Co-expression of PdfrScer\UAS.cMa fully rescues the response of the M pacemaker neurons in the brain to Pdf to wild-type levels in flies expressing G-sα60AScer\UAS.cCa under the control of Scer\GAL4P2.4.Pdf.
Co-expression of Dh31-R1Scer\UAS.cDa fully rescues the response of the M pacemaker neurons in the brain to Dh31 to wild-type levels in flies expressing G-sα60AScer\UAS.cCa under the control of Scer\GAL4P2.4.Pdf.
Co-expression of Gr21aScer\UAS.cKa and Gr63aScer\UAS.cKa under the control of Scer\GAL4Or22a.8010 in the "empty neuron" system ("Δhalo" embryos - Dp(2;2)dppd21 + Df(2L)dp-79b - in which Or22a and Or22b are deleted) confers a modest response to CO[] in the ab3A olfactory receptor neuron (ORN). Additional co-expression of G-sα60AScer\UAS.cCa does not increase the response of the ab3A ORN to CO[].
Animals co-expressing G-sα60AScer\UAS.cCa and AdoRScer\UAS.cDa under the control of Scer\GAL4en-e16E show 20% lethality as pharate adults, whereas expression of either G-sα60AScer\UAS.cCa or AdoRScer\UAS.cDa alone under the control of Scer\GAL4en-e16E does not cause lethality. The flies that do emerge show strong wing deformation and melanisation.
Expression of G-sα60AScer\UAS.cCa under the control of Scer\GAL4Orco.T:Hsim\VP16 in homozygous G-sα60AR60 ab3A olfactory receptor neurons rescues the reduced odour response seen in these neurons at near saturating concentrations of either methyl butyrate or butyric acid.
Stimulation of long labellar taste bristles in G-sα60AR19/Scer\GAL4Tre.PU; G-sα60AScer\UAS.cCa flies with trehalose induces significantly more biphasic spikes in associated sensory neurons than seen in G-sα60AR19/+ flies but not significantly more than that seen in wild-type flies.
When G-sα60AScer\UAS.cCa is driven by Scer\GAL4B185 the synaptic bouton and the late larval lethality phenotypes of G-sα60AB19 homozygotes. When driven by Scer\GAL4C380 or Scer\GAL4elav.PLu the neuromuscular junction phenotypes are rescued to wild-type. When driven by Scer\GAL4C57 or Scer\GAL4Mhc.PW in muscles, the defects in bouton formation is rescued, while the branching defects are only partially rescued.