FlyBase Allele Report: Dmel\shg[i.UAS.Tag:SS(aos),Tag:MYC]

General Information

Symbol

Dmel\shg^{i.UAS.Tag:SS(aos),Tag:MYC}

Species

D. melanogaster

Name

intracellular

FlyBase ID

FBal0057352

Feature type

allele

Associated gene

Dmel\shg

Associated Insertion(s)

Carried in Construct

P{UAS-shg.CADⁱ}

Also Known As

Cad^intra, UAS-Cadⁱ⁵

Key Links

Transgenic product class

dominant_negative_variant

(Sanson et al., 1996)

inframe_deletion

(Sanson et al., 1996)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

dominant_negative_variant

(Sanson et al., 1996)

inframe_deletion

(Sanson et al., 1996)

Mutagen

in vitro construct

(Sanson et al., 1996)

Progenitor genotype

shg^UAS.cSa

(Sanson et al., 1996)

Carried in construct

P{UAS-shg.CADⁱ}

Cytology

Description

UASt regulatory sequences drive expression of a dominant negative form of shg (consists of the C-terminal 208 amino acids, which encode the transmembrane and cytoplasmic domains). The protein is tagged at the N-terminal end with the Tag:SS(aos) signal sequence and is also tagged with Tag:MYC.

(Sanson et al., 1996)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Tagged with

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 1 )

Disease

Evidence

References

model of cancer

CEA

(Shen et al., 2014)

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

embryonic/first instar larval cuticle | dorsal, with Scer\GAL4^arm.PS

(Sanson et al., 1996)

epithelial cell | somatic clone | third instar larval stage, with Scer\GAL4^Act5C.PI

(Shen et al., 2014)

epithelial cell | third instar larval stage, with Scer\GAL4^dpp.PU

(Shen et al., 2014)

eye, with Scer\GAL4^GMR.PF

(Greaves et al., 1999)

head, with Scer\GAL4^VP16.arm

(Sanson et al., 1996)

interommatidial bristle | ectopic, with Scer\GAL4^GMR.PF

(Greaves et al., 1999)

microchaeta & mesothoracic tergum, with Scer\GAL4^pnr-MD237

(Renaud and Simpson, 2002)

microchaeta | supernumerary & mesothoracic tergum, with Scer\GAL4^pnr-MD237

(Renaud and Simpson, 2002)

ommatidium, with Scer\GAL4^GMR.PF

(Greaves et al., 1999)

posterior crossvein, with Scer\GAL4^en-e16E

(Greaves et al., 1999)

scutum, with Scer\GAL4^arm.PS

(Sanson et al., 1996)

wing, with Scer\GAL4^arm.PS

(Sanson et al., 1996)

wing, with Scer\GAL4^en-e16E

(Bauer et al., 2000)

wing | posterior, with Scer\GAL4^en-e16E

(Greaves et al., 1999)

wing blade, with Scer\GAL4^en.PU

(Mathew et al., 2011)

wing blade posterior compartment, with Scer\GAL4^en-e16E

(Sanson et al., 1996)

wing disc | somatic clone | third instar larval stage, with Scer\GAL4^Act5C.PI

(Shen et al., 2014)

wing disc | third instar larval stage, with Scer\GAL4^dpp.PU

(Shen et al., 2014)

wing margin, with Scer\GAL4^en-e16E

(Bauer et al., 2000)

wing margin, with Scer\GAL4^vg.PM

(Bajpai et al., 2004)

wing margin bristle, with Scer\GAL4^en-e16E

(Greaves et al., 1999)

Detailed Description

Statement

Reference

The expression of shg^{i.Scer\UAS.T:SS-aos,T:Hsap\MYC} under the control of Scer\GAL4^dpp.PU in third instar larval wing disc cells results in some expressing cells migrating and crossing the anterior-posterior compartment border; the clonal expression of shg^{i.Scer\UAS.T:SS-aos,T:Hsap\MYC} under the control of Scer\GAL4^Act5C.PI leads to expressing cells migrating and scattering across long distances in the wing disc, and frequently exhibiting long actin rich protrusions, as compared to controls.

(Shen et al., 2014)

Expression of aos::shg^{i.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^en.PU results in loss of wing blade.

(Mathew et al., 2011)

argos::shg^{i.Scer\UAS.T:Hsap\MYC}; Scer\GAL4^vg.PM flies have serrated wing margins.

