Allele Dmel\su(Hw)^ΔCTAD

General Information
Symbol	Dmel\su(Hw)^ΔCTAD	Species	D. melanogaster
Name		FlyBase ID	FBal0056044
Feature type	allele	Associated gene	Dmel\su(Hw)

Allele class
Mutagen	in vitro construct - deletion
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class
Mutagen	in vitro construct - deletion (Gdula and Corces, 1997)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype	su(Hw)^+t5.2 (Gdula and Corces, 1997)
Nature of the lesion	Statement Reference Construct: Amino acid replacement: G861@. Nucleotide substitution: G3512T, (numbering according to FBrf0048095). The stop codon at position 861 effectively produces a deletion of the carboxy-terminal acidic domain. (Gdula and Corces, 1997)
Carried in construct	P{su(Hw)^ΔCTAD} (Gdula and Corces, 1997)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In

Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressor of
Statement Reference su(Hw)^ΔCTAD/mod(mdg4)^ul is a suppressor of phenotype of y² (Gdula and Corces, 1997)
Other
Statement Reference mod(mdg4)^ul, su(Hw)^ΔCTAD, y² has abdomen phenotype (Gdula and Corces, 1997, Gdula and Corces, 1997, Gdula and Corces, 1997) mod(mdg4)^ul, su(Hw)^ΔCTAD, y² has cuticle phenotype (Gdula and Corces, 1997) mod(mdg4)^ul, su(Hw)^ΔCTAD, y² has macrochaeta phenotype (Gdula and Corces, 1997, Gdula and Corces, 1997, Gdula and Corces, 1997) mod(mdg4)^ul, su(Hw)^ΔCTAD, y² has unguis phenotype (Gdula and Corces, 1997, Gdula and Corces, 1997, Gdula and Corces, 1997) mod(mdg4)^ul, su(Hw)^ΔCTAD, y² has wing phenotype (Gdula and Corces, 1997, Gdula and Corces, 1997, Gdula and Corces, 1997)
Additional Comments
Genetic Interactions
Statement Reference Shows complete repression of the y body and wing enhancers. When crossed into a y², mod(mdg4)^ul mutant background the flies display bristle, tarsal claws, abdomen and wings with a coloration between null mutant and wild type. (Gdula and Corces, 1997)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

Comments
	Mutant protein completely represses y distal enhancer function. (Gdula and Corces, 1997)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	su(Hw)^ΔCTAD
Name Synonym
Secondary FlyBase IDs

References ( 2 )
Research paper	Ghosh et al., 2001, EMBO J. 20(10): 2518--2527 Interactions between the Su(Hw) and Mod(mdg4) proteins required for gypsy insulator function. [FBrf0136690] Gdula and Corces, 1997, Genetics 145(1): 153--161 Characterization of functional domains of the su(Hw) protein that mediate the silencing effect of mod(mdg4) mutations. [FBrf0091383]

Allele Dmel\su(Hw)ΔCTAD

Allele Dmel\su(Hw)^ΔCTAD