FlyBase Allele Report: Dmel\CycE[UAS.cLa]

The expression of CycE^UAS.cLa for 3 days during larval development under the combined control of Scer\GAL4^ap-md544 and Gal80[ts] induces abundant apoptosis (TUNEL assay) and an increased DNA damage response (phospho-H2Av) in third instar larval wing discs.

(Murcia et al., 2019)

Larval brains expressing CycE^Scer\UAS.cLa under the control of Scer\GAL4^insc-Mz1407 do not show any significant change in the nucleolar size of immature secondary neuroblasts, as compared to controls.

(Wu et al., 2017)

Expression of CycE^Scer\UAS.cLa under the control of Scer\GAL4^salm.EPv has no effect on wing or wing cell size.

(Barrios et al., 2015)

Scer\GAL4^en.PU-mediated expression reduces the fraction of wing disc cells in G1 phase and concomitantly increases the fraction in G2.

(Zielke et al., 2014)

Expression of CycE^Scer\UAS.cLa under the control of Scer\GAL4^en-e16E results in a drastic lowering of the number of cells in G[[1]] phase and an increase in the number of cells in S phase compared to controls, while the overall length of the cell cycle is similar to controls.

(Faradji et al., 2011)

Expression of CycE^Scer\UAS.cLa under the control of Scer\GAL4^en-e16E has no effect on the posterior wing compartment.

(Wang et al., 2008)

Expression of CycE^Scer\UAS.cLa under the control of Scer\GAL4^en-e16E induces cells in the posterior compartment cells of stage 12 embryos to enter S phase and divide, resulting in 59 cells per posterior compartment on average as opposed to the wild-type number of 44. These cells are of a smaller size than wild-type cells. However, there is also an increase in the number of posterior compartment cells undergoing apoptosis and most cell death occurs at the front of the posterior compartment. At the larval stage, posterior compartment size is similar to wild type.

(Parker, 2006)

BrdU incorporation shows that the G1-phase of pIIIb cells expressing CycE^Scer\UAS.cLa under the control of Scer\GAL4^neur-P72 is shorter than in wild-type cells. However, no BrdU incorporation is observed in the sibling glial cells. At 20 hours APF, the shaft and socket cells of Scer\GAL4^neur-P72>CycE^Scer\UAS.cLa animals incorporate BrdU, while wild-type shaft and socket cells show no such incorporation.

(Audibert et al., 2005)

Expression of CycE^Scer\UAS.cLa under the control of Scer\GAL4^GMR.PF produces excess mitoses in the eye disc.

(Baonza and Freeman, 2005)

Expression of CycE^Scer\UAS.cLa under the regulation of Scer\GAL4^sca-537.4 in the neuroectoderm results in an increase in the number of cells in the NB6-4a lineage (up to five cells) at approximately stages 11-14. Some of these cells migrate medially, as NB6-4 glial cells normally do (and express glial-specific markers), while others stay in a dorso-lateral position and express neuronal markers, suggesting a neuronal identity. In addition, overexpression results in transformation of NB6-4a to NB6-4t in 40% of embryos. Expression of CycE^Scer\UAS.cLa under the regulation of Scer\GAL4^sca-537.4 in the neuroectoderm results in an increase in the number of cells in the NB6-4a lineage (up to five cells) at approximately stages 11-14. Some of these cells migrate medially and express glial-specific markers, as NB6-4a cells normally do, while others stay in a dorso-lateral position and express neuronal markers. In addition, overexpression results in transformation of NB6-4a to NB6-4t in 40% of embryos. This phenotype is cell-autonomous: single NB6-4a cells tranplanted from CycE^Scer\UAS.cLa; Scer\GAL4^sca-537.4 to wild type embryos still make neurons as well as glial cells.

(Berger et al., 2005)

The salivary glands of CycE^Scer\UAS.cLa; Scer\GAL4^ptc-559.1 larvae are small and their cells do not have endoreplicated DNA.

(Pierce et al., 2004)

Ovarian follicle cells in somatic clones of CycE^Scer\UAS.cLa; Scer\GAL4^Act5C.PP after stage 6 of oogenesis have small nuclei and do not incorporate BrdU indicating a lack of S phases.

(Shcherbata et al., 2004)

Expression of CycE^Scer\UAS.cLa under the control of Scer\GAL4^ptc-559.1 in the wing results in a slight increase in cell number.

(Pielage et al., 2003)

When CycE^Scer\UAS.cLa is driven by Scer\GAL4^bi-omb-Gal4 glial cells in the eye disc undergo excessive proliferation. However these glial cells never cross the axonal boundary.

(Rangarajan et al., 2001)

Expression of CycE^Scer\UAS.cLa under the control of Scer\GAL4^ey.PH has no effect on eye size.

(Tapon et al., 2001)

When CycE^Scer\UAS.cLa is driven by Scer\GAL4^GMR.PF, and the cells of the eye disc analysed using FACS analysis, a slight decrease in cell size is seen.

(Datar et al., 2000)

When expression is driven by Scer\GAL4^en-e16E, no phenotype is detectable in the wing.

(Sotillos and Campuzano, 2000)

Almost no cells are in G1 in wing discs expressing CycE^Scer\UAS.cLa under the control of Scer\GAL4^en-e16E, in contrast to wild-type wing discs. The number of posterior cells and the size of the posterior compartment in these wing discs is not significantly different from wild-type. The average duration of cell cycle phases in wing disc cells expressing CycE^Scer\UAS.cLa under the control of Scer\GAL4^Act5C.PP is: G1 = 0.6 hours, S = 6.8 hours and G2 = 3.8 hours (wild-type values are G1 = 3.4 hours, S = 4.4 hours and G2 = 4.2 hours).

(Neufeld et al., 1998)

Scer\GAL4^F4-mediated expression causes small nuclei in the third instar salivary glands: inhibition of endoreplication and growth, preceded initially by an ectopic S phase occurring just after the onset of ectopic CycE expression. Expression has no effect on adult viability.

(Weiss et al., 1998)

External Data

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Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

CycE^UAS.cLa, Scer\GAL4^en-e16E has increased cell death | embryonic stage phenotype, enhanceable by Egfr^DN.UAS, Scer\GAL4^en-e16E

(Parker, 2006)

CycE^UAS.cLa, Scer\GAL4^en-e16E has increased cell death | embryonic stage phenotype, enhanceable by spi¹

(Parker, 2006)

CycE^UAS.cLa has increased cell number | embryonic stage phenotype, enhanceable by Scer\GAL4^en-e16E/BacA\p35^UAS.cHa

(Parker, 2006)

CycE^UAS.cLa has decreased cell size | embryonic stage phenotype, enhanceable by Scer\GAL4^en-e16E/BacA\p35^UAS.cHa

(Parker, 2006)

Suppressed by

Statement

Reference

CycE^UAS.cLa, Scer\GAL4^en-e16E has increased cell death | embryonic stage phenotype, suppressible | partially by Df(3L)XR38

(Parker, 2006)

CycE^UAS.cLa, Scer\GAL4^en-e16E has increased cell death | embryonic stage phenotype, suppressible by Egfr::tor^act.UAS, Scer\GAL4^en-e16E

(Parker, 2006)