(Bajpai et al., 2004)

When argos::shg^{i.Scer\UAS.T:Hsap\MYC} is driven by Scer\GAL4^pnr-MD237, abnormal patterning of the notal microchaetae is seen. Instead of being aligned in five straight rows, as seen in wild-type, they are arranged chaotically. The density of bristles is also increased. When argos::shg^{i.Scer\UAS.T:Hsap\MYC} is driven by Scer\GAL4^{neur-GAL4-A101} or Scer\GAL4^sca-537.4 no effect is seen on bristle pattern.

(Renaud and Simpson, 2002)

Overexpression of argos::shg^{i.Scer\UAS.T:Hsap\MYC} in all cells of the medial half of the notum, results in a slight decrease in bristle density.

(Renaud and Simpson, 2001)

When argos::shg^{i.Scer\UAS.T:Hsap\MYC} is driven by Scer\GAL4^en-e16E wing margin defects are seen in the adult wing.

(Bauer et al., 2000)

Expression of argos::shg^{i.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^en-e16E results in posterior wing notching, mimicking wg hypomorphic mutants. The strength of the wing notching phenotype caused by expression of argos::shg^{i.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^en-e16E varies depending on the particular P{UAS-shg.CADⁱ} insertion used. Flies carrying the P{UAS-shg.CADⁱ}10 insertion expressed under the control of Scer\GAL4^en-e16E always retain the posterior crossvein and a tuft of marginal bristles between the tips of wing veins 4 and 5, while these structures are consistently absent in flies carrying the P{UAS-shg.CADⁱ}5 insertion expressed under the control of Scer\GAL4^en-e16E. Expression of argos::shg^{i.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^GMR.PF results in rough eyes. Extra interommatidial bristles are produced and two bristles can often be seen originating from a single socket.

(Greaves et al., 1999)

Scer\GAL4^{arm.T:Hsim\VP16} mediated expression causes head and dorsal defects. Scer\GAL4^en-e16E mediated expression causes loss of wing margin in the posterior compartment. Scer\GAL4^arm.PS mediated expression causes defects in adult appendages; notum duplications or a drastic reduction of the wing to a tiny winglet.

(Sanson et al., 1996)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, enhanceable by wg[+]/wg^l-17

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, enhanceable by arm¹

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, enhanceable by arm²

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, enhanceable by dsh^b117

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, enhanceable by dsh^b117

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, enhanceable by dsh³

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, enhanceable by dsh³

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, enhanceable by wg^l-17

(Greaves et al., 1999)

NOT Enhanced by

Statement

Reference

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, non-enhanceable by kel^DE1

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, non-enhanceable by rho¹⁰

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, non-enhanceable by aos⁰⁰⁶

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, non-enhanceable by CadN^M19

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, non-enhanceable by Egfr^f3

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, non-enhanceable by CycA³

(Greaves et al., 1999)

Suppressed by

Statement

Reference

Scer\GAL4^en.PU, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, suppressible | partially by Traf4[+]/Traf4³

(Mathew et al., 2011)

Scer\GAL4^GMR.PF, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, suppressible by sgg^M11

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, suppressible by shg¹

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, suppressible by ft^G-rv

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, suppressible by ds⁵⁵

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, suppressible by lilli⁰⁰⁶³²

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, suppressible by l(2)dC9⁹

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, suppressible by l(3)09291⁰⁹²⁹¹

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, suppressible by Fas3^A183.1F2

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, suppressible by tws⁰¹⁴³⁶

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, suppressible by Scer\GAL4^GMR.PF/tyn^EP1421

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, suppressible by sgg^M11

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, suppressible by nkd²

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, suppressible by shg¹

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, suppressible by ft^G-rv

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, suppressible by ds⁵⁵

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, suppressible by crb^8F105

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, suppressible by sdt^EH681

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, suppressible by dlg1¹⁴

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, suppressible by stg²

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, suppressible by Cdk1^B47

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, suppressible by Df(3L)pbl-X1

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, suppressible by lilli⁰⁰⁶³²

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, suppressible by l(2)dC9⁹

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, suppressible by l(3)09291⁰⁹²⁹¹

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, suppressible by Fas3^A183.1F2

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, suppressible by tws⁰¹⁴³⁶

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, suppressible by Scer\GAL4^en-e16E/tyn^EP1421

(Greaves et al., 1999)

