FlyBase Allele Report: Scer\GAL4[Ntan1-Mz97]

FB2025_01 , released February 20, 2025

FB2025_01 , released February 20, 2025

Allele: Scer\GAL4^Ntan1-Mz97

General Information

Symbol

Scer\GAL4^Ntan1-Mz97

Species

S. cerevisiae

Name

FlyBase ID

FBal0061886

Feature type

allele

Associated gene

Associated Insertion(s)

P{GawB}Ntan1^Mz97

Carried in Construct

Also Known As

Mz97-Gal4, Mz97, Mz97Gal4

Allele class

Mutagen

Delta2-3 transposase

Nature of the Allele

Allele class

Mutagen

Delta2-3 transposase

(Ito et al., 1995)

Progenitor genotype

Associated Insertion(s)

P{GawB}Ntan1^Mz97

Cytology

Description

Allele components

Component

Use(s)

Inserted element

Encoded product / tool

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 14 -- 16

larval B-subperineurial glial cell

(Beckervordersandforth et al., 2008)

lateral ventral subperineurial glial cell

(Beckervordersandforth et al., 2008)

medial dorsal subperineurial glial cell

(Beckervordersandforth et al., 2008)

dorsal lateral subperineurial glial cell

(Beckervordersandforth et al., 2008)

ventral lateral subperineurial glial cell

Comment: in 10-50% of examined hemisegments

(Beckervordersandforth et al., 2008)

medial ventral subperineurial glial cell

(Beckervordersandforth et al., 2008)

dorsal channel glial cell

(Beckervordersandforth et al., 2008)

lateral intersegmental nerve root glial cell

(Beckervordersandforth et al., 2008)

larval glial cell | subset of first optic chiasma

(Edwards et al., 2012)

embryonic/larval wrapping glial cell

(Edwards et al., 2012)

first instar larval stage

glial cell of larval central nervous system

(Ito et al., 1995)

third instar larval stage

embryonic/larval wrapping glial cell of the eye disc

(Cameron et al., 2016, Silies et al., 2007)

embryonic/larval CNS subperineurial glial cell | subset

(Schmidt et al., 2012)

embryonic/larval wrapping glial cell | subset

(Schmidt et al., 2012)

embryonic/larval CNS subperineurial glial cell

(Zülbahar et al., 2018)

embryonic/larval optic stalk surface glial cell

(Cameron et al., 2016)

lamina anlage glial cell

(Cameron et al., 2016)

embryonic/larval wrapping glial cell

(Spéder and Brand, 2014)

third instar larval stage -- prepupal stage P4

embryonic/larval wrapping glial cell of the eye disc

(Yeh et al., 2018)

glial cell | subset of first optic chiasma

(Edwards et al., 2012)

developing satellite glial cell

(Edwards et al., 2012)

glial cell | subset of embryonic/larval optic lobe

(Edwards et al., 2012)

pupal stage P7 -- adult stage

pseudocartridge glial cell

(Yeh et al., 2018)

pharate adult stage -- adult stage

adult outer optic chiasma giant glial cell

(Edwards et al., 2012)

adult inner optic chiasma giant glial cell

(Edwards et al., 2012)

adult distal lamina satellite glial cell

(Edwards et al., 2012)

pseudocartridge glial cell

(Edwards et al., 2012)

Additional Information

Statement

Reference

Drives expression in wrapping and subperineurial glial cells, and in a subset of adult optic lobe glial cells.

(FlyBase Curators, 2017)

ScerGAL4^Mz97 drives expression in around 2.5 local interneurons with cell bodies in the ventral region of the antennal lobe. Projections of these bilateral neurons are detected to glomeruli V, VA5, VC3l, VL1, VL2a, VL2p, VM4, VP1, VP4, VP2, VP3 and the antennal lobe hub. Labeling is also detected in one cell body in the adult subesophageal zone. This neuron projects to glomeruli D, DA2, DL5, DM2, DM3, DM6, V, VA6, VC1, DA1, DA3, DA4l, DA4m, DC3, VA1s, VA1v, VC3l, VL2a, and DC4.

(Tanaka et al., 2012)

Expression in glial cells not exclusive, expressed in other tissues as well.

(Ito et al., 1995)

Marker for

embryonic/larval CNS perineurial glial cell

(Zülbahar et al., 2018)

embryonic/larval optic stalk surface glial cell

(Cameron et al., 2016)

embryonic/larval wrapping glial cell of the eye disc

(Cameron et al., 2016, Silies et al., 2007)

lamina anlage glial cell

(Cameron et al., 2016)

Reflects expression of

(Zülbahar et al., 2018, Beckervordersandforth et al., 2008)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

astrocyte-like glial cell | embryonic stage, with Sdc^{PA.UAS.Tag:FLAG,GFP}

(Stork et al., 2014)

embryonic/larval optic stalk | third instar larval stage, with bdl^GD2597

(Cameron et al., 2016)

embryonic/larval optic stalk | third instar larval stage, with bdl^UAS.Tag:FLAG

(Cameron et al., 2016)

embryonic/larval wrapping glial cell of the eye disc | third instar larval stage, with bdl^GD2597

(Cameron et al., 2016)

embryonic/larval wrapping glial cell of the eye disc | third instar larval stage, with bdl^UAS.Tag:FLAG