CycE^UAS.cLa, Scer\GAL4^en-e16E has increased cell death | embryonic stage phenotype, suppressible by Ras85D^V12.UAS, Scer\GAL4^en-e16E

(Parker, 2006)

CycE^UAS.cLa has increased cell death | embryonic stage phenotype, suppressible by Scer\GAL4^en-e16E/BacA\p35^UAS.cHa

(Parker, 2006)

CycE^UAS.cLa, Scer\GAL4^en-e16E has increased cell death | embryonic stage phenotype, suppressible by hid⁰⁵⁰¹⁴

(Parker, 2006)

CycE^UAS.cLa, Scer\GAL4^neur-P72 has decreased occurrence of cell division phenotype, suppressible by dap[+]/dap⁴

(Audibert et al., 2005)

NOT suppressed by

Statement

Reference

CycE^UAS.cLa, Scer\GAL4^Act5C.PP has abnormal endomitotic cell cycle | somatic clone phenotype, non-suppressible by geminin^RNAi.UAS, Scer\GAL4^Act5C.PP

(Narbonne-Reveau et al., 2008)

CycA^UAS.cWa, CycE^UAS.cLa, Scer\GAL4^GMR.PF has increased occurrence of cell division | larval stage phenotype, non-suppressible by Delta^UAS.cJa, Scer\GAL4^GMR.PF

(Baonza and Freeman, 2005)

Enhancer of

Statement

Reference

CycE^UAS.cLa, Scer\GAL4^GMR.PF is an enhancer of visible phenotype of Hsap\MAPT^{S202A.T205A.UAS}, Scer\GAL4^GMR.PF

(Steinhilb et al., 2007)

CycE^UAS.cLa, Scer\GAL4^GMR.PF is an enhancer of visible phenotype of Hsap\MAPT^{T231A.S235A.UAS}, Scer\GAL4^GMR.PF

(Steinhilb et al., 2007)

CycE^UAS.cLa, Scer\GAL4^GMR.PF is an enhancer of visible phenotype of Hsap\MAPT^{S396A.S404A.UAS}, Scer\GAL4^GMR.PF

(Steinhilb et al., 2007)

CycE^UAS.cLa, Scer\GAL4^GMR.PF is an enhancer of visible phenotype of Hsap\MAPT^UAS.cWa, Scer\GAL4^GMR.PF

(Steinhilb et al., 2007)

CycE^UAS.cLa, Scer\GAL4^ptc-559.1 is an enhancer of decreased cell number phenotype of Scer\GAL4^ptc-559.1, dlt^RNAi.UAS

(Pielage et al., 2003)

NOT Enhancer of

Statement

Reference

CycE^UAS.cLa, Scer\GAL4^insc-Mz1407 is a non-enhancer of abnormal neuroanatomy | larval stage phenotype of N^{UAS.Tag:V5,Tag:polyHis}, Scer\GAL4^insc-Mz1407, mir-ban^{sponge.UAS.DsRed(Unk)}

(Wu et al., 2017)

CycE^UAS.cLa, Scer\GAL4^insc-Mz1407 is a non-enhancer of increased cell number | larval stage phenotype of N^{UAS.Tag:V5,Tag:polyHis}, Scer\GAL4^insc-Mz1407, mir-ban^{sponge.UAS.DsRed(Unk)}

(Wu et al., 2017)

Suppressor of

Statement

Reference

CycE^UAS.cLa, Scer\GAL4^wor.PA, Scer\GAL80^ase.PN is a suppressor | partially of abnormal cell number | larval stage phenotype of γCOP^HM05099, Scer\GAL4^wor.PA, Scer\GAL80^ase.PN

(Zhang et al., 2024)

CycE^UAS.cLa, Scer\GAL80^ase.PN, Scer\GAL4^wor.PA is a suppressor | partially of abnormal cell number | larval stage phenotype of Scer\GAL4^wor.PA, Scer\GAL80^ase.PN, Syx18^JF02263

(Zhang et al., 2024)

CycE^UAS.cLa, Scer\GAL4^wor.PA, Scer\GAL80^ase.PN is a suppressor | partially of abnormal cell number | larval stage phenotype of KdelR^HMC05779, Scer\GAL4^wor.PA, Scer\GAL80^ase.PN

(Zhang et al., 2024)

CycE^UAS.cLa, Scer\GAL4^ey.PU is a suppressor of decreased size | adult stage phenotype of Ciao1^GD7831, Scer\GAL4^ey.PU

(Jung et al., 2020)

CycE^UAS.cLa, Scer\GAL4^ey.PU is a suppressor of decreased size | adult stage phenotype of Scer\GAL4^ey.PU, Xpd^KK101234

(Jung et al., 2020)

Scer\GAL4^elav-C155/CycE^UAS.cLa is a suppressor of decreased occurrence of cell division | embryonic stage 14 phenotype of wor⁴/Df(2L)ED1054

(Bahrampour et al., 2017)

CycE^UAS.cLa, Scer\GAL4^salm.EPv is a suppressor of visible phenotype of Scer\GAL4^salm.EPv, caup^UAS.Tag:HA

(Barrios et al., 2015)

CycE^UAS.cLa, Scer\GAL4^MD-638 is a suppressor of visible phenotype of Scer\GAL4^MD-638, ara^UAS.cGa

(Barrios et al., 2015)

CycE^UAS.cLa, Scer\GAL4^nub.PU is a suppressor of decreased occurrence of cell division | larval stage phenotype of Scer\GAL4^nub.PU, caup^UAS.Tag:HA

(Barrios et al., 2015)

CycE^UAS.cLa, Scer\GAL4^ap-md544 is a suppressor of decreased occurrence of cell division | larval stage phenotype of Scer\GAL4^ap-md544, caup^UAS.Tag:HA

(Barrios et al., 2015)

CycE^UAS.cLa, Scer\GAL4^nub.PU is a suppressor of decreased occurrence of cell division | larval stage phenotype of Scer\GAL4^nub.PU, ara^UAS.cGa

(Barrios et al., 2015)

CycE^UAS.cLa, Scer\GAL4^nub.PU is a suppressor of decreased occurrence of cell division | larval stage phenotype of Scer\GAL4^nub.PU, mirr^UAS.cMa

(Barrios et al., 2015)

CycE^UAS.cLa, Scer\GAL4^en-e16E is a suppressor | partially of visible | adult stage phenotype of Scer\GAL4^en-e16E, Skp2^KK108837

(Dui et al., 2013)

CycE^UAS.cLa, Scer\GAL4^GMR.PU is a suppressor | partially of visible phenotype of E2f1^RNAi.UAS.cJa, Scer\GAL4^GMR.PU

(Ji et al., 2012)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor | partially of visible phenotype of Scer\GAL4^ey.PH, kibra^UAS.cBa

(Baumgartner et al., 2010)

Diap1^EP3723/CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of visible phenotype of Scer\GAL4^ey.PH, kibra^UAS.cBa

(Baumgartner et al., 2010)

CycE^UAS.cLa, Scer\GAL4^en-e16E is a suppressor of abnormal size phenotype of Dcr-1^GD11429, Scer\GAL4^en-e16E

(Herranz et al., 2010)

CycE^UAS.cLa, Scer\GAL4^en-e16E is a suppressor of decreased cell growth rate phenotype of Dcr-1^GD11429, Scer\GAL4^en-e16E

