Allele Scer\GAL4^sca-4512

General Information
Symbol	Scer\GAL4^sca-4512	Species	S. cerevisiae
Name		FlyBase ID	FBal0058757
Feature type	allele	Associated gene	Scer\GAL4

Allele class
Mutagen	P-element activity
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	P-element activity (Huang and Fischer-Vize, 1996)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Caused by insertion	P{GAL4}sca⁴⁵¹² (Huang and Fischer-Vize, 1996, De Iaco et al., 2006, Cleary and Doe, 2006, Kammerer and Giangrande, 2001, McGovern et al., 2003, Mistry et al., 2004, Miller et al., 1998, Ragone et al., 2001, Bernardoni et al., 1998, Skeath and Doe, 1996)
Cytology
Phenotypic Data
Phenotypic Class
	increased cell death, with CG11966^GS-A304 (McGovern et al., 2003) lethal, with CG9650^EP1617 (McGovern et al., 2003) lethal, with CG11966^GS-A304 (McGovern et al., 2003) lethal, with Cnx99A^EP3522 (McGovern et al., 2003) lethal, with CycE^GS-A117 (McGovern et al., 2003) lethal, with CycE^GS-M986 (McGovern et al., 2003) lethal, with dpp^EP2232 (McGovern et al., 2003) lethal, with GS(2)A096^GS-A096 (McGovern et al., 2003) lethal, with hh^EP3521 (McGovern et al., 2003) lethal, with hkb^GS-M962 (McGovern et al., 2003) lethal, with hkb^GS-M1423b (McGovern et al., 2003) lethal, with Kr-h1^EP2289 (McGovern et al., 2003) lethal, with Kr-h1^GS-A029 (McGovern et al., 2003) lethal, with salm^GS-A265c (McGovern et al., 2003) lethal, with sqz^GS-M1168 (McGovern et al., 2003) neuroanatomy defective, with Kr^Scer\UAS.cHa (Cleary and Doe, 2006) partially lethal - majority die, with CycE^GS-A095 (McGovern et al., 2003) partially lethal - majority die, with lea^EP2582 (McGovern et al., 2003) partially lethal - majority die, with stg^GS-M1565 (McGovern et al., 2003) viable, with drl^EP2076 (McGovern et al., 2003) viable, with Egfr^EPM865 (McGovern et al., 2003) viable, with rho^EP3704 (McGovern et al., 2003) viable, with RhoGEF64C^EP3035 (McGovern et al., 2003) viable, with RhoGEF64C^EP3322 (McGovern et al., 2003) viable, with stg^EP3426 (McGovern et al., 2003) viable, with stg^EP3432 (McGovern et al., 2003) visible, with Cul-3^Scer\UAS.cMa (Mistry et al., 2004)
Phenotype Manifest In
	eye, with Egfr^EPM865 (McGovern et al., 2003) glial cell \| ectopic, with gcm2^Scer\UAS.cKa (Kammerer and Giangrande, 2001) intermediate longitudinal fascicle, with Cnx99A^EP3522 (McGovern et al., 2003) lateral longitudinal fascicle, with GS(2)A096^GS-A096 (McGovern et al., 2003) longitudinal connective, with CG9650^EP1617 (McGovern et al., 2003) longitudinal connective, with dpp^EP2232 (McGovern et al., 2003) longitudinal connective, with drl^EP2076 (McGovern et al., 2003) longitudinal connective, with EP-M269^EP-M269 (McGovern et al., 2003) longitudinal connective, with GS(2)A096^GS-A096 (McGovern et al., 2003) longitudinal connective, with hkb^GS-M962 (McGovern et al., 2003) longitudinal connective, with hkb^GS-M1423b (McGovern et al., 2003) longitudinal connective, with sqz^GS-M1168 (McGovern et al., 2003) longitudinal connective, with stg^GS-M1565 (McGovern et al., 2003) macrochaeta, with CycE^GS-A095 (McGovern et al., 2003) macrochaeta, with stg^GS-M1565 (McGovern et al., 2003) medial longitudinal fascicle, with Cnx99A^EP3522 (McGovern et al., 2003) mesothoracic tergum & macrochaeta, with Cul-3^Scer\UAS.cMa (Mistry et al., 2004) neuroblast NB6-4 of thorax, with gcm^Scer\UAS.cBa (Ragone et al., 2001) ommatidium, with Egfr^EPM865 (McGovern et al., 2003) RP1 motor neuron, with GS(2)A096^GS-A096 (McGovern et al., 2003) scutellum & macrochaeta, with Cul-3^Scer\UAS.cMa (Mistry et al., 2004) sensillum campaniformium & wing, with Cul-3^Scer\UAS.cMa (Mistry et al., 2004) subperineurial glial cell \| supernumerary, with gcm^Scer\UAS.cBa (De Iaco et al., 2006) subperineurial glial cell \| supernumerary, with hkb^Scer\UAS.cMa (De Iaco et al., 2006) U3 neuron \| ectopic, with Kr^Scer\UAS.cHa (Cleary and Doe, 2006) ventral midline, with CG11966^GS-A304 (McGovern et al., 2003) ventral nerve cord, with CG11966^GS-A304 (McGovern et al., 2003) ventral nerve cord, with Cnx99A^EP3522 (McGovern et al., 2003) ventral nerve cord commissure, with CG9650^EP1617 (McGovern et al., 2003) ventral nerve cord commissure, with CG11966^GS-A304 (McGovern et al., 2003) ventral nerve cord commissure, with Cnx99A^EP3522 (McGovern et al., 2003) ventral nerve cord commissure, with CycE^GS-A095 (McGovern et al., 2003) ventral nerve cord commissure, with CycE^GS-A117 (McGovern et al., 2003) ventral nerve cord commissure, with CycE^GS-M986 (McGovern et al., 2003) ventral nerve cord commissure, with dpp^EP2232 (McGovern et al., 2003) ventral nerve cord commissure, with drl^EP2076 (McGovern et al., 2003) ventral nerve cord commissure, with Egfr^EPM865 (McGovern et al., 2003) ventral nerve cord commissure, with EP-M269^EP-M269 (McGovern et al., 2003) ventral nerve cord commissure, with GS(2)A096^GS-A096 (McGovern et al., 2003) ventral nerve cord commissure, with hh^EP3521 (McGovern et al., 2003) ventral nerve cord commissure, with hkb^GS-M962 (McGovern et al., 2003) ventral nerve cord commissure, with hkb^GS-M1423b (McGovern et al., 2003) ventral nerve cord commissure, with Kr-h1^EP2289 (McGovern et al., 2003) ventral nerve cord commissure, with Kr-h1^GS-A029 (McGovern et al., 2003) ventral nerve cord commissure, with lea^EP2582 (McGovern et al., 2003) ventral nerve cord commissure, with rho^EP3704 (McGovern et al., 2003) ventral nerve cord commissure, with RhoGEF64C^EP3035 (McGovern et al., 2003) ventral nerve cord commissure, with RhoGEF64C^EP3322 (McGovern et al., 2003) ventral nerve cord commissure, with salm^GS-A265c (McGovern et al., 2003) ventral nerve cord commissure, with sqz^GS-M1168 (McGovern et al., 2003) ventral nerve cord commissure, with stg^EP3426 (McGovern et al., 2003) ventral nerve cord commissure, with stg^EP3432 (McGovern et al., 2003) ventral nerve cord commissure, with stg^GS-M1565 (McGovern et al., 2003) wing margin bristle, with Cul-3^Scer\UAS.cMa (Mistry et al., 2004)
Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhanced by
Statement Reference Scer\GAL4^sca-4512, gcm^Scer\UAS.cBa has subperineurial glial cell \| supernumerary phenotype, enhanceable by Scer\GAL4^sca-4512/hkb^Scer\UAS.cMa (De Iaco et al., 2006, De Iaco et al., 2006) Scer\GAL4^sca-4512, hkb^Scer\UAS.cMa has subperineurial glial cell \| supernumerary phenotype, enhanceable by gcm^Scer\UAS.cBa/Scer\GAL4^sca-4512 (De Iaco et al., 2006, De Iaco et al., 2006)
Enhancer of
Statement Reference gcm^Scer\UAS.cBa/Scer\GAL4^sca-4512 is an enhancer of subperineurial glial cell \| supernumerary phenotype of Scer\GAL4^sca-4512, hkb^Scer\UAS.cMa (De Iaco et al., 2006, De Iaco et al., 2006) Scer\GAL4^sca-4512/hkb^Scer\UAS.cMa is an enhancer of subperineurial glial cell \| supernumerary phenotype of Scer\GAL4^sca-4512, gcm^Scer\UAS.cBa (De Iaco et al., 2006, De Iaco et al., 2006)
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Rescues	Scer\GAL4^sca-4512/sc^Scer\UAS.cHa rescues In(1)y^3PLsc^8R (Skeath and Doe, 1996)
Fails to rescue	faf^Scer\UAS.cHa/Scer\GAL4^sca-4512 fails to rescue faf^BX4 (Huang and Fischer-Vize, 1996)
Comments
Stocks ( 0 )

