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General Information
Symbol
Dmel\kuzUAS.cFa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Fambrough
FlyBase ID
FBal0057208
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-kuz, UAS-KUZ-F
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

A 4.9kb kuz cDNA fragment, containing the entire coding region, is expressed under the control of UASt regulatory sequences.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Wild-type flies expressing kuzScer\UAS.cFa under the control of Scer\GAL4Mef2.247.Switch exhibit wild-type memory performance, indicating that expression of kuzScer\UAS.cFa in the mushroom bodies has no impact on short-term memory.

Expression of kuzScer\UAS.cFa in egg chambers (under the control of Scer\GAL4slbo.2.6) has no detectable effect.

Expression of kuzScer\UAS.cFa under the control of Scer\GAL4slbo.2.6 does not result in defects in border follicle cell migration.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement
Reference
NOT Enhancer of
Statement
Reference
Suppressor of
NOT Suppressor of
Statement
Reference
Phenotype Manifest In
Suppressor of
NOT Suppressor of
Additional Comments
Genetic Interactions
Statement
Reference

Expression of kuzScer\UAS.cFa in a Appld/+; Scer\GAL4Mef2.247.Switch heterozygous background exacerbates the short term memory deficit found in this background. These flies exhibit this exacerbated defect regardless of whether the flies are fed with RU for 48 hours before conditioning. Appld/+; Scer\GAL4Mef2.247.Switch/kuzScer\UAS.cFa flies fed with RU and testing immediately after conditioning exhibit wild-type learning. The ability to avoid electric shocks as well as their olfactory acuity to each odour after electric shock exposure is unaffected.

Expression of kuzScer\UAS.cFa under the control of Scer\GAL4Appl.G1a suppresses the increase in vacuolisation seen in the brains of SNF4Aγloe mutant third instar larvae.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Partially rescues
Comments

Rescues the defect in axon tract formation of kuzunspecified flies when expression is driven by Scer\GAL4elav-C155.

Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
kuzScer\UAS.cFa
kuzUAS.cFa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Fambrough
Secondary FlyBase IDs
    References (11)