glial cell & eye disc | somatic clone | cell non-autonomous, with Scer\GAL4Act5C.PP
When hhScer\UAS.cAa and eyScer\UAS.cHa are expressed in clones (under the control of Scer\GAL4Act5C.PI) in the anterior compartment of the wing disc, 46% of clones cause ectopic eye formation. When hhScer\UAS.cAa and eyScer\UAS.cHa are expressed under the control of Scer\GAL430A in the anterior compartment of the wing disc, ectopic eye formation is seen at 100% penetrance, although the size of these ectopic eyes varies from disc to disc. When ciCe-2.Scer\UAS.T:Ivir\HA1 and hhScer\UAS.cAa co-expressed (driven by Scer\GAL4bi-omb-Gal4) in the wing disc leads to overgrowth and ectopic morphogenetic furrow initiation. When dppScer\UAS.cSa, hhScer\UAS.cAa and eyScer\UAS.cHa are co-expressed in clones (driven by Scer\GAL4Act5C.PI), very strong overgrowth and distorted morphology is seen in the wing disc. Co-expression of dppScer\UAS.cSa, hhScer\UAS.cAa and eyScer\UAS.cHa driven by Scer\GAL4bi-omb-Gal4, causes a high larval lethality at 25oC.
Co-expression of wgwg.3'UTR.Scer\UAS and hhScer\UAS.cAa under the control of Scer\GAL4dpp.blk1 does not rescue morphogenetic furrow progression from the posterior edge of the eye disc, but usually results in one (or occasionally more) ectopic morphogenetic furrows initiating in the interior of the eye primordium and progressing concentrically.
eyg1/Df(3L)iro-2 hemizygous eye discs completely lack photoreceptors. Photoreceptor development in these discs is not rescued by hhScer\UAS.cAa expressed under the control of Scer\GAL4dpp.PH. The lack of photoreceptor phenotype of eya1 eye discs is not rescued by hhScer\UAS.cAa expressed under the control of Scer\GAL4ey.PH.