(Herranz et al., 2010)

CycE^UAS.cLa, Scer\GAL4^en-e16E is a suppressor of visible phenotype of Hsap\TGIF2LX^UAS.Tag:MYC, Scer\GAL4^en-e16E

(Wang et al., 2008)

CycE^UAS.cLa, Scer\GAL4^en-e16E is a suppressor of abnormal size phenotype of Hsap\TGIF2LX^UAS.Tag:MYC, Scer\GAL4^en-e16E

(Wang et al., 2008)

CycE^UAS.cLa, Scer\GAL4^en-e16E is a suppressor of decreased cell size | adult stage phenotype of Hsap\TGIF2LX^UAS.Tag:MYC, Scer\GAL4^en-e16E

(Wang et al., 2008)

CycE^UAS.cLa, Scer\GAL4^en-e16E is a suppressor of decreased cell number | adult stage phenotype of Hsap\TGIF2LX^UAS.Tag:MYC, Scer\GAL4^en-e16E

(Wang et al., 2008)

CycE^UAS.cLa, Scer\GAL4^prd.RG1 is a suppressor of abnormal mitotic cell cycle | embryonic stage phenotype of Scer\GAL4^prd.RG1, fzr^psm.UAS

(Reber et al., 2006)

Scer\GAL4^prd.RG1/CycE^UAS.cLa is a suppressor of abnormal mitotic cell cycle | embryonic stage phenotype of CycA^C8LR1

(Reber et al., 2006)

CycE^UAS.cLa, Scer\GAL4^ey.PB is a suppressor of abnormal size | larval stage phenotype of N^DN.UAS.cUa, Scer\GAL4^ey.PB

(Kenyon et al., 2003)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of abnormal size | larval stage phenotype of N^DN.UAS.cUa, Scer\GAL4^ey.PH

(Kenyon et al., 2003)

CycE^UAS.cLa, Scer\GAL4^ey.PB is a suppressor of decreased occurrence of cell division | larval stage phenotype of N^DN.UAS.cUa, Scer\GAL4^ey.PB

(Kenyon et al., 2003)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of decreased occurrence of cell division | larval stage phenotype of N^DN.UAS.cUa, Scer\GAL4^ey.PH

(Kenyon et al., 2003)

Scer\GAL4^prd.RG1/CycE^UAS.cLa is a suppressor of abnormal mitotic cell cycle phenotype of Rca1²

(Grosskortenhaus and Sprenger, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of visible phenotype of NFAT^EP1335, Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of visible phenotype of Pka-R2^EP2162, Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of visible phenotype of Scer\GAL4^ey.PH, fng^EP3082

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of visible phenotype of CG6701^EP2054, Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of visible phenotype of NFAT^EP1390, Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of visible phenotype of CG9932^EP2317, Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of visible phenotype of Incenp^EP2340, Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of lethal phenotype of CG42709^EP3622, Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of visible phenotype of Scer\GAL4^ey.PH, kibra^EP666

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of visible phenotype of Scer\GAL4^ey.PH, elB^EP2039

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of visible phenotype of Scer\GAL4^ey.PH, shn^EP2359

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of visible phenotype of Scer\GAL4^ey.PH, Traf4^EP578

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of visible phenotype of EP3617^EP3617, Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of visible phenotype of Scer\GAL4^ey.PH, pbl^EP3415

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of visible phenotype of Scer\GAL4^ey.PH, pygo^EP1076

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of visible phenotype of CG12084^EP3673, Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of visible phenotype of Rac2^EP3118, Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of visible phenotype of Scer\GAL4^ey.PH, elB^EP965

(Tseng and Hariharan, 2002)

Scer\GAL4^mf9/CycE^UAS.cLa is a suppressor of male sterile phenotype of Df(2L)Prl/prd⁴, prd^mf9

(Xue and Noll, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of visible phenotype of Scer\GAL4^ey.PH, prd^UAS.cJa

(Jiao et al., 2001)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor | partially of visible phenotype of Poxn^UAS.cJa, Scer\GAL4^ey.PH

(Jiao et al., 2001)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor | partially of visible phenotype of Scer\GAL4^ey.PH, sim^UAS.cXa

(Jiao et al., 2001)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor | partially of lethal | pharate adult stage phenotype of Antp^UAS.cMb, Scer\GAL4^ey.PH

(Jiao et al., 2001)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor | partially of visible phenotype of Antp^UAS.cMb, Scer\GAL4^ey.PH

(Jiao et al., 2001)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of visible phenotype of Scer\GAL4^ey.PH, gsb^UAS.cJa

(Jiao et al., 2001)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor | partially of visible phenotype of Scer\GAL4^ey.PH, sv^UAS.cKa

(Jiao et al., 2001)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of visible phenotype of Poxm^UAS.cJa, Scer\GAL4^ey.PH

(Jiao et al., 2001)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor | partially of visible phenotype of Scer\GAL4^ey.PH, dac^UAS.cSa

(Jiao et al., 2001)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor | partially of visible phenotype of Mef2^UAS.cBa, Scer\GAL4^ey.PH

(Jiao et al., 2001)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of abnormal size | adult stage phenotype of Scer\GAL4^ey.PH, Tsc1^UAS.cTa, gig^UAS.cTa

(Tapon et al., 2001)

CycE^UAS.cLa, Scer\GAL4^en-e16E is a suppressor of increased cell death phenotype of Scer\GAL4^en-e16E, tum^ΔE1E.UAS

(Sotillos and Campuzano, 2000)

CycE^UAS.cLa, Scer\GAL4^en-e16E is a suppressor of abnormal mitotic cell cycle phenotype of Scer\GAL4^en-e16E, tum^ΔE1E.UAS

(Sotillos and Campuzano, 2000)

CycE^UAS.cLa, Scer\GAL4^en-e16E is a suppressor | partially of increased cell death phenotype of Hsap\CDKN1A^UAS.cHa, Scer\GAL4^en-e16E

(Sotillos and Campuzano, 2000)

CycE^UAS.cLa, Scer\GAL4^en-e16E is a suppressor | partially of abnormal planar polarity phenotype of Hsap\CDKN1A^UAS.cHa, Scer\GAL4^en-e16E

(Sotillos and Campuzano, 2000)

CycE^UAS.cLa, Scer\GAL4^en-e16E is a suppressor | partially of visible phenotype of Hsap\CDKN1A^UAS.cHa, Scer\GAL4^en-e16E

(Sotillos and Campuzano, 2000)

NOT Suppressor of

Statement

Reference

CycE^UAS.cLa, Scer\GAL4^wor.PA, Scer\GAL80^ase.PN is a non-suppressor of decreased cell number | larval stage phenotype of N^HMS00001, Scer\GAL4^wor.PA, Scer\GAL80^ase.PN

(Zhang et al., 2024)

CycE^UAS.cLa, Scer\GAL4^en.PU is a non-suppressor of visible | adult stage phenotype of Patronin^GD11946, Scer\GAL4^en.PU

(Yang and Choi, 2021)

CycE^UAS.cLa, Scer\GAL4^en.PU is a non-suppressor of decreased size | adult stage phenotype of Patronin^GD11946, Scer\GAL4^en.PU

(Yang and Choi, 2021)

