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General Information
Symbol
Dmel\piounspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0062503
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Mutagen
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Many flies that contain mutant clones have pits or protrusions on the thorax in the vicinity of the flight muscle attachments.

When mutant clones are induced in the wing, a wing blister appears within a few minutes of eclosion of the adult flies from the pupal case.

Mutant clones in the pupal wing completely lack the transalar microtubule arrays that are normally seen spanning the wing cells at this stage. This results in an expansion of the mutant cells and a contraction of the wild-type cells in the opposing epithelial layer. The two epithelial sheets of the wing remain associated.

Homozygous embryos complete development but the tracheae appear twisted and broken and the cuticle detaches from the epidermis.

Homozygous clones in the wing produce large blisters that lack sharp boundaries. Wings are sometimes rumpled. Homozygous embryos show excessive contractions of the segmental muscles just before hatching. The posterior segments are compacted and the muscles appear shorter than normal.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement
Reference

pio[+]/piounspecified is an enhancer of visible | recessive phenotype of mys8

Phenotype Manifest In
NOT suppressed by
Statement
Reference

piounspecified has cytoplasmic microtubule & wing | somatic clone phenotype, non-suppressible by pio::torUAS.cBa/Scer\GAL4unspecified

Enhancer of
Statement
Reference

pio[+]/piounspecified is an enhancer of wing phenotype of mys8

Additional Comments
Genetic Interactions
Statement
Reference

The loss of the transalar microtubule arrays seen in piounspecified clones in the pupal wing is not rescued by expression of pio::torScer\UAS.cBa in the pupal wings under the control of Scer\GAL4unspecified.

Shows a weak genetic interaction with mys8; the frequency of held-out wings but not the frequency of blisters in mys8 single hemizygotes is increased if they are also heterozygous for piounspecified. Shows no interaction with mysb9.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Rescued by
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
piounspecified
unspecified
Name Synonyms
Secondary FlyBase IDs
    References (2)