Allele Dmel\Low¹

General Information
Symbol	Dmel\Low¹	Species	D. melanogaster
Name		FlyBase ID	FBal0063133
Feature type	allele	Associated gene	Dmel\Low

Allele class	loss of function allele
Mutagen	gamma ray
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class	loss of function allele (Bhadra et al., 1997)
Mutagen	gamma ray (Bhadra et al., 1997)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Cytology
Phenotypic Data
Phenotypic Class
	lethal \| recessive (Pal Bhadra et al., 1998, Bhadra et al., 1997) suppressor of variegation, with In(1)w^m4h (Bhadra et al., 1998) suppressor of variegation \| dominant, with In(1)w^m4h (Bhadra et al., 1997) suppressor of variegation \| dominant, with In(1)y^3P (Bhadra et al., 1997)
Phenotype Manifest In
	pigment cell (Pal Bhadra et al., 1998)
Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement Reference Low¹ is an enhancer of eye color defective \| recessive phenotype of w^bf2 (Bhadra et al., 1997) Low¹ is an enhancer of eye color defective \| recessive phenotype of w^bf (Bhadra et al., 1997) Low¹ is an enhancer of eye color defective \| recessive phenotype of w^bl (Bhadra et al., 1997) Low¹ is an enhancer of eye color defective phenotype of w^DZL (Bhadra et al., 1997)
Suppressor of
Statement Reference Low[+]/Low¹ is a suppressor of visible phenotype of B^unspecified (Bhadra et al., 1997) Low¹ is a suppressor of eye color defective \| recessive phenotype of w^a2 (Bhadra et al., 1997) Low¹ is a suppressor of eye color defective \| recessive phenotype of w^a3 (Bhadra et al., 1997) Low¹ is a suppressor of eye color defective \| recessive phenotype of w^a (Bhadra et al., 1997) Low¹ is a suppressor of eye color defective \| recessive phenotype of w^Adh.PB (Bhadra et al., 1997) Low¹ is a suppressor of eye color defective \| recessive phenotype of w^Bwx (Bhadra et al., 1997) Low¹ is a suppressor of eye color defective \| recessive phenotype of w^cf (Bhadra et al., 1997) Low¹ is a suppressor of eye color defective \| recessive phenotype of w^co (Bhadra et al., 1997) Low¹ is a suppressor of eye color defective \| recessive phenotype of w^col (Bhadra et al., 1997) Low¹ is a suppressor of eye color defective \| recessive phenotype of w^h (Bhadra et al., 1997) Low¹ is a suppressor of eye color defective \| recessive phenotype of w^IR1 (Bhadra et al., 1997) Low¹ is a suppressor of eye color defective \| recessive phenotype of w^IR2 (Bhadra et al., 1997) Low¹ is a suppressor of eye color defective \| recessive phenotype of w^IR3 (Bhadra et al., 1997) Low¹ is a suppressor of eye color defective \| recessive phenotype of w^IR4 (Bhadra et al., 1997) Low¹ is a suppressor of eye color defective \| recessive phenotype of w^IR5 (Bhadra et al., 1997) Low¹ is a suppressor of eye color defective \| recessive phenotype of w^IR6 (Bhadra et al., 1997) Low¹ is a suppressor of eye color defective \| recessive phenotype of w^sat (Bhadra et al., 1997) Low¹ is a suppressor of eye color defective \| recessive phenotype of w^sp55 (Bhadra et al., 1997) Low¹ is a suppressor of visible \| dominant phenotype of L^unspecified (Bhadra et al., 1997)
NOT Suppressor of
Statement Reference Low¹ is a non-suppressor of lethal \| female phenotype of Sxl^fhv1/Sxl^f1 (Bhadra et al., 1997) Low¹ is a non-suppressor of lethal \| recessive \| male phenotype of msl-3^unspecified (Bhadra et al., 1997)
Other
Statement Reference Low¹, w^a, z¹ has eye color defective phenotype (Bhadra et al., 1997)
Phenotype Manifest In
Suppressed by
Statement Reference Low¹ has phenotype, suppressible by Wow^γb (Pal Bhadra et al., 1998)
Enhancer of