CycE^UAS.cLa, Scer\GAL4^insc-Mz1407 is a non-suppressor of abnormal neuroanatomy | larval stage phenotype of Scer\GAL4^insc-Mz1407, mir-ban^{sponge.UAS.DsRed(Unk)}

(Wu et al., 2017)

CycE^UAS.cLa, Scer\GAL4^insc-Mz1407 is a non-suppressor of abnormal neuroanatomy | larval stage phenotype of N^{UAS.Tag:V5,Tag:polyHis}, Scer\GAL4^insc-Mz1407, mir-ban^{sponge.UAS.DsRed(Unk)}

(Wu et al., 2017)

CycE^UAS.cLa, Scer\GAL4^insc-Mz1407 is a non-suppressor of increased cell number | larval stage phenotype of N^{UAS.Tag:V5,Tag:polyHis}, Scer\GAL4^insc-Mz1407, mir-ban^{sponge.UAS.DsRed(Unk)}

(Wu et al., 2017)

Scer\GAL4^ey.PH/CycE^UAS.cLa is a non-suppressor of abnormal size phenotype of L^fee

(Wang and Huang, 2009)

Scer\GAL4^en-e16E/CycE^UAS.cLa is a non-suppressor of abnormal size phenotype of Egfr::tor^act.UAS

(Parker, 2006)

CycE^UAS.cLa, Scer\GAL4^Bx-MS1096 is a non-suppressor of visible phenotype of Scer\GAL4^Bx-MS1096, vri^2.UAS

(Szuplewski et al., 2003)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a non-suppressor of visible phenotype of Scer\GAL4^ey.PH, mask^EP601

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a non-suppressor of visible phenotype of NFAT^EP1508, Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a non-suppressor of visible phenotype of Scer\GAL4^ey.PH, ckd^EP3560

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a non-suppressor of lethal phenotype of Scer\GAL4^ey.PH, aop^EP2500

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a non-suppressor of visible phenotype of Scer\GAL4^ey.PH, l(3)L0539^EP3083

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a non-suppressor of visible phenotype of Scer\GAL4^ey.PH, l(3)L0539^EP3523

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a non-suppressor of visible phenotype of Scer\GAL4^ey.PH, kibra^EP747

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a non-suppressor of visible phenotype of Scer\GAL4^ey.PH, nej^EP1179

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a non-suppressor of visible phenotype of Scer\GAL4^ey.PH, ckd^EP3041

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a non-suppressor of visible phenotype of Scer\GAL4^ey.PH, hh^EP3521

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a non-suppressor of visible phenotype of Cph^EP1617, Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a non-suppressor of visible phenotype of Scer\GAL4^ey.PH, nej^EP1149

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a non-suppressor of visible phenotype of Kr-h1^EP2289, Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a non-suppressor of visible phenotype of Scer\GAL4^ey.PH, ckd^EP3689

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a non-suppressor of visible phenotype of Hr39^EP2490, Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a non-suppressor of visible phenotype of Hr4^EP1232, Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a non-suppressor of visible phenotype of Scer\GAL4^ey.PH, esg^EP684

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a non-suppressor of visible phenotype of Scer\GAL4^ey.PH, dpp^EP2232

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a non-suppressor of visible phenotype of Scer\GAL4^ey.PH, esg^EP2009

(Tseng and Hariharan, 2002)

Scer\GAL4^prd.3.1/CycE^UAS.cLa is a non-suppressor of male sterile phenotype of Df(2L)Prl/prd⁴

(Xue and Noll, 2002)

Other

Statement

Reference

CycE^UAS.cLa, Scer\GAL4^{Delta-05151-G}, stg^UAS.cNa has increased occurrence of cell division | adult stage phenotype

(Kohlmaier et al., 2015)

CycE^UAS.cLa, Scer\GAL4^Su(H).GBE, stg^UAS.cNa has increased occurrence of cell division | adult stage phenotype

(Kohlmaier et al., 2015)

Cdk2^UAS.Tag:MYC, CycE^UAS.cLa, Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^{Delta-05151-G} has increased occurrence of cell division | adult stage phenotype

(Kohlmaier et al., 2015)

Cdk2^UAS.Tag:MYC, CycE^UAS.cLa, Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^Su(H).GBE has increased occurrence of cell division | adult stage phenotype

(Kohlmaier et al., 2015)

CycA^UAS.cWa, CycE^UAS.cLa, Scer\GAL4^GMR.PF has increased occurrence of cell division | larval stage phenotype

(Baonza and Freeman, 2005)

CycE^UAS.cLa, Scer\GAL4^bi-omb-Gal4, eya^unspecified has increased occurrence of cell division | larval stage phenotype

(Rangarajan et al., 2001)

CycE^UAS.cLa, Scer\GAL4^prd.RG1, fzr^UAS.cSa has increased occurrence of cell division | embryonic cycle 16 phenotype

(Sigrist and Lehner, 1997)

Phenotype Manifest In

Enhanced by

Statement

Reference

CycE^UAS.cLa has embryonic segment posterior compartment phenotype, enhanceable by Scer\GAL4^en-e16E

(Parker, 2006)

CycE^UAS.cLa, Scer\GAL4^en-e16E has embryonic segment posterior compartment phenotype, enhanceable by Scer\GAL4^en-e16E

(Parker, 2006)

NOT Enhanced by

Statement

Reference

CycE^UAS.cLa, Scer\GAL4^GMR.PF has eye disc phenotype, non-enhanceable by Delta^UAS.cJa, Scer\GAL4^GMR.PF

(Baonza and Freeman, 2005)

Suppressed by

Statement

Reference

CycE^UAS.cLa, Scer\GAL4^en-e16E has embryonic segment posterior compartment phenotype, suppressible by Ras85D^V12.UAS, Scer\GAL4^en-e16E

(Parker, 2006)

CycE^UAS.cLa, Scer\GAL4^en-e16E has embryonic segment posterior compartment phenotype, suppressible by Egfr::tor^act.UAS, Scer\GAL4^en-e16E

(Parker, 2006)

CycE^UAS.cLa has embryonic segment posterior compartment phenotype, suppressible by Scer\GAL4^en-e16E/Df(3L)XR38

(Parker, 2006)

NOT suppressed by

Statement

Reference

CycE^UAS.cLa, Scer\GAL4^GMR.PF has eye disc phenotype, non-suppressible by Delta^UAS.cJa, Scer\GAL4^GMR.PF

(Baonza and Freeman, 2005)

Enhancer of

Statement

Reference

CycE^UAS.cLa, Scer\GAL4^GMR.PF is an enhancer of eye phenotype of Hsap\MAPT^{T231A.S235A.UAS}, Scer\GAL4^GMR.PF

(Steinhilb et al., 2007)

CycE^UAS.cLa, Scer\GAL4^GMR.PF is an enhancer of eye phenotype of Hsap\MAPT^{S396A.S404A.UAS}, Scer\GAL4^GMR.PF

(Steinhilb et al., 2007)

CycE^UAS.cLa, Scer\GAL4^GMR.PF is an enhancer of eye phenotype of Hsap\MAPT^UAS.cWa, Scer\GAL4^GMR.PF

(Steinhilb et al., 2007)

CycE^UAS.cLa, Scer\GAL4^GMR.PF is an enhancer of eye phenotype of Hsap\MAPT^{S202A.T205A.UAS}, Scer\GAL4^GMR.PF

