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General Information
Symbol
Dmel\wbk05612
Species
D. melanogaster
Name
FlyBase ID
FBal0060823
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Insertion components
P{lacW}wbk05612
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Homozygous embryos become abnormal during gastrulation; the germband twists and extends laterally rather than extending dorsally as in wild-type embryos. Near the completion of germband extension, the embryos show a distinct separation between the mesodermal and ectodermal tissue layers. The cuticle often has a dorsal hole. There are often fewer pericardial cells than in wild-type embryos, resulting in distinct gaps in the heart tube. The pericardial cells appear to dissociate randomly and the heart tube often appears to curve off towards the lateral side of the embryo. Significant gaps are seen in the dorsal trunk of the trachea. Somatic myotubes are often not attached to target epidermal attachment sites. This defect is most commonly seen in the ventral oblique muscles located in the anterior most segments of the embryo. Random disorganisation of myotubes and areas without myotubes are also occasionally seen. The number of photoreceptor cells is not altered in homozygous clones in the eye, but they appear disorganised.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
l(2)k05612
wbk05612
Name Synonyms
Secondary FlyBase IDs
    References (7)