Allele Dmel\htl⁸⁰

General Information
Symbol	Dmel\htl⁸⁰	Species	D. melanogaster
Name		FlyBase ID	FBal0061364
Feature type	allele	Associated gene	Dmel\htl

Allele class
Mutagen
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Cytology
Phenotypic Data
Phenotypic Class
	lethal \| recessive (Shishido et al., 1997)
Phenotype Manifest In
	abdominal 1 dorsal acute muscle 1 (Shishido et al., 1997) abdominal 2 dorsal acute muscle 1 (Shishido et al., 1997) abdominal 3 dorsal acute muscle 1 (Shishido et al., 1997) abdominal 4 dorsal acute muscle 1 (Shishido et al., 1997) abdominal 5 dorsal acute muscle 1 (Shishido et al., 1997) abdominal 6 dorsal acute muscle 1 (Shishido et al., 1997) abdominal 7 dorsal acute muscle 1 (Shishido et al., 1997) dorsal oblique muscle \| embryonic stage (Shishido et al., 1997) dorsal transverse muscle \| embryonic stage (Shishido et al., 1997) embryonic/larval dorsal vessel \| embryonic stage (Shishido et al., 1997) embryonic/larval somatic muscle (Shishido et al., 1997) embryonic myoblast (Shishido et al., 1997) embryonic visceral muscle (Shishido et al., 1997) lateral transverse muscle \| embryonic stage (Shishido et al., 1997) mesothoracic dorsal acute muscle 1 (Shishido et al., 1997) metathoracic dorsal acute muscle 1 (Shishido et al., 1997) ventral longitudinal muscle \| embryonic stage (Shishido et al., 1997) ventral oblique muscle \| embryonic stage (Shishido et al., 1997)
Detailed Description
	Statement Reference htl⁸⁰/Df(3R)sr16 and homozygous embryos lack the dorsal vessel. Dorsal oblique muscles are reduced to 26%, ventral longitudinal and oblique muscles are reduced to 54% and pleural and dorsal transverse muscles are reduced to 86% of the number present in wild-type embryos. Dorsal muscle 1 is missing. Unfused myoblasts are visible. The visceral muscles are severely defective. The cuticle appears normal. (Shishido et al., 1997)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Fails to complement	htl¹⁰⁸ (Shishido et al., 1997) htl¹¹⁷ (Shishido et al., 1997) htl^S1-28 (Shishido et al., 1997)
Rescued by	Df(3R)sr16/htl⁸⁰ is rescued by htl^E12 (Shishido et al., 1997)
Comments	The lethality of htl⁸⁰/Df(3R)sr16 flies is rescued by htl^E12. (Shishido et al., 1997)
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	htl⁸⁰
Name Synonym
Secondary FlyBase IDs

References ( 2 )
Research paper	Kramer et al., 1999, Development 126(11): 2515--2525 Sprouty: a common antagonist of FGF and EGF signaling pathways in Drosophila. [FBrf0108521] Shishido et al., 1997, Development 124(11): 2119--2128 Requirements of DFR1/Heartless, a mesoderm-specific Drosophila FGF-receptor, for the formation of heart, visceral and somatic muscles, and ensheathing of longitudinal axon tracts in CNS. [FBrf0093724]

Allele Dmel\htl80

Allele Dmel\htl⁸⁰