(Steinhilb et al., 2007)

NOT Enhancer of

Statement

Reference

CycE^UAS.cLa, Scer\GAL4^insc-Mz1407 is a non-enhancer of type II neuroblast | larval stage | increased number phenotype of N^{UAS.Tag:V5,Tag:polyHis}, Scer\GAL4^insc-Mz1407, mir-ban^{sponge.UAS.DsRed(Unk)}

(Wu et al., 2017)

Suppressor of

Statement

Reference

CycE^UAS.cLa, Scer\GAL4^wor.PA, Scer\GAL80^ase.PN is a suppressor | partially of type II neuroblast | larval stage phenotype of γCOP^HM05099, Scer\GAL4^wor.PA, Scer\GAL80^ase.PN

(Zhang et al., 2024)

CycE^UAS.cLa, Scer\GAL80^ase.PN, Scer\GAL4^wor.PA is a suppressor | partially of type II neuroblast | larval stage phenotype of Scer\GAL4^wor.PA, Scer\GAL80^ase.PN, Syx18^JF02263

(Zhang et al., 2024)

CycE^UAS.cLa, Scer\GAL4^wor.PA, Scer\GAL80^ase.PN is a suppressor | partially of type II neuroblast | larval stage phenotype of KdelR^HMC05779, Scer\GAL4^wor.PA, Scer\GAL80^ase.PN

(Zhang et al., 2024)

CycE^UAS.cLa, Scer\GAL4^ey.PU is a suppressor of eye phenotype of Ciao1^GD7831, Scer\GAL4^ey.PU

(Jung et al., 2020)

CycE^UAS.cLa, Scer\GAL4^ey.PU is a suppressor of eye phenotype of Scer\GAL4^ey.PU, Xpd^KK101234

(Jung et al., 2020)

Scer\GAL4^elav-C155/CycE^UAS.cLa is a suppressor of embryonic neuroblast | embryonic stage 14 phenotype of wor⁴/Df(2L)ED1054

(Bahrampour et al., 2017)

Scer\GAL4^elav-C155/CycE^UAS.cLa is a suppressor of embryonic ganglion mother cell | embryonic stage 14 phenotype of wor⁴/Df(2L)ED1054

(Bahrampour et al., 2017)

CycE^UAS.cLa, Scer\GAL4^salm.EPv is a suppressor of wing phenotype of Scer\GAL4^salm.EPv, caup^UAS.Tag:HA

(Barrios et al., 2015)

CycE^UAS.cLa, Scer\GAL4^salm.EPv is a suppressor of wing vein phenotype of Scer\GAL4^salm.EPv, caup^UAS.Tag:HA

(Barrios et al., 2015)

CycE^UAS.cLa, Scer\GAL4^MD-638 is a suppressor of wing phenotype of Scer\GAL4^MD-638, ara^UAS.cGa

(Barrios et al., 2015)

CycE^UAS.cLa, Scer\GAL4^MD-638 is a suppressor of mesonotum | ectopic phenotype of Scer\GAL4^MD-638, ara^UAS.cGa

(Barrios et al., 2015)

CycE^UAS.cLa, Scer\GAL4^nub.PU is a suppressor of wing disc | larval stage phenotype of Scer\GAL4^nub.PU, caup^UAS.Tag:HA

(Barrios et al., 2015)

CycE^UAS.cLa, Scer\GAL4^ap-md544 is a suppressor of wing disc | larval stage phenotype of Scer\GAL4^ap-md544, caup^UAS.Tag:HA

(Barrios et al., 2015)

CycE^UAS.cLa, Scer\GAL4^nub.PU is a suppressor of wing disc | larval stage phenotype of Scer\GAL4^nub.PU, ara^UAS.cGa

(Barrios et al., 2015)

CycE^UAS.cLa, Scer\GAL4^nub.PU is a suppressor of wing disc | larval stage phenotype of Scer\GAL4^nub.PU, mirr^UAS.cMa

(Barrios et al., 2015)

CycE^UAS.cLa, Scer\GAL4^en-e16E is a suppressor | partially of wing hair phenotype of Scer\GAL4^en-e16E, Skp2^KK108837

(Dui et al., 2013)

CycE^UAS.cLa, Scer\GAL4^GMR.PU is a suppressor | partially of eye phenotype of E2f1^RNAi.UAS.cJa, Scer\GAL4^GMR.PU

(Ji et al., 2012)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor | partially of eye phenotype of Scer\GAL4^ey.PH, kibra^UAS.cBa

(Baumgartner et al., 2010)

Diap1^EP3723/CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of eye phenotype of Scer\GAL4^ey.PH, kibra^UAS.cBa

(Baumgartner et al., 2010)

CycE^UAS.cLa, Scer\GAL4^en-e16E is a suppressor of wing blade phenotype of Dcr-1^GD11429, Scer\GAL4^en-e16E

(Herranz et al., 2010)

CycE^UAS.cLa, Scer\GAL4^GMR.PF is a suppressor | partially of eye | temperature conditional phenotype of PEK^UAS.cMa, Scer\GAL4^GMR.PF

(Malzer et al., 2010)

CycE^UAS.cLa, Scer\GAL4^en-e16E is a suppressor of wing | posterior phenotype of Hsap\TGIF2LX^UAS.Tag:MYC, Scer\GAL4^en-e16E

(Wang et al., 2008)

CycE^UAS.cLa, Scer\GAL4^prd.RG1 is a suppressor of embryonic epidermis phenotype of Scer\GAL4^prd.RG1, fzr^psm.UAS

(Reber et al., 2006)

Scer\GAL4^prd.RG1/CycE^UAS.cLa is a suppressor of embryonic epidermis phenotype of CycA^C8LR1

(Reber et al., 2006)

Scer\GAL4^neur-P72/CycE^UAS.cLa is a suppressor of PNS glial cell phenotype of dap⁴

(Audibert et al., 2005)

CycE^UAS.cLa, Scer\GAL4^ey.PB is a suppressor of eye disc phenotype of N^DN.UAS.cUa, Scer\GAL4^ey.PB

(Kenyon et al., 2003)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of eye disc phenotype of N^DN.UAS.cUa, Scer\GAL4^ey.PH

(Kenyon et al., 2003)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of eye phenotype of NFAT^EP1335, Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of eye phenotype of Pka-R2^EP2162, Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of eye phenotype of Scer\GAL4^ey.PH, fng^EP3082

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of eye phenotype of CG6701^EP2054, Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of eye phenotype of NFAT^EP1390, Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of eye phenotype of CG9932^EP2317, Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of eye phenotype of Incenp^EP2340, Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of eye phenotype of Scer\GAL4^ey.PH, kibra^EP666

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of eye phenotype of Scer\GAL4^ey.PH, elB^EP2039

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of eye phenotype of Scer\GAL4^ey.PH, shn^EP2359

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of eye phenotype of Scer\GAL4^ey.PH, Traf4^EP578

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of eye phenotype of EP3617^EP3617, Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of eye phenotype of Scer\GAL4^ey.PH, pbl^EP3415

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of eye phenotype of Scer\GAL4^ey.PH, pygo^EP1076

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of eye phenotype of CG12084^EP3673, Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of eye phenotype of Rac2^EP3118, Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of eye phenotype of Scer\GAL4^ey.PH, elB^EP965

