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General Information
Symbol
Dmel\EgfrWT.hs
Species
D. melanogaster
Name
FlyBase ID
FBal0058984
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

Contains a type II Egfr cDNA (containing the distal alternative 5' exon) encoding the four exons from the 5' end of the Egfr gene fused to a genomic Egfr fragment encoding the 3' large exon and 3' non-coding sequences. This construct is expressed under the control of an Hsp70 promoter.

Allele components
Product class / Tool use(s)
Regulatory region(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Other
Statement
Reference
Phenotype Manifest In
Enhancer of
Statement
Reference
Suppressor of
Statement
Reference

EgfrWT.hs is a suppressor of wing vein phenotype of aoshs.PF

Additional Comments
Genetic Interactions
Statement
Reference

EgfrWT.hs is lethal in a vapKS67 homozygous background.

EgfrWT.hs/+ suppresses the wing-vein loss phenotype of argoshs.PF/+ animals heat-shocked at 34oC.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

Carried in a plasmid, transfected into S2 cells and used in immunoprecipitation assays.

Carried in plasmid "pDER", transfected into Schneider 2 cells and used in autophosphorylation assays.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
EgfrWT.hs
Name Synonyms
Secondary FlyBase IDs
    References (4)