Statement Reference Low¹/Inr-a^EMS2 is an enhancer of phenotype of w^sp1 (Bhadra et al., 1998) Low¹ is an enhancer of pigment cell phenotype of w^bf2 (Bhadra et al., 1997) Low¹ is an enhancer of pigment cell phenotype of w^bf (Bhadra et al., 1997) Low¹ is an enhancer of pigment cell phenotype of w^bl (Bhadra et al., 1997) Low¹ is an enhancer of pigment cell phenotype of w^DZL (Bhadra et al., 1997) Mow^EMS/Low¹ is an enhancer of phenotype of w^crr (Bhadra et al., 1998) Wow^unspecified, Mow^EMS, Low¹, Inr-a^EMS2 is an enhancer of phenotype of w^sp1 (Bhadra et al., 1998) Wow^unspecified/Low¹ is an enhancer of phenotype of w^sp1 (Bhadra et al., 1998)
NOT Enhancer of
Statement Reference Low[+]/Low¹ is a non-enhancer of phenotype of r^sP1 (Bhadra et al., 1997) Low[+]/Low¹ is a non-enhancer of phenotype of RpII215⁹⁶ (Bhadra et al., 1997) Low¹ is a non-enhancer of eye phenotype of Dr^unspecified (Bhadra et al., 1997) Low¹ is a non-enhancer of eye phenotype of Kr^If-1 (Bhadra et al., 1997) Low¹ is a non-enhancer of phenotype of w^-113 (Bhadra et al., 1997) Low¹ is a non-enhancer of phenotype of w^+mC (Bhadra et al., 1997) Low¹ is a non-enhancer of phenotype of w^+mF (Bhadra et al., 1997) Low¹ is a non-enhancer of phenotype of w^+mSC (Bhadra et al., 1997) Low¹ is a non-enhancer of phenotype of w^a4 (Bhadra et al., 1997) Low¹ is a non-enhancer of phenotype of w^a59k1 (Bhadra et al., 1997) Low¹ is a non-enhancer of phenotype of w^aM (Bhadra et al., 1997) Low¹ is a non-enhancer of phenotype of w^ap-1 (Bhadra et al., 1997) Low¹ is a non-enhancer of phenotype of w^aR84h (Bhadra et al., 1997) Low¹ is a non-enhancer of phenotype of w^BgB+173 (Bhadra et al., 1997) Low¹ is a non-enhancer of phenotype of w^c (Bhadra et al., 1997) Low¹ is a non-enhancer of phenotype of w^E (Bhadra et al., 1997) Low¹ is a non-enhancer of phenotype of w^e (Bhadra et al., 1997) Low¹ is a non-enhancer of phenotype of wⁱ (Bhadra et al., 1997) Low¹ is a non-enhancer of phenotype of w^ric (Bhadra et al., 1997) Low¹ is a non-enhancer of phenotype of w^sp1 (Bhadra et al., 1998, Bhadra et al., 1997) Low¹ is a non-enhancer of phenotype of w^sp2 (Bhadra et al., 1997) Low¹ is a non-enhancer of phenotype of w^sp3 (Bhadra et al., 1997) Low¹ is a non-enhancer of phenotype of w^sp4 (Bhadra et al., 1997) Low¹ is a non-enhancer of phenotype of w^sp81d (Bhadra et al., 1997) Low¹ is a non-enhancer of phenotype of w^Z4-17 (Bhadra et al., 1997) Low¹ is a non-enhancer of phenotype of w^zm (Bhadra et al., 1997) Low¹ is a non-enhancer of phenotype of z¹ (Bhadra et al., 1998) Mow^EMS, Low¹, Inr-a^EMS2 is a non-enhancer of phenotype of w^sp1 (Bhadra et al., 1998) Mow^EMS/Low¹ is a non-enhancer of phenotype of w^sp1 (Bhadra et al., 1998) Wow^unspecified, Low¹, Inr-a^EMS2 is a non-enhancer of phenotype of w^sp1 (Bhadra et al., 1998) z¹/Low¹ is a non-enhancer of phenotype of w^is (Bhadra et al., 1997)
Suppressor of
Statement Reference Low[+]/Low¹ is a suppressor of eye phenotype of B^unspecified (Bhadra et al., 1997) Low¹/Inr-a^EMS2 is a suppressor of phenotype of w^crr (Bhadra et al., 1998) Low¹ is a suppressor of eye phenotype of L^unspecified (Bhadra et al., 1997) Low¹ is a suppressor of phenotype of w^a (Pal Bhadra et al., 1998) Low¹ is a suppressor of phenotype of w^crr (Bhadra et al., 1998) Low¹ is a suppressor of phenotype of Wow^γb (Pal Bhadra et al., 1998) Low¹ is a suppressor of pigment cell phenotype of w^a2 (Bhadra et al., 1997) Low¹ is a suppressor of pigment cell phenotype of w^a3 (Bhadra et al., 1997) Low¹ is a suppressor of pigment cell phenotype of w^a (Bhadra et al., 1997) Low¹ is a suppressor of pigment cell phenotype of w^Adh.PB (Bhadra et al., 1997) Low¹ is a suppressor of pigment cell phenotype of w^Bwx (Bhadra et al., 