(Tseng and Hariharan, 2002)

Scer\GAL4^mf9/CycE^UAS.cLa is a suppressor of male accessory gland phenotype of Df(2L)Prl/prd⁴, prd^mf9

(Xue and Noll, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of adult head phenotype of Scer\GAL4^ey.PH, prd^UAS.cJa

(Jiao et al., 2001)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor | partially of adult head phenotype of Poxn^UAS.cJa, Scer\GAL4^ey.PH

(Jiao et al., 2001)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor | partially of adult head phenotype of Scer\GAL4^ey.PH, sim^UAS.cXa

(Jiao et al., 2001)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor | partially of adult head phenotype of Antp^UAS.cMb, Scer\GAL4^ey.PH

(Jiao et al., 2001)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of adult head phenotype of Scer\GAL4^ey.PH, gsb^UAS.cJa

(Jiao et al., 2001)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor | partially of adult head phenotype of Scer\GAL4^ey.PH, sv^UAS.cKa

(Jiao et al., 2001)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of adult head phenotype of Poxm^UAS.cJa, Scer\GAL4^ey.PH

(Jiao et al., 2001)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor | partially of adult head phenotype of Scer\GAL4^ey.PH, dac^UAS.cSa

(Jiao et al., 2001)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor | partially of adult head phenotype of Mef2^UAS.cBa, Scer\GAL4^ey.PH

(Jiao et al., 2001)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a suppressor of eye phenotype of Scer\GAL4^ey.PH, Tsc1^UAS.cTa, gig^UAS.cTa

(Tapon et al., 2001)

CycE^UAS.cLa, Scer\GAL4^en-e16E is a suppressor of wing & cell phenotype of Scer\GAL4^en-e16E, tum^ΔE1E.UAS

(Sotillos and Campuzano, 2000)

CycE^UAS.cLa, Scer\GAL4^69B is a suppressor of wing & trichome phenotype of Scer\GAL4^69B, tum^ΔE1E.UAS

(Sotillos and Campuzano, 2000)

CycE^UAS.cLa, Scer\GAL4^en-e16E is a suppressor | partially of wing & cell phenotype of Hsap\CDKN1A^UAS.cHa, Scer\GAL4^en-e16E

(Sotillos and Campuzano, 2000)

CycE^UAS.cLa, Scer\GAL4^en-e16E is a suppressor | partially of wing & trichome phenotype of Hsap\CDKN1A^UAS.cHa, Scer\GAL4^en-e16E

(Sotillos and Campuzano, 2000)

CycE^UAS.cLa, Scer\GAL4^en-e16E is a suppressor | partially of wing phenotype of Hsap\CDKN1A^UAS.cHa, Scer\GAL4^en-e16E

(Sotillos and Campuzano, 2000)

CycE^UAS.cLa, Scer\GAL4^prd.RG1 is a suppressor of cell cycle phenotype of Scer\GAL4^prd.RG1, dap^UAS.cLa

(Lane et al., 1996)

NOT Suppressor of

Statement

Reference

CycE^UAS.cLa, Scer\GAL4^wor.PA, Scer\GAL80^ase.PN is a non-suppressor of type II neuroblast | larval stage | decreased number phenotype of N^HMS00001, Scer\GAL4^wor.PA, Scer\GAL80^ase.PN

(Zhang et al., 2024)

CycE^UAS.cLa, Scer\GAL4^en.PU is a non-suppressor of wing phenotype of Patronin^GD11946, Scer\GAL4^en.PU

(Yang and Choi, 2021)

CycE^UAS.cLa, Scer\GAL4^insc-Mz1407 is a non-suppressor of intermediate neuronal progenitor | larval stage phenotype of Scer\GAL4^insc-Mz1407, mir-ban^{sponge.UAS.DsRed(Unk)}

(Wu et al., 2017)

CycE^UAS.cLa, Scer\GAL4^insc-Mz1407 is a non-suppressor of nucleolus | larval stage phenotype of Scer\GAL4^insc-Mz1407, mir-ban^{sponge.UAS.DsRed(Unk)}

(Wu et al., 2017)

CycE^UAS.cLa, Scer\GAL4^insc-Mz1407 is a non-suppressor of type II neuroblast | increased number | larval stage phenotype of N^{UAS.Tag:V5,Tag:polyHis}, Scer\GAL4^insc-Mz1407, mir-ban^{sponge.UAS.DsRed(Unk)}

(Wu et al., 2017)

Scer\GAL4^ey.PH/CycE^UAS.cLa is a non-suppressor of eye phenotype of L^fee

(Wang and Huang, 2009)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a non-suppressor of eye phenotype of Scer\GAL4^ey.PH, mask^EP601

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a non-suppressor of eye phenotype of NFAT^EP1508, Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a non-suppressor of eye phenotype of Scer\GAL4^ey.PH, ckd^EP3560

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a non-suppressor of eye phenotype of Scer\GAL4^ey.PH, l(3)L0539^EP3083

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a non-suppressor of eye phenotype of Scer\GAL4^ey.PH, kibra^EP747

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a non-suppressor of eye phenotype of Scer\GAL4^ey.PH, nej^EP1179

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a non-suppressor of eye phenotype of Scer\GAL4^ey.PH, ckd^EP3041

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a non-suppressor of eye phenotype of Scer\GAL4^ey.PH, hh^EP3521

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a non-suppressor of eye phenotype of Scer\GAL4^ey.PH, l(3)L0539^EP3523

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a non-suppressor of eye phenotype of Cph^EP1617, Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a non-suppressor of eye phenotype of Scer\GAL4^ey.PH, nej^EP1149

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a non-suppressor of eye phenotype of Kr-h1^EP2289, Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a non-suppressor of eye phenotype of Scer\GAL4^ey.PH, ckd^EP3689

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a non-suppressor of eye phenotype of Hr39^EP2490, Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a non-suppressor of eye phenotype of Hr4^EP1232, Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a non-suppressor of eye phenotype of Scer\GAL4^ey.PH, esg^EP684

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a non-suppressor of eye phenotype of Scer\GAL4^ey.PH, dpp^EP2232

(Tseng and Hariharan, 2002)

CycE^UAS.cLa, Scer\GAL4^ey.PH is a non-suppressor of eye phenotype of Scer\GAL4^ey.PH, esg^EP2009

(Tseng and Hariharan, 2002)

Scer\GAL4^prd.3.1/CycE^UAS.cLa is a non-suppressor of male accessory gland phenotype of Df(2L)Prl/prd⁴

(Xue and Noll, 2002)

CycE^UAS.cLa, Scer\GAL4^en-e16E is a non-suppressor of wing vein phenotype of Scer\GAL4^en-e16E, tum^ΔE1E.UAS

(Sotillos and Campuzano, 2000)

Other

Statement

Reference

CycE^UAS.cLa, Scer\GAL4^salm.EPv, caup^UAS.Tag:HA, yki^UAS.cUa has eye phenotype

(Barrios et al., 2015)

CycE^UAS.cLa, Scer\GAL4^{Delta-05151-G}, stg^UAS.cNa has adult midgut phenotype

(Kohlmaier et al., 2015)

CycE^UAS.cLa, Scer\GAL4^Su(H).GBE, stg^UAS.cNa has adult midgut phenotype

(Kohlmaier et al., 2015)

