FB2025_01 , released February 20, 2025
Allele: Dmel\zf30Ck02506
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General Information
Symbol
Dmel\zf30Ck02506
Species
D. melanogaster
Name
FlyBase ID
FBal0057096
Feature type
allele
Associated gene
Dmel\zf30C
Associated Insertion(s)
P{lacW}zf30Ck02506
Carried in Construct
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Cook, 2002.3.7)
Mutagen
P-element activity
(Beaton, 1997.3.4)
Progenitor genotype
Associated Insertion(s)
P{lacW}zf30Ck02506
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      zf30Ck02506 in combination with Df(2L)30A-C, Df(2L)γ7, Df(2L)N22-3 or Df(2L)s1402 gave incompletely penetrant shortening of the L5 wing vein and posterior crossvein. L5 vein shortening was seen in a minority of flies and PCV shortening was uncommon. Females (and males) carrying zf30Ck02506 in combination with Df(2L)30A-C, Df(2L)γ7, Df(2L)N22-3 or Df(2L)s1402 were all fertile.

      (Cook, 2002.3.7)

      Stated to be lethal. See Cook, 2002.3.7, personal communication to FlyBase for revision of phenotypic data.

      (Spradling et al., 1999, Beaton, 1997.3.4)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Complements

      zf30CEP518

      (Cook, 2002.3.7)
      Partially complements

      zf30CEP2228

      (Cook, 2002.3.7)
      Fails to complement

      zf30Ck02510

      (BDGP Project Members, 1994-1999)
      Comments

      The phenotypes of zf30CEP518 and zf30CEP2228 in combination with zf30Ck02506 were less severe than phenotypes in combination with the deletions. No wing defects or female sterility was seen in zf30CEP518/zf30Ck02506 flies. zf30CEP2228/zf30Ck02506 flies showed only weakly penetrant L5 shortening or thinning, and females were fertile. Dp(2;Y)cb50; zf30Ck02506/Df(2L)s1402 males were normal.

      (Cook, 2002.3.7)
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer

      Separable from: l(2)DB2k025.

      (Cook, 2002.3.7)
      Comments
      Comments

      The severity of the zf30C alleles can be ranked zf30Ck02506 < zf30CEP518 < zf30CEP2228 in terms of wing phenotype and female sterility. Complements: undΔ34.

      (Cook, 2002.3.7)

      Complements: hoipk05712. Complements: FKBP59k09010.

      (BDGP Project Members, 1994-1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      l(2)k02506
      (Spradling et al., 1999)
      l(2)k02506k02506
      (Beaton, 1997.3.4, BDGP Project Members, 1994-1999)
      zf30Ck02506
      zf30ck02506
      (Jafari et al., 2012)
      Name Synonyms
      Secondary FlyBase IDs
        References (6)