Allele Scer\GAL4^34B

General Information
Symbol	Scer\GAL4^34B	Species	S. cerevisiae
Name		FlyBase ID	FBal0052393
Feature type	allele	Associated gene	Scer\GAL4

Allele class
Mutagen	P-element activity
Recent Updates
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	P-element activity (Ingham and Fietz, 1995, Brand, 1997.6.30)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Caused by insertion	P{GawB}34B (Ingham and Fietz, 1995, Brand, 1997.6.30, Akten et al., 2002, Haines and van Den Heuvel, 2000, Andrews et al., 2002, Yin and Thummel, 2004, Ward et al., 2003, Choi et al., 2006, Gilbert et al., 2006, Shalaby et al., 2009, Costantino et al., 2008, Morris et al., 2006, Leulier et al., 2006, Georgiev et al., 2010)
Cytology
Phenotypic Data
Phenotypic Class
	increased cell death, with th^{dsRNA.Scer\UAS} (Choi et al., 2006) increased cell death, with th^Scer\UAS.cHa (Choi et al., 2006) lethal, with dy^{dsRNA.Scer\UAS} (Akten et al., 2002) lethal, with E2f^Scer\UAS.cNa (Morris et al., 2006) lethal, with Hsap\CDKN1A^Scer\UAS.cHa (Morris et al., 2006) lethal, with rpr^Scer\UAS.cZa (Morris et al., 2006) viable, with sec10^{dsRNA.Scer\UAS} (Andrews et al., 2002) visible, with Drer\shh^Scer\UAS.cIa (Haines and van Den Heuvel, 2000)
Phenotype Manifest In
	chemosensory ventral triple row bristle, with Drer\shh^Scer\UAS.cIa (Ingham and Fietz, 1995) dorsal triple row, with Drer\shh^Scer\UAS.cIa (Ingham and Fietz, 1995) mechanosensory ventral triple row bristle, with Drer\shh^Scer\UAS.cIa (Ingham and Fietz, 1995) medial triple row, with Drer\shh^Scer\UAS.cIa (Ingham and Fietz, 1995) mitochondrion, with trpm^GD4541 (Georgiev et al., 2010) polytene chromosome \| third instar larval stage, with BEAF-32^{BID.Scer\UAS.T:Ivir\HA1,T:SV40\nls2} (Gilbert et al., 2006) salivary gland \| pupal stage, with Ark^{dsRNA.Scer\UAS.cLa} (Leulier et al., 2006) salivary gland \| pupal stage, with BacA\p35^Scer\UAS.cHa (Leulier et al., 2006) salivary gland \| pupal stage, with dream^{dsRNA.Scer\UAS.cLa} (Leulier et al., 2006) salivary gland \| pupal stage, with Ice^{dsRNA.Scer\UAS.cLa} (Leulier et al., 2006) salivary gland \| pupal stage, with Nc^{dsRNA.Scer\UAS.cLa} (Leulier et al., 2006) ventral triple row, with Drer\shh^Scer\UAS.cIa (Ingham and Fietz, 1995) wing, with Drer\shh^Scer\UAS.cIa (Haines and van Den Heuvel, 2000) wing, with dy^{dsRNA.Scer\UAS} (Akten et al., 2002) wing \| anterior \| proximal, with hh^Scer\UAS.cIa (Ingham and Fietz, 1995) wing \| anterior compartment, with hh^Scer\UAS.cIa (Ingham and Fietz, 1995) wing vein, with Dl^D.Scer\UAS (Shalaby et al., 2009)
Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhanced by
Statement Reference Dl^D.Scer\UAS, Scer\GAL4^34B has wing vein phenotype, enhanceable by kst[+]/kst^d11183, Scer\GAL4^34B (Shalaby et al., 2009, Shalaby et al., 2009)
Suppressed by
Statement Reference Dl^D.Scer\UAS, Scer\GAL4^34B has wing vein phenotype, suppressible \| partially by Amun[+]/Amun^d03329, Scer\GAL4^34B (Shalaby et al., 2009, Shalaby et al., 2009)
Enhancer of
Statement Reference kst[+]/kst^d11183, Scer\GAL4^34B is an enhancer of wing vein phenotype of Dl^D.Scer\UAS, Scer\GAL4^34B (Shalaby et al., 2009, Shalaby et al., 2009)
Suppressor of
Statement Reference Amun[+]/Amun^d03329, Scer\GAL4^34B is a suppressor \| partially of wing vein phenotype of Dl^D.Scer\UAS, Scer\GAL4^34B (Shalaby et al., 2009, Shalaby et al., 2009)
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Rescues	Scer\GAL4^34B/th^Scer\UAS.cHa rescues th^{dsRNA.Scer\UAS} (Choi et al., 2006)
Comments
Stocks ( 1 )
Bloomington	1967 y¹ w^*; P{GawB}34B
Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	GAL4^34B Scer\GAL4^34B
Name Synonym
Secondary FlyBase IDs

References ( 14 )
Research paper	Georgiev et al., 2010, Cell Metab. 12(4): 386--397 TRPM Channels Mediate Zinc Homeostasis and Cellular Growth during Drosophila Larval Development. [FBrf0211938] Shalaby et al., 2009, Genetics 182(4): 1061--1076 A screen for modifiers of notch signaling uncovers amun, a protein with a critical role in sensory organ development. [FBrf0208696] Costantino et al., 2008, PLoS Genet. 4(6): e1000102 A novel ecdysone receptor mediates steroid-regulated developmental events during the mid-third instar of Drosophila. [FBrf0205257] Choi et al., 2006, Development 133(11): 2223--2232 Programmed cell death mechanisms of identifiable peptidergic neurons in Drosophila melanogaster. [FBrf0190281] Gilbert et al., 2006, Genetics 173(3): 1365--1375 The Drosophila boundary element-associated factors BEAF-32A and BEAF-32B affect chromatin structure. [FBrf0192350] Leulier et al., 2006, Cell Death Differ. 13(10): 1663--1674 Systematic in vivo RNAi analysis of putative components of the Drosophila cell death machinery. [FBrf0192581] Morris et al., 2006, PLoS Genet. 2(11): e147 Functional identification of Api5 as a suppressor of E2F-dependent apoptosis in vivo. [FBrf0194141] Yin and Thummel, 2004, Proc. Natl. Acad. Sci. U.S.A. 101(21): 8022--8027 A balance between the diap1 death inhibitor and reaper and hid death inducers controls steroid-triggered cell death in Drosophila. [FBrf0179526] Ward et al., 2003, Dev. Biol. 256(2): 389--402 GFP in living animals reveals dynamic developmental responses to ecdysone during Drosophila metamorphosis. [FBrf0158851] Akten et al., 2002, genesis 34(1-2): 156--159 RNA interference from a CAX trinucleotide repeat. [FBrf0152369] Andrews et al., 2002, Traffic 3(12): 906--921 Drosophila Sec10 is required for hormone secretion but not general exocytosis or neurotransmission. [FBrf0156063] Haines and van Den Heuvel, 2000, Genetics 156(4): 1777--1785 A directed mutagenesis screen in Drosophila melanogaster reveals new mutants that influence hedgehog signaling. [FBrf0131307] Ingham and Fietz, 1995, Curr. Biol. 5(4): 432--440 Quantitative effects of hedgehog and decapentaplegic activity on the patterning of the Drosophila wing. [FBrf0082166]
Personal communication to FlyBase	Brand, 1997.6.30, P{GawB} insertions. P{GawB} insertions. [FBrf0098595]

Allele Scer\GAL434B

Allele Scer\GAL4^34B