [FBrf0217713]
Dottermusch-Heidel et al., 2012, Dev. Biol. 368(1): 18--27
The Arf-GEF Schizo/Loner regulates N-cadherin to induce fusion competence of Drosophila myoblasts. [FBrf0218661]
Elhanany-Tamir et al., 2012, J. Cell Biol. 198(5): 833--846
Organelle positioning in muscles requires cooperation between two KASH proteins and microtubules. [FBrf0219334]
Katzemich et al., 2012, J. Cell Sci. 125(14): 3367--3379
The function of the M-line protein obscurin in controlling the symmetry of the sarcomere in the flight muscle of Drosophila. [FBrf0219368]
Lahaye et al., 2012, PLoS ONE 7(3): e32297
WNT5 Interacts with the Ryk Receptors Doughnut and Derailed to Mediate Muscle Attachment Site Selection in Drosophila melanogaster. [FBrf0217725]
Nir et al., 2012, PLoS Genet. 8(3): e1002632
Phosphorylation of the Drosophila melanogaster RNA-Binding Protein HOW by MAPK/ERK Enhances Its Dimerization and Activity. [FBrf0217996]
Nowak et al., 2012, PLoS Genet. 8(3): e1002547
Akirin Links Twist-Regulated Transcription with the Brahma Chromatin Remodeling Complex during Embryogenesis. [FBrf0217616]
Rideout et al., 2012, Proc. Natl. Acad. Sci. U.S.A. 109(4): 1139--1144
Drosophila RNA polymerase III repressor Maf1 controls body size and developmental timing by modulating tRNAiMet synthesis and systemic insulin signaling. [FBrf0217359]
Sujkowski et al., 2012, Aging Cell 11(6): 921--932
dFatp regulates nutrient distribution and long-term physiology in Drosophila. [FBrf0220246]
Susic-Jung et al., 2012, Dev. Biol. 370(1): 86--97
Multinucleated smooth muscles and mononucleated as well as multinucleated striated muscles develop during establishment of the male reproductive organs of Drosophila melanogaster. [FBrf0219326]
Vakaloglou et al., 2012, J. Cell Sci. 125(13): 3221--3232
Functional analysis of parvin and different modes of IPP-complex assembly at integrin sites during Drosophila development. [FBrf0219290]
Vanderploeg et al., 2012, BMC Dev. Biol. 12: 8
Integrins are required for cardioblast polarisation in Drosophila. [FBrf0217831]
Biersmith et al., 2011, PLoS ONE 6(1): e16120
The DOCK Protein Sponge Binds to ELMO and Functions in Drosophila Embryonic CNS Development. [FBrf0212890]
Carrasco-Rando et al., 2011, PLoS Genet. 7(7): e1002186
Drosophila araucan and caupolican integrate intrinsic and signalling inputs for the acquisition by muscle progenitors of the lateral transverse fate. [FBrf0214635]
Freeman et al., 2011, Mol. Cell. Neurosci. 46(2): 535--547
NFAT regulates pre-synaptic development and activity-dependent plasticity in Drosophila. [FBrf0212894]
Grigorian et al., 2011, Dev. Biol. 353(1): 105--118
The convergence of Notch and MAPK signaling specifies the blood progenitor fate in the Drosophila mesoderm. [FBrf0213410]
Guan et al., 2011, Learn. Mem. 18(4): 191--206
Altered gene regulation and synaptic morphology in Drosophila learning and memory mutants. [FBrf0213277]
Katzemich et al., 2011, Gene Expr. Patterns 11(8): 484--490
Muscle type-specific expression of Zasp52 isoforms in Drosophila. [FBrf0216438]
Kim et al., 2011, BMC Physiol. 11: 7
Expression of human amyloid precursor protein in the skeletal muscles of Drosophila results in age- and activity-dependent muscle weakness. [FBrf0213903]
Pak et al., 2011, Proc. Natl. Acad. Sci. U.S.A. 108(30): 12390--12395
Mutation of the conserved polyadenosine RNA binding protein, ZC3H14/dNab2, impairs neural function in Drosophila and humans. [FBrf0214553]
Park et al., 2011, PLoS Genet. 7(8): e1002241
Specification of Drosophila corpora cardiaca neuroendocrine cells from mesoderm is regulated by Notch signaling. [FBrf0215231]
Rossetto et al., 2011, Hum. Mol. Genet. 20(21): 4248--4257
Defhc1.1, a homologue of the juvenile myoclonic gene EFHC1, modulates architecture and basal activity of the neuromuscular junction in Drosophila. [FBrf0216330]
Rotkopf et al., 2011, Development 138(13): 2729--2739
The WASp-based actin polymerization machinery is required in somatic support cells for spermatid maturation and release. [FBrf0213892]
Schönbauer et al., 2011, Nature 479(7373): 406--409
Spalt mediates an evolutionarily conserved switch to fibrillar muscle fate in insects. [FBrf0216735]
Stavropoulos and Young, 2011, Neuron 72(6): 964--976
insomniac and Cullin-3 Regulate Sleep and Wakefulness in Drosophila. [FBrf0217043]
Tennessen et al., 2011, Cell Metab. 13(2): 139--148
The Drosophila Estrogen-Related Receptor Directs a Metabolic Switch that Supports Developmental Growth. [FBrf0212927]
Vrailas-Mortimer et al., 2011, Dev. Cell 21(4): 783--795
A Muscle-Specific p38 MAPK/Mef2/MnSOD Pathway Regulates Stress, Motor Function, and Life Span in Drosophila. [FBrf0216446]
Weake et al., 2011, Genes Dev. 25(14): 1499--1509
Post-transcription initiation function of the ubiquitous SAGA complex in tissue-specific gene activation. [FBrf0214372]
Zervas et al., 2011, J. Cell Sci. 124(8): 1316--1327
A central multifunctional role of integrin-linked kinase at muscle attachment sites. [FBrf0213331]