NOT suppressed by

Statement

Reference

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, non-suppressible by CadN^M19

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, non-suppressible by kel^DE1

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, non-suppressible by Hsap\JUP^UAS.cWa, Scer\GAL4^en-e16E

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, non-suppressible by Egfr^f3

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, non-suppressible by rho¹⁰

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, non-suppressible by aos⁰⁰⁶

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has visible phenotype, non-suppressible by CycA³

(Greaves et al., 1999)

NOT Suppressor of

Statement

Reference

shg^{i.UAS.Tag:SS(aos),Tag:MYC}, Scer\GAL4^Act5C.PI is a non-suppressor of neoplasia | somatic clone phenotype of Ras85D^V12.UAS, Scer\GAL4^Act5C.PI, scrib¹

(Pagliarini and Xu, 2003)

Phenotype Manifest In

Enhanced by

Statement

Reference

Scer\GAL4^vg.PM, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has wing margin phenotype, enhanceable by tws[+]/tws^j11C8

(Bajpai et al., 2004)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has wing margin phenotype, enhanceable by arm⁴

(Bauer et al., 2000)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has wing margin phenotype, enhanceable by pont^5.1

(Bauer et al., 2000)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has wing phenotype, enhanceable by arm¹

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has wing phenotype, enhanceable by arm²

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has wing phenotype, enhanceable by dsh^b117

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has wing phenotype, enhanceable by wg[+]/wg^l-17

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has eye phenotype, enhanceable by dsh^b117

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has eye phenotype, enhanceable by dsh³

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has wing phenotype, enhanceable by dsh³

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has eye phenotype, enhanceable by wg^l-17

(Greaves et al., 1999)

NOT Enhanced by

Statement

Reference

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has wing phenotype, non-enhanceable by CycA³

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has wing phenotype, non-enhanceable by kel^DE1

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has wing phenotype, non-enhanceable by rho¹⁰

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has wing phenotype, non-enhanceable by aos⁰⁰⁶

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has wing phenotype, non-enhanceable by CadN^M19

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has wing phenotype, non-enhanceable by Egfr^f3

(Greaves et al., 1999)

Suppressed by

Statement

Reference

Scer\GAL4^en.PU, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has wing blade phenotype, suppressible | partially by Traf4[+]/Traf4³

(Mathew et al., 2011)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has wing margin phenotype, suppressible by rept³⁵

(Bauer et al., 2000)

Scer\GAL4^GMR.PF, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has eye phenotype, suppressible by sgg^M11

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has eye phenotype, suppressible by shg¹

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has eye phenotype, suppressible by ft^G-rv

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has eye phenotype, suppressible by ds⁵⁵

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has eye phenotype, suppressible by lilli⁰⁰⁶³²

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has eye phenotype, suppressible by l(2)dC9⁹

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has eye phenotype, suppressible by l(3)09291⁰⁹²⁹¹

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has eye phenotype, suppressible by Fas3^A183.1F2

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has eye phenotype, suppressible by tws⁰¹⁴³⁶

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has eye phenotype, suppressible by Scer\GAL4^GMR.PF/tyn^EP1421

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has wing phenotype, suppressible by sgg^M11

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has wing phenotype, suppressible by nkd²

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has wing phenotype, suppressible by shg¹

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has wing phenotype, suppressible by ft^G-rv

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has wing phenotype, suppressible by ds⁵⁵

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has wing phenotype, suppressible by crb^8F105

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has wing phenotype, suppressible by sdt^EH681

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has wing phenotype, suppressible by dlg1¹⁴

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has wing phenotype, suppressible by stg²

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has wing phenotype, suppressible by Cdk1^B47

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has wing phenotype, suppressible by Df(3L)pbl-X1

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has wing phenotype, suppressible by lilli⁰⁰⁶³²

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has wing phenotype, suppressible by l(2)dC9⁹

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has wing phenotype, suppressible by l(3)09291⁰⁹²⁹¹

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has wing phenotype, suppressible by Fas3^A183.1F2

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has wing phenotype, suppressible by tws⁰¹⁴³⁶

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has wing phenotype, suppressible by Scer\GAL4^en-e16E/tyn^EP1421

(Greaves et al., 1999)

NOT suppressed by

Statement

Reference

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has wing phenotype, non-suppressible by aos⁰⁰⁶

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has wing phenotype, non-suppressible by CycA³