Notes on Origin
Discoverer	M. Mlodzik

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	GAL4^sca-4512 Scer\GAL4^sca-4512
Name Synonym
Secondary FlyBase IDs

References ( 10 )
Research paper	Cleary and Doe, 2006, Genes Dev. 20(4): 429--434 Regulation of neuroblast competence: multiple temporal identity factors specify distinct neuronal fates within a single early competence window. [FBrf0190540] De Iaco et al., 2006, EMBO J. 25(1): 244--254 Huckebein-mediated autoregulation of Glide/Gcm triggers glia specification. [FBrf0190357] Mistry et al., 2004, Mech. Dev. 121(12): 1495--1507 Cullin-3 regulates pattern formation, external sensory organ development and cell survival during Drosophila development. [FBrf0180486] McGovern et al., 2003, Mech. Dev. 120(10): 1193--1207 A targeted gain of function screen in the embryonic CNS of Drosophila. [FBrf0167840] Kammerer and Giangrande, 2001, EMBO J. 20(17): 4664--4673 Glide2, a second glial promoting factor in Drosophila melanogaster. [FBrf0138381] Ragone et al., 2001, Dev. Biol. 235(1): 74--85 A novel mode of asymmetric division identifies the fly neuroglioblast 6-4T. [FBrf0137378] Bernardoni et al., 1998, Development 125(16): 3189--3200 Glial differentiation does not require a neural ground state. [FBrf0104717] Miller et al., 1998, EMBO J. 17(21): 6316--6326 Positive autoregulation of the glial promoting factor glide/gcm. [FBrf0105383] Huang and Fischer-Vize, 1996, Development 122(10): 3207--3216 Undifferentiated cells in the developing Drosophila eye influence facet assembly and require the Fat facets ubiquitin-specific protease. [FBrf0090618] Skeath and Doe, 1996, Curr. Biol. 6(9): 1146--1152 The achaete-scute complex proneural genes contribute to neural precursor specification in the Drosophila CNS. [FBrf0090800]

Allele Scer\GAL4sca-4512

Allele Scer\GAL4^sca-4512