Cdk2^UAS.Tag:MYC, CycE^UAS.cLa, Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^{Delta-05151-G} has adult midgut phenotype

(Kohlmaier et al., 2015)

Cdk2^UAS.Tag:MYC, CycE^UAS.cLa, Dp^UAS.cDa, E2f1^UAS.cNa, Scer\GAL4^Su(H).GBE has adult midgut phenotype

(Kohlmaier et al., 2015)

CycE^UAS.cLa, Scer\GAL4^sd-SG29.1, stg^UAS.cNa has dorsal-ventral compartment boundary of the wing disc | third instar larval stage phenotype

(Becam et al., 2011)

BacA\p35^UAS.cHa, CycE^UAS.cLa, Scer\GAL4^en-e16E has embryonic segment posterior compartment phenotype

(Parker, 2006)

Cdk2^UAS.Tag:MYC, CycE^UAS.cLa, Scer\GAL4^GMR.PF has eye disc & photoreceptor cell phenotype

(Chen et al., 2003)

CycE^UAS.cLa, Scer\GAL4^bi-omb-Gal4, eya^unspecified has larval glial cell | larval stage phenotype

(Rangarajan et al., 2001)

CycE^UAS.cLa, Scer\GAL4^bi-omb-Gal4, eya^unspecified has embryonic/larval optic stalk | larval stage phenotype

(Rangarajan et al., 2001)

Additional Comments

Genetic Interactions

Statement

Reference

The expression of CycE^Scer\UAS.cLa under the control of Scer\GAL4^elav-C155 suppresses the decreased neuroblast/neuroblast daughter divisions observed in wor⁴/Df(2L)ED1054 transheterozygous stage 14 embryos.

(Bahrampour et al., 2017)

Co-expression of CycE^Scer\UAS.cLa fails to suppress the decreased nucleolar size phenotype seen in secondary neuroblasts in larval brains expressing ban^{sponge.Scer\UAS.T:Disc\RFP} under the control of Scer\GAL4^insc-Mz1407.

The co-expression of CycE^Scer\UAS.cLa does not change the number of neuroblasts per brain lobe seen in larval brains expressing both ban^{sponge.Scer\UAS.T:Disc\RFP} and N^{Scer\UAS.T:SV5\V5,T:Zzzz\His6} under the control of Scer\GAL4^insc-Mz1407.

(Wu et al., 2017)

Expression of CycE^Scer\UAS.cLa suppresses the cell proliferation defects seen in the wing disc when caup^{Scer\UAS.T:Ivir\HA1} is expressed under the control of either Scer\GAL4^nub.PU or Scer\GAL4^ap-md544 (restricted to 16 hours prior the third instar larval stage onwards using Scer\GAL80^ts.αTub84B).

Expression of CycE^Scer\UAS.cLa suppresses the cell proliferation defects seen in the wing disc when mirr^Scer\UAS.cMa is expressed under the control of Scer\GAL4^nub.PU (restricted to 16 hours prior the third instar larval stage onwards using Scer\GAL80^ts.αTub84B).

Expression of CycE^Scer\UAS.cLa suppresses the cell proliferation defects seen in the wing disc when ara^Scer\UAS.cGa is expressed under the control of Scer\GAL4^nub.PU (restricted to 16 hours prior the third instar larval stage onwards using Scer\GAL80^ts.αTub84B).

Expression of caup^{Scer\UAS.T:Ivir\HA1} suppresses the eye disc overgrowth seen when yki^Scer\UAS.cUa is expressed under the control of Scer\GAL4^salm.EPv. This suppression is partially reverted upon co-expression of CycE^Scer\UAS.cLa.

Expression of CycE^Scer\UAS.cLa suppresses the wing phenotypes seen when caup^{Scer\UAS.T:Ivir\HA1} is expressed under the control of Scer\GAL4^salm.EPv.

Expression of CycE^Scer\UAS.cLa suppresses the wing loss and formation of ectopic notum tissue seen when ara^Scer\UAS.cGa is expressed in the prospective wing pouch under the control of Scer\GAL4^MD-638.

(Barrios et al., 2015)

Co-expression of CycE^Scer\UAS.cLa almost completely suppresses the wing hair spacing phenotype seen when Skp2^KK108837 is expressed under the control of Scer\GAL4^en-e16E.

(Dui et al., 2013)

The strong rough eye phenotype seen in flies expressing multiple copies of E2f^{dsRNA.Scer\UAS.cJa} under the control of Scer\GAL4^GMR.PU is partially suppressed by co-expression of CycE^Scer\UAS.cLa.

(Ji et al., 2012)

Late third instar wing discs expressing CycE^Scer\UAS.cLa and stg^Scer\UAS.cNa under the control of Scer\GAL4^sd-SG29.1 have disturbed dorsal-ventral (DV) boundaries compared to controls.

(Becam et al., 2011)

The small eye phenotype caused by expression of kibra^Scer\UAS.cBa under the control of Scer\GAL4^ey.PH is partially rescued by co-expression of either th^EP3723 or CycE^Scer\UAS.cLa. Simultaneous co-expression of both th^EP3723 and CycE^Scer\UAS.cLa almost completely rescues the small eye phenotype caused by expression of kibra^Scer\UAS.cBa under the control of Scer\GAL4^ey.PH.

(Baumgartner et al., 2010)

Expression of stg^Scer\UAS.cNa and CycE^Scer\UAS.cLa (using the MARCM system under the control of Scer\GAL4^tub.PU) fails to rescue the growth defects seen in Df(1)btd-Sp1 leg disc clones generated in second instar larvae.

(Estella and Mann, 2010)

Co-expression of CycE^Scer\UAS.cLa with Scer\GAL4^en-e16E>Dcr-1^GD11429 restores cell and wing size.

(Herranz et al., 2010)

The small, depigmented-eye phenotype of flies expressing PEK^Scer\UAS.cMa under the control of Scer\GAL4^GMR.PF is partially suppressed by co-expression of CycE^Scer\UAS.cLa.

(Malzer et al., 2010)

Expression of CycE^Scer\UAS.cLa under the control of Scer\GAL4^ey.PH in a L^fee mutant background does not restore eye size.

(Wang and Huang, 2009)

Co-expression of geminin^{dsRNA.Scer\UAS} with CycE^Scer\UAS.cLa in 'flip out' clones in salivary glands does not rescue the block to DNA replication associated with the expression of CycE^Scer\UAS.cLa alone.

(Narbonne-Reveau et al., 2008)

Expressing CycE^Scer\UAS.cLa under the control of Scer\GAL4^en-e16E in Df(3L)XR38 embryos reduces the level of apoptosis in embryonic posterior compartment cells by 59% compared to when CycE^Scer\UAS.cLa is expressed in a wild-type background. Likewise, Scer\GAL4^en-e16E>CycE^Scer\UAS.cLa expression in a W⁰⁵⁰¹⁴ background reduces apoptosis in these cells by 65%.

