FlyBase Allele Report: Dmel\nej[P]

General Information

Symbol

Dmel\nej^P

Species

D. melanogaster

Name

FlyBase ID

FBal0059991

Feature type

allele

Associated gene

Dmel\nej

Associated Insertion(s)

P{lacW}nej^P

Carried in Construct

Genomic Maps

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Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Taylor et al., 2003, Kiger et al., 2001, Akimaru et al., 1997)

Mutations Mapped to the Genome

Type

Location

Additional Notes

References

transposable element insertion site

X:9,682,686..9,682,686 [-]

(Taylor et al., 2003, Kiger et al., 2001, Akimaru et al., 1997)

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Progenitor genotype

Cytology

Nature of the lesion

Statement

Reference

Insertion of a P{lacW} element 347bp upstream of the second exon of nej.

(Akimaru et al., 1997)

Insertion components

P{lacW}nej^P

Product class / Tool use(s)

Encoded product / tool

Tagged with

nuclear protein localization tag

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

exacerbates neurodegenerative disease

modeled by Zzzz\CAG^{127Q.UAS.Tag:HA}

(Taylor et al., 2003)

ameliorates autosomal dominant cerebellar ataxia

modeled by Hsap\ATXN3^{tr.Q78.UAS.Tag:HA}

(Jung and Bonini, 2007)

modeled by Hsap\ATXN3^tr.Q46.UAS

(Jung and Bonini, 2007)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Phenotypic Data

Phenotypic Class

lethal (with nej³)

(Kumar et al., 2004)

lethal (with nej^Q7)

(Kumar et al., 2004)

lethal (with nej^S103)

(Kumar et al., 2004)

lethal (with nej^S342)

(Kumar et al., 2004)

lethal (with nej^TA57)

(Kumar et al., 2004)

visible (with nej¹³¹)

(Kumar et al., 2004)

visible (with nej^TC41)

(Kumar et al., 2004)

Phenotype Manifest In

eye (with nej¹³¹)

(Kumar et al., 2004)

eye (with nej^TC41)

(Kumar et al., 2004)

eye photoreceptor cell (with nej¹³¹)

(Kumar et al., 2004)

ommatidium (with nej¹³¹)

(Kumar et al., 2004)

ommatidium (with nej^TC41)

(Kumar et al., 2004)

Detailed Description

Statement

Reference

The nej^P/nej^TC41 and nej^P/nej¹³¹ combinations give viable adults with moderately rough eyes. The ommatidia have variable numbers of photoreceptor cells in nej^P/nej¹³¹ adults.

(Kumar et al., 2004)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhancer of

Statement

Reference

nej^P is an enhancer of eye phenotype of Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF, Zzzz\CAG^{127Q.UAS.Tag:HA}

(Taylor et al., 2003)

NOT Enhancer of

Statement

Reference

nej^P, Scer\GAL4^30A is a non-enhancer of wing phenotype of Pka-C1^UAS.cKa, Scer\GAL4^30A

(Kiger et al., 2001)

NOT Suppressor of

Statement

Reference

nej^P, Scer\GAL4^30A is a non-suppressor of wing phenotype of Pka-C1^UAS.cKa, Scer\GAL4^30A

(Kiger et al., 2001)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

3728

w^* P{lacW}nej^P/FM7c

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

P3728

(Taylor et al., 2003)

dCBP^P

(Jung and Bonini, 2007)

nej^P

nej^p

(Nagraj et al., 2007)

Name Synonyms

Secondary FlyBase IDs

References (7)

Report Sections

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