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General Information
Symbol
Dmel\tkvunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0055978
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
unspecified
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Stage 15 tkvunspecified embryos have 30-34 genital disc precursor cells, while wild type embryos have only 22 at this stage.

    The number of T bars per active zone and bouton surface area per active zone is increased compared to wild type in the boutons of muscle 6/7 in mutant third instar larvae. 10 +/- 2% detachment of the presynaptic membrane is seen.

    Homozygotes do not exhibit a wing vein phenotype.

    tkvunspecified mutant embryos lack dorsal hypoderm. Internal organs appear normal and are extruded though the open dorsal side of the embryo. The ventral hypoderm is contracted.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    Suppressed by
    Statement
    Reference
    Suppressor of
    Statement
    Reference
    NOT Suppressor of
    Statement
    Reference

    tkvunspecified/tkv[+] is a non-suppressor of wing vein | ectopic phenotype of EgfrE1

    Other
    Additional Comments
    Genetic Interactions
    Statement
    Reference

    Introduction of sogEP2 into tkvunspecified flies causes truncation of wing vein L4 and introduction of sogEP7 causes severe truncation of wing veins L4 and L5.

    Egfrt1/Egfrf11 shows a negative interaction in combination with tkvunspecified/tkvunspecified.

    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    Name Synonyms
    Secondary FlyBase IDs
      References (12)