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General Information
Symbol
Dmel\klgE226
Species
D. melanogaster
Name
FlyBase ID
FBal0057231
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

The klg ORF is entirely deleted in the klgE226 mutation, although the 3' end of the deletion has not been determined.

Imprecise excision of the P{HZ} element, resulting in a deletion (extending in both directions from the site of the P{HZ} element insertion) that removes the entire klg open reading frame.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

1-day memory after spaced training is disrupted in klgGS10439/klgE226 and klgruslan/klgE226 flies.

Homozygotes die as second instar larvae. The overall structure of the embryonic central nervous system develops normally. Homozygous clones in the eye show no alteration in the number or morphology of the photoreceptors.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement
Reference

klgE226/klgGS10439 is a suppressor of memory defective | heat sensitive phenotype of NHsp70Bb.PL

Phenotype Manifest In
Other
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

The enhancement of long-term memory by NHsp70Bb.PL over-expression is suppressed in klgGS10439/klgE226 flies.

Reduces the proportion of ommatidia containing an R7 cell in sev6/Y ; SosJC2/+ flies.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Partially rescued by
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (5)