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General Information
Symbol
Dmel\osa616
Species
D. melanogaster
Name
FlyBase ID
FBal0062860
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
point mutation
Nucleotide change:
C17708251T
Amino acid change:
Q338term | osa-PA; Q338term | osa-PB; Q338term | osa-PC; Q338term | osa-PD; Q338term | osa-PE; Q338term | osa-PF
Reported amino acid change:
Q338term
Comment:
Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Amino acid replacement: Q338term.
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Hemizygous mutant adults exhibit about 2.38 dorsocentral bristle per heminotum (compared to 2.00 in wild-type).
Dominant held out wing phenotype. Clones lead to scars and loss of retinal differentiation.
Clones induced on the wing disc produced early in development transforms the posterior notum into a partial second wing. The wings have reversed anterior-posterior polarity. Clones induced later in development are associated with ectopic wing margin bristles near the wing margin restricted to the dorsal surface of the anterior compartment.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement
Reference
osa[+]/osa616 is a suppressor of visible phenotype of roDOM
Phenotype Manifest In
Enhancer of
Statement
Reference
osa616 is an enhancer of thorax phenotype of ChiE
Suppressor of
Statement
Reference
osa616 is a suppressor of dorsocentral bristle phenotype of tou2
osa616 is a suppressor of dorsocentral bristle phenotype of ChiE
osa[+]/osa616 is a suppressor of eye phenotype of roDOM
Additional Comments
Genetic Interactions
Statement
Reference
tou2 ; osa616/+ flies exhibit an average of 1.97 dorsocentral bristles per heminotum, compared to 1.4 in tou2/+ flies and 2.0 in wild-type controls.
Strong suppressor of roDOM.
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
eld616
osa616
Name Synonyms
Secondary FlyBase IDs
    References (5)