Coexpression of Egfr::tor^act.Scer\UAS and CycE^Scer\UAS.cLa, under the control of Scer\GAL4^en-e16E, blocks CycE^Scer\UAS.cLa-induced apoptosis in the embryonic posterior compartment cells. There is a reduction in compartment size, similar to that seen when only Egfr::tor^act.Scer\UAS is expressed, and cells are of a size similar to that seen when only CycE^Scer\UAS.cLa is expressed. The same phenotype occurs when Ras85D^V12.Scer\UAS and CycE^Scer\UAS.cLa are coexpressed.

Embryos that coexpress Egfr^DN.Scer\UAS and CycE^Scer\UAS.cLa, under the control of Scer\GAL4^en-e16E, show approximately double the amount of apoptosis in cells of posterior compartments relative to expressing CycE^Scer\UAS.cLa alone.

Expression of CycE^Scer\UAS.cLa, under the control of Scer\GAL4^en-e16E, in spi¹ embryos increases cell death in the posterior compartment, relative to expression of CycE^Scer\UAS.cLa in a wild-type background.

(Parker, 2006)

Expression of CycE^Scer\UAS.cLa under the control of Scer\GAL4^prd.RG1 suppresses the mitotic phenotype of CycA^C8LR1 embryos so that cells progress through mitosis 16 and a subsequent S phase.

Coexpression of either CycE^Scer\UAS.cLa with rap^psm.Scer\UAS, under the control of Scer\GAL4^prd.RG1, suppresses the inhibition of embryonic mitosis 16 seen when rap^psm.Scer\UAS is expressed alone.

(Reber et al., 2006)

Expression of CycE^Scer\UAS.cLa under the control of Scer\GAL4^neur-P72, in a dap⁴/+ background, induces an S-phase in 35% of sibling glial cells and 100% of pIIIb cells.

(Audibert et al., 2005)

Co-expression of Dl^Scer\UAS.cJa does not significantly modify the excess mitoses phenotype caused by Scer\GAL4^GMR.PF-driven expression of CycE^Scer\UAS.cLa.

(Baonza and Freeman, 2005)

dm^Scer\UAS.cZa does not rescue salivary gland size in CycE^Scer\UAS.cLa; Scer\GAL4^ptc-559.1 larvae, but does rescue endoreplication in this tissue to a limited degree.

(Pierce et al., 2004)

Co-expression of Cdk2^{Scer\UAS.T:Hsap\MYC} with CycE^Scer\UAS.cLa driven by Scer\GAL4^GMR.PF blocks some photoreceptor differentiation in the third instar eye disc. The phenotype of these discs is largely unaffected by upd1^Scer\UAS.cCa.

(Chen et al., 2003)

When CycE^Scer\UAS.cLa is expressed under the control of either Scer\GAL4^ey.PB or Scer\GAL4^ey.PH in N^DN.Scer\UAS eye discs, rescue of the N^DN.Scer\UAS mitotic phenotype is seen; eye discs are larger and contain more proliferating cells.

(Kenyon et al., 2003)

Coexpression of dlt^{dsRNA.Scer\UAS} and CycE^Scer\UAS.cLa, both under the control of Scer\GAL4^ptc-559.1, results in a dramatic loss of wing cells.

(Pielage et al., 2003)

CycE^Scer\UAS.cLa; Scer\GAL4^prd.RG1 suppresses the mitotic block due to Rca1²/Rca1³, in alternate segments.

(Grosskortenhaus and Sprenger, 2002)

When CycE^Scer\UAS.cLa (driven by Scer\GAL4^mf9) is added to Df(2L)Prl/prd⁴, (partially rescued by a weakly expressing prd^mf9 line), the accessory gland phenotype is reduced, and male fertility is restored. When CycE^Scer\UAS.cLa (driven by Scer\GAL4^prd.3.1) is added to Df(2L)Prl/prd⁴, however, no rescue is seen.

(Xue and Noll, 2002)

When CycE^Scer\UAS.cLa is driven by Scer\GAL4^bi-omb-Gal4, in a eya^unspecified background, glial cells in the optic stalk undergo excessive proliferation. However these glial cells never enter the eye disc.

(Rangarajan et al., 2001)

Expression of both Tsc1^Scer\UAS.cTa and gig^Scer\UAS.cTa in the eye under the control of Scer\GAL4^ey.PH results in a much smaller eye than normal. Coexpression of CycE^Scer\UAS.cLa fully suppresses the phenotype.

(Tapon et al., 2001)

stg^Scer\UAS.cNa and CycE^Scer\UAS.cLa bypass the effects of Rbf^Scer\UAS.cDa on cell cycle phasing, cell numbers and cell size when they are both co-expressed with Rbf^Scer\UAS.cDa using Scer\GAL4^en-e16E.

(Neufeld et al., 1998)

Embryos expressing CycE^Scer\UAS.cLa or both CycE^Scer\UAS.cLa and rap^Scer\UAS.cSa under the control of Scer\GAL4^prd.RG1 show normal development until and including mitosis 16 followed by an extra division cycle.

(Sigrist and Lehner, 1997)

Xenogenetic Interactions

Statement

Reference

Expression of CycE^Scer\UAS.cLa partially suppresses the growth phenotype seen in the wings of flies expressing Hsap\TGIF2LX^{Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^en-e16E.

(Wang et al., 2008)

Co-expression of dap^{Scer\UAS.cdNa} and Rbf^Scer\UAS.cDa substantially suppresses the Scer\GAL4^GMR.PF>Hsap\MAPT^{S396A.S404A.Scer\UAS}-induced eye phenotype.

Co-expression of CycE^Scer\UAS.cLa strongly enhances the toxicity of Scer\GAL4^GMR.PF>Hsap\MAPT^{T231A.S235A.Scer\UAS}.

Co-expression of CycE^Scer\UAS.cLa strongly enhances the toxicity of Scer\GAL4^GMR.PF>Hsap\MAPT^{S202A.T205A.Scer\UAS}.

Co-expression of CycE^Scer\UAS.cLa strongly enhances the toxicity of Scer\GAL4^GMR.PF>Hsap\MAPT^Scer\UAS.cWa.

(Steinhilb et al., 2007)

Coexpression of CycE^Scer\UAS.cLa and BacA\p35^Scer\UAS.cHa, under the control of Scer\GAL4^en-e16E, in the posterior compartment cells of embryos, blocks the apoptosis of these cells that occurs when CycE^Scer\UAS.cLa is expressed alone. The posterior compartments of these embryos show a further increase in the number of cells per posterior compartment compared to those expressing only CycE^Scer\UAS.cLa (77 vs 59). The Scer\GAL4^en-e16E>CycE^Scer\UAS.cLa, BacA\p35^Scer\UAS.cHa posterior compartments do not overgrow due to an extreme reduction in average cell size.

(Parker, 2006)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

4781

w^*; P{UAS-CycE.L}ML1

Kyoto

107876

y¹ w^*; P{UAS-CycE.L}ML1

Notes on Origin

Discoverer

Comments

Overexpression of CycE^Scer\UAS.cLa using Scer\GAL4^c323 or Scer\GAL4^hs.PB does not result in incorporation of BrdU into chorion foci in stage 10A egg chambers, but does result in robust late replication of heterochromatin in stage 10A follicle cells as evidenced by increased BrdU labelling corresponding to the chromocenter.

(Calvi et al., 1998)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

CycE^Scer\UAS.cLa

CycE^UAS.cLa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Lane

(Lane et al., 1996)

Secondary FlyBase IDs

References (72)

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