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General Information
Symbol
Dmel\aopunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0057903
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference
    Homozygous clones in the eye result in patches of necrotic tissue, naked cuticle lacking photoreceptors and tubular outgrowths. In homozygous clones in the eye disc, cells remain apically constricted several rows posterior to the morphogenetic furrow, in contrast to wild type. The clones are not rounded, but they segregate away from neighbouring wild-type cells as they remain in the lower plane of the morphogenetic furrow.
    aopunspecified embryos have an average of 5.3 +/- 0.10 neurons per lch5 organ.
    aopunspecified/Df(2L)dp-79b and homozygous embryos have ectopic denticles immediately anterior to the denticle belts.
    Homozygotes have an excess of R7-like central photoreceptors.
    Homozygous embryos have an anterior dorsal hole in the epidermis, and brain and sometimes gut extrude through this hole. Head involution is normal. The defects are visible during dorsal closure.
    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Suppressed by
    Enhancer of
    Statement
    Reference
    aopunspecified/aop[+] is an enhancer of visible phenotype of Ras85DV12.sev
    Suppressor of
    Statement
    Reference
    aopunspecified/aop[+] is a suppressor of lethal phenotype of Raf12
    aopunspecified/aop[+] is a suppressor of visible phenotype of ksr::torΔNksr.hs.sev
    Phenotype Manifest In
    Suppressed by
    Enhancer of
    Statement
    Reference
    aopunspecified/aop[+] is an enhancer of eye phenotype of Ras85DV12.sev
    Suppressor of
    Statement
    Reference
    Additional Comments
    Genetic Interactions
    Statement
    Reference
    The apical constriction phenotype seen posterior to the morphogenetic furrow in aopunspecified clones in the eye disc is suppressed if the clones express either panΔN.Scer\UAS or AxnScer\UAS.T:Avic\GFP under the control of Scer\GAL4unspecified. The adult eye defects caused by homozygous aopunspecified clones are also suppressed if the clones express either panΔN.Scer\UAS or AxnScer\UAS.T:Avic\GFP under the control of Scer\GAL4unspecified.
    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    aopunspecified
    Name Synonyms
    Secondary FlyBase IDs
      References (7)