(Cameron et al., 2016)

embryonic/larval wrapping glial cell of the eye disc | third instar larval stage, with htl^GD84

(Cameron et al., 2016)

fascicle | third instar larval stage, with rau^UAS.cSa

(Sieglitz et al., 2013)

glial cell, with htl^λ.UAS

(Franzdóttir et al., 2009)

glial cell projection | embryonic stage, with Sdc^{PA.UAS.Tag:FLAG,GFP}

(Stork et al., 2014)

nucleus, with rpr^UAS.cUa

(Bates and Whitington, 2007)

oenocyte | somatic clone, with rpr^UAS.cUa

(Bates and Whitington, 2007)

PNS glial cell, with numb^UAS.cWa

(Edenfeld et al., 2007)

subperineurial glial cell, with dup^GD13203

(Unhavaithaya and Orr-Weaver, 2012)

Detailed Description

Statement

Reference

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

Scer\GAL4^Ntan1-Mz97, htl^GD84 has abnormal neuroanatomy | third instar larval stage phenotype, non-enhanceable by bdl^EX2/bdl[+]

(Cameron et al., 2016)

Scer\GAL4^Ntan1-Mz97, htl^GD84 has abnormal neuroanatomy | third instar larval stage phenotype, non-enhanceable by bdl^UAS.Tag:FLAG/Scer\GAL4^Ntan1-Mz97

(Cameron et al., 2016)

NOT suppressed by

Statement

Reference

Scer\GAL4^Ntan1-Mz97, htl^GD84 has abnormal neuroanatomy | third instar larval stage phenotype, non-suppressible by bdl^EX2/bdl[+]

(Cameron et al., 2016)

Scer\GAL4^Ntan1-Mz97, htl^GD84 has abnormal neuroanatomy | third instar larval stage phenotype, non-suppressible by bdl^UAS.Tag:FLAG/Scer\GAL4^Ntan1-Mz97

(Cameron et al., 2016)

NOT Enhancer of

Statement

Reference

bdl^UAS.Tag:FLAG/Scer\GAL4^Ntan1-Mz97 is a non-enhancer of abnormal neuroanatomy | third instar larval stage phenotype of Scer\GAL4^Ntan1-Mz97, htl^GD84

(Cameron et al., 2016)

NOT Suppressor of

Statement

Reference

bdl^UAS.Tag:FLAG/Scer\GAL4^Ntan1-Mz97 is a non-suppressor of abnormal neuroanatomy | third instar larval stage phenotype of Scer\GAL4^Ntan1-Mz97, htl^GD84

(Cameron et al., 2016)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

Scer\GAL4^Ntan1-Mz97, htl^GD84 has embryonic/larval wrapping glial cell of the eye disc | third instar larval stage phenotype, non-enhanceable by bdl^EX2/bdl[+]

(Cameron et al., 2016)

Scer\GAL4^Ntan1-Mz97, htl^GD84 has embryonic/larval wrapping glial cell of the eye disc | third instar larval stage phenotype, non-enhanceable by bdl^UAS.Tag:FLAG/Scer\GAL4^Ntan1-Mz97

(Cameron et al., 2016)

NOT suppressed by

Statement

Reference

Scer\GAL4^Ntan1-Mz97, htl^GD84 has embryonic/larval wrapping glial cell of the eye disc | third instar larval stage phenotype, non-suppressible by bdl^EX2/bdl[+]

(Cameron et al., 2016)

Scer\GAL4^Ntan1-Mz97, htl^GD84 has embryonic/larval wrapping glial cell of the eye disc | third instar larval stage phenotype, non-suppressible by bdl^UAS.Tag:FLAG/Scer\GAL4^Ntan1-Mz97

(Cameron et al., 2016)

NOT Enhancer of

Statement

Reference

bdl^UAS.Tag:FLAG/Scer\GAL4^Ntan1-Mz97 is a non-enhancer of embryonic/larval wrapping glial cell of the eye disc | third instar larval stage phenotype of Scer\GAL4^Ntan1-Mz97, htl^GD84

(Cameron et al., 2016)

NOT Suppressor of

Statement

Reference

bdl^UAS.Tag:FLAG/Scer\GAL4^Ntan1-Mz97 is a non-suppressor of embryonic/larval wrapping glial cell of the eye disc | third instar larval stage phenotype of Scer\GAL4^Ntan1-Mz97, htl^GD84

(Cameron et al., 2016)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Partially rescues

Scer\GAL4^Ntan1-Mz97/pyr^UAS.cKa partially rescues Df(2R)BSC25

(Stork et al., 2014)

ths^UAS.cSa/Scer\GAL4^Ntan1-Mz97 partially rescues Df(2R)BSC25

(Stork et al., 2014)

spin^I.UAS/Scer\GAL4^Ntan1-Mz97 partially rescues spin¹⁰⁴⁰³

(Yuva-Aydemir et al., 2011)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

9488

w^*; P{GawB}Ntan1^Mz97 P{UAS-Stinger}2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

GAL4^Mz97

Scer\GAL4^Mz97

Scer\GAL4^Ntan1-Mz97

Name Synonyms

Secondary FlyBase IDs

References (41)

Report Sections