|Feature type||allele||Associated gene||Dmel\arm|
|Also Known As||ArmS12|
|Mutagen||in vitro construct - site directed mutagenesis, in vitro construct - deletion|
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|Nature of the Allele|
|Mutations Mapped to the Genome|
|Associated Sequence Data|
|Nature of the lesion|
Alteration of repeat 1.
Construct: Amino acids 549-606 are deleted (fusion of repeats 10 and 11 and deletion of the insertion between these repeats).
|Carried in construct|
|Phenotype Manifest In|
Embryos expressing armS12.T:Hsap\MYC in a arm4 background have a "lawn of denticles" cuticle phenotype.
Many photoreceptors are rescued from death in ApcQ8 homozygotes carrying one copy of armS12.T:Hsap\MYC in an arm4/+ background.
Embryos exhibit very weak segment polarity defects, adherens junctions are normal.
|Phenotype Manifest In|
arm4, armS12.T:Hsap\MYC has denticle | ectopic phenotype, suppressible | partially by pan::pygopygoΔPHD-ΔNTCF.Scer\UAS.T:Ivir\HA1/Scer\GAL4arm.PS
The "lawn of denticles" cuticle phenotype seen in embryos carrying armS12.T:Hsap\MYC in an arm4 background is substantially rescued by expression of pan::pygopygoΔPHD-ΔNTCF.Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4arm.PS; a segmented pattern of denticle bands and naked cuticle is restored.
|Complementation & Rescue Data|
|Not rescued by|
The "lawn of denticles" cuticle phenotype seen in embryos carrying armS12.T:Hsap\MYC in an arm4 background is not rescued by ubiquitous expression of armScer\UAS.T:sev-TM using Scer\GAL4arm.PS. Ubiquitous expression of armS10.Scer\UAS.T:Hsap\MYC using Scer\GAL4arm.PS produces ectopic naked cuticle in embryos carrying armS12.T:Hsap\MYC in an arm4 background.
|Stocks ( 0 )|
|Notes on Origin|
|External Crossreferences & Linkouts|
|Synonyms & Secondary IDs ( 5 )|
|Secondary FlyBase IDs|
|References ( 4 )|