FlyBase Allele Report: Scer\GAL4[cad-em459]

General Information

Symbol

Scer\GAL4^cad-em459

Species

S. cerevisiae

Name

FlyBase ID

FBal0058761

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

P{GawB}cad^em459

Carried in Construct

Also Known As

cad-GAL4, caudal-Gal4

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Associated Insertion(s)

P{GawB}cad^em459

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{GawB}

enhancer trap

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

No Assay Recorded

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage

parasegment 15

(Calleja et al., 1996)

pupal stage & adult stage

analia

(Calleja et al., 1996)

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 13 -- 17

parasegment 15

(Calleja et al., 1996)

larval stage

hindgut

(Gorfinkiel et al., 1999)

genital disc

(Gorfinkiel et al., 1999)

Additional Information

Statement

Reference

Larval expression is observed in the presumptive cells of both the hindgut and the analia.

(Gorfinkiel et al., 1999)

Expression restricted to PS15 (in embryos) or analia (in adults). Observed as y⁺ phenotype in adults; expression assumed to be earlier.

(Calleja et al., 1996)

Marker for

Reflects expression of

cad

(Gorfinkiel et al., 1999, Calleja et al., 1996)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal immune response, with Duox^RNAi.UAS

(Ha et al., 2005, Ha et al., 2005)

abnormal immune response, with Irc^RNAi.UAS

(Ha et al., 2005)

decreased occurrence of cell division | larval stage, with Rcom\RT^A.UAS

(Gorfinkiel et al., 2003)

decreased occurrence of cell division | larval stage, with Rcom\RT^A-cs2.UAS

(Gorfinkiel et al., 2003)

visible, with ci^UAS.cAa

(Moreno and Morata, 1999)

visible, with dpp^UAS.cCa

(Gorfinkiel et al., 2003)

visible, with tkv^{Q253D.UAS.cNb}

(Gorfinkiel et al., 2003)

visible, with wg^UAS.cLa

(Gorfinkiel et al., 2003)

Phenotype Manifest In

adult hindgut, with ci^UAS.cAa

(Moreno and Morata, 1999)

adult hindgut, with Dll^UAS.cGa

(Gorfinkiel et al., 1999)

adult posterior midgut epithelium, with cad^RNAi.397.UAS

(Ryu et al., 2008)

aedeagus | increased number, with wg^UAS.cLa

(Gorfinkiel et al., 2003)

analia, with tkv^{Q253D.UAS.cNb}

(Gorfinkiel et al., 2003)

analia, with y^UAS.cCa

(Calleja et al., 1996)

analia | precursor, with Dll^UAS.cGa

(Gorfinkiel et al., 1999)

cercus, with ci^UAS.cAa

(Moreno and Morata, 1999)

cercus, with ci^UAS.Tag:HA

(Gorfinkiel et al., 1999)

cercus, with Dll^UAS.cGa

(Gorfinkiel et al., 1999)

embryonic primordium of adult hindgut precursor, with eve^UAS.cBa

(Gorfinkiel et al., 1999)

female genital disc, with hh^UAS.cCa

(Gorfinkiel et al., 2003)

female genitalia | increased number, with hh^UAS.cCa

(Gorfinkiel et al., 2003)

genital disc, with Rcom\RT^A.UAS

(Gorfinkiel et al., 2003)

genitalia, with tkv^{Q253D.UAS.cNb}

(Gorfinkiel et al., 2003)

hypogynium | increased number, with dpp^UAS.cCa

(Gorfinkiel et al., 2003)

male genital disc, with hh^UAS.cCa

(Gorfinkiel et al., 2003)

male genitalia | increased number, with hh^UAS.cCa

(Gorfinkiel et al., 2003)

terminalia, with dpp^UAS.cCa

(Gorfinkiel et al., 2003)

terminalia, with Rcom\RT^A.UAS

(Gorfinkiel et al., 2003)

terminalia, with wg^UAS.cLa

(Gorfinkiel et al., 2003)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Irc^RNAi.UAS, Scer\GAL4^cad-em459 has abnormal immune response phenotype, suppressible by Duox^RNAi.UAS, Scer\GAL4^cad-em459

(Ha et al., 2005)

Duox^RNAi.UAS, Scer\GAL4^cad-em459 has abnormal immune response phenotype, suppressible by Irc^RNAi.UAS, Scer\GAL4^cad-em459

(Ha et al., 2005)

Duox^RNAi.UAS, Scer\GAL4^cad-em459 has abnormal immune response phenotype, suppressible by Hsap\DUOX1^UAS.cHa, Scer\GAL4^cad-em459

(Ha et al., 2005)

Duox^RNAi.UAS, Scer\GAL4^cad-em459 has abnormal immune response phenotype, suppressible by Hsap\DUOX2^UAS.cHa, Scer\GAL4^cad-em459

(Ha et al., 2005)

Suppressor of

Statement

Reference

CecA1^UAS.cRa/Scer\GAL4^cad-em459 is a suppressor of abnormal immune response phenotype of Dredd^B118

(Ryu et al., 2006)

Duox^RNAi.UAS, Scer\GAL4^cad-em459 is a suppressor of abnormal immune response phenotype of Irc^RNAi.UAS, Scer\GAL4^cad-em459

(Ha et al., 2005)

Irc^RNAi.UAS, Scer\GAL4^cad-em459 is a suppressor of abnormal immune response phenotype of Duox^RNAi.UAS, Scer\GAL4^cad-em459

(Ha et al., 2005)

Hsap\DUOX1^UAS.cHa, Scer\GAL4^cad-em459 is a suppressor of abnormal immune response phenotype of Duox^RNAi.UAS, Scer\GAL4^cad-em459

(Ha et al., 2005)

Hsap\DUOX2^UAS.cHa, Scer\GAL4^cad-em459 is a suppressor of abnormal immune response phenotype of Duox^RNAi.UAS, Scer\GAL4^cad-em459

(Ha et al., 2005)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Duox^UAS.cHa/Scer\GAL4^cad-em459 rescues Duox^RNAi.UAS

(Ha et al., 2005)

Partially rescues

Rel^{UAS.Tag:polyHis}/Scer\GAL4^cad-em459 partially rescues Rel^E20

(Ryu et al., 2006)

wg^UAS.cLa/Scer\GAL4^cad-em459 partially rescues wg^Sp-1/wg^l-16

(Gorfinkiel et al., 2003)

Fails to rescue

MAPk-Ak2^UAS.cSa/Scer\GAL4^cad-em459 fails to rescue MAPk-Ak2^Δ43

(Seisenbacher et al., 2011)

Duox^ΔPHD.UAS/Scer\GAL4^cad-em459 fails to rescue Duox^RNAi.UAS

(Ha et al., 2005)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

GAL4^cad-em459

Scer\GAL4^cad-em459

Name Synonyms

Secondary FlyBase IDs

References (14)

Report Sections

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