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has wing | posterior phenotype, non-suppressible by Hsap\JUP^UAS.cWa, Scer\GAL4^en-e16E

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has wing phenotype, non-suppressible by CadN^M19

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has wing phenotype, non-suppressible by kel^DE1

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has wing phenotype, non-suppressible by Egfr^f3

(Greaves et al., 1999)

Scer\GAL4^en-e16E, shg^{i.UAS.Tag:SS(aos),Tag:MYC} has wing phenotype, non-suppressible by rho¹⁰

(Greaves et al., 1999)

Enhancer of

Statement

Reference

Scer\GAL4^unspecified/shg^{i.UAS.Tag:SS(aos),Tag:MYC} is an enhancer of microchaeta phenotype of sca^BP2

(Renaud and Simpson, 2001)

Additional Comments

Genetic Interactions

Statement

Reference

The loss of wing blade caused by expression of aos::shg^{i.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^en.PU is partially suppressed by Traf4³/+.

(Mathew et al., 2011)

The severity of the serrated wing margin phenotype in argos::shg^{i.Scer\UAS.T:Hsap\MYC}; Scer\GAL4^vg.PM flies is enhanced by tws^j11C8/+.

(Bajpai et al., 2004)

The metastatic behaviour seen in clones in the eye disc which are homozygous for scrib¹ and are also expressing Ras85D^V12.Scer\UAS under the control of Scer\GAL4^Act5C.PI is not suppressed if they are co-expressing argos::shg^{i.Scer\UAS.T:Hsap\MYC}.

(Pagliarini and Xu, 2003)

Overexpression of argos::shg^{i.Scer\UAS.T:Hsap\MYC} in all cells of the medial half of the notum, results in a slight increase in bristle density in a sca^BP2 mutant background.

(Renaud and Simpson, 2001)

The addition of pont^5.1 enhances the wing margin phenotype seen in argos::shg^{i.Scer\UAS.T:Hsap\MYC}, Scer\GAL4^en-e16E flies. The addition of arm⁴ strongly enhances the wing margin phenotype seen in argos::shg^{i.Scer\UAS.T:Hsap\MYC}, Scer\GAL4^en-e16E flies. The addition of rept³⁵ suppresses the wing margin phenotype seen in argos::shg^{i.Scer\UAS.T:Hsap\MYC}, Scer\GAL4^en-e16E flies.

(Bauer et al., 2000)

The wing notching phenotype caused by expression of argos::shg^{i.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^en-e16E is enhanced by wg^l-17, arm¹, arm² or dsh^b117. The wing notching phenotype caused by expression of argos::shg^{i.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^en-e16E is suppressed by sgg^M11. The rough eye phenotype caused by expression of argos::shg^{i.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^GMR.PF is enhanced by wg^l-17 and dsh^b117 and suppressed by sgg^M11. The wing notching phenotype caused by expression of argos::shg^{i.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^en-e16E is rescued by co-expression of arm^{Δα.Scer\UAS} though not by co-expression of Hsap\JUP^Scer\UAS.cWa.

(Greaves et al., 1999)

Ectopic expression of arm^Scer\UAS.cSa rescues the wing defect caused by expression of argos::shg^{i.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^en-e16E to wild type. Loss of one copy of arm (arm¹) enhances the wing phenotype of surviving flies expressing argos::shg^{i.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^en-e16E, most die as pupae.

(Sanson et al., 1996)

Xenogenetic Interactions

Statement

Reference

The wing notching phenotype caused by expression of argos::shg^{i.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^en-e16E is not rescued by co-expression of Hsap\JUP^Scer\UAS.cWa.

(Greaves et al., 1999)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (9)

Reported As

Symbol Synonym

Cad^intra

(Mathew et al., 2011, Bajpai et al., 2004)

UASCad^intra

(Bauer et al., 2000)

aos::shg^{i.Scer\UAS.T:Hsap\MYC}

argos::shg^{i.Scer\UAS.T:Hsap\MYC}

argos::shg^i.UAS.T:Myc

gil::shg^i.UAS.T:Myc

shg^{i.Scer\UAS.T:SS-aos,T:Hsap\MYC}

shg^{i.UAS.Tag:SS(aos),Tag:MYC}

Name Synonyms

intracellular

(Sanson et al., 1996)

Secondary FlyBase IDs

References (13)

Report Sections

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