1997) Low¹ is a suppressor of pigment cell phenotype of w^cf (Bhadra et al., 1997) Low¹ is a suppressor of pigment cell phenotype of w^co (Bhadra et al., 1997) Low¹ is a suppressor of pigment cell phenotype of w^col (Bhadra et al., 1997) Low¹ is a suppressor of pigment cell phenotype of w^h (Bhadra et al., 1997) Low¹ is a suppressor of pigment cell phenotype of w^IR1 (Bhadra et al., 1997) Low¹ is a suppressor of pigment cell phenotype of w^IR2 (Bhadra et al., 1997) Low¹ is a suppressor of pigment cell phenotype of w^IR3 (Bhadra et al., 1997) Low¹ is a suppressor of pigment cell phenotype of w^IR4 (Bhadra et al., 1997) Low¹ is a suppressor of pigment cell phenotype of w^IR5 (Bhadra et al., 1997) Low¹ is a suppressor of pigment cell phenotype of w^IR6 (Bhadra et al., 1997) Low¹ is a suppressor of pigment cell phenotype of w^sat (Bhadra et al., 1997) Low¹ is a suppressor of pigment cell phenotype of w^sp55 (Bhadra et al., 1997) Mow^EMS, Low¹, Inr-a^EMS2 is a suppressor of phenotype of w^crr (Bhadra et al., 1998) w^a/Low¹ is a suppressor of phenotype of z¹ (Bhadra et al., 1997) Wow^unspecified, Low¹, Inr-a^EMS2 is a suppressor of phenotype of w^crr (Bhadra et al., 1998) Wow^unspecified, Mow^EMS, Low¹, Inr-a^EMS2 is a suppressor of phenotype of w^crr (Bhadra et al., 1998) Wow^unspecified, Mow^EMS, Low¹ is a suppressor of phenotype of w^crr (Bhadra et al., 1998) Wow^unspecified, Mow^EMS, Low¹ is a suppressor of phenotype of w^sp1 (Bhadra et al., 1998) Wow^unspecified/Low¹ is a suppressor of phenotype of w^crr (Bhadra et al., 1998)
NOT Suppressor of
Statement Reference Low[+]/Low¹ is a non-suppressor of phenotype of r^sP1 (Bhadra et al., 1997) Low[+]/Low¹ is a non-suppressor of phenotype of RpII215⁹⁶ (Bhadra et al., 1997) Low¹ is a non-suppressor of eye phenotype of Dr^unspecified (Bhadra et al., 1997) Low¹ is a non-suppressor of eye phenotype of Kr^If-1 (Bhadra et al., 1997) Low¹ is a non-suppressor of phenotype of w^-113 (Bhadra et al., 1997) Low¹ is a non-suppressor of phenotype of w^+mC (Bhadra et al., 1997) Low¹ is a non-suppressor of phenotype of w^+mF (Bhadra et al., 1997) Low¹ is a non-suppressor of phenotype of w^+mSC (Bhadra et al., 1997) Low¹ is a non-suppressor of phenotype of w^a4 (Bhadra et al., 1997) Low¹ is a non-suppressor of phenotype of w^a59k1 (Bhadra et al., 1997) Low¹ is a non-suppressor of phenotype of w^aM (Bhadra et al., 1997) Low¹ is a non-suppressor of phenotype of w^ap-1 (Bhadra et al., 1997) Low¹ is a non-suppressor of phenotype of w^aR84h (Bhadra et al., 1997) Low¹ is a non-suppressor of phenotype of w^BgB+173 (Bhadra et al., 1997) Low¹ is a non-suppressor of phenotype of w^c (Bhadra et al., 1997) Low¹ is a non-suppressor of phenotype of w^e (Bhadra et al., 1997) Low¹ is a non-suppressor of phenotype of w^E (Bhadra et al., 1997) Low¹ is a non-suppressor of phenotype of wⁱ (Bhadra et al., 1997) Low¹ is a non-suppressor of phenotype of w^ric (Bhadra et al., 1997) Low¹ is a non-suppressor of phenotype of w^sp1 (Bhadra et al., 1998, Bhadra et al., 1997) Low¹ is a non-suppressor of phenotype of w^sp2 (Bhadra et al., 1997) Low¹ is a non-suppressor of phenotype of w^sp3 (Bhadra et al., 1997) Low¹ is a non-suppressor of phenotype of w^sp4 (Bhadra et al., 1997) Low¹ is a non-suppressor of phenotype of w^sp81d (Bhadra et al., 1997) Low¹ is a non-suppressor of phenotype of w^Z4-17 (Bhadra et al., 1997) Low¹ is a non-suppressor of phenotype of w^zm (Bhadra et al., 1997) Low¹ is a non-suppressor of phenotype of z¹ (Bhadra et al., 1997, Bhadra et al., 1998) Mow^EMS, Low¹, Inr-a^EMS2 is a non-suppressor of phenotype of w^sp1 (Bhadra et al., 1998) Mow^EMS/Low¹ is a non-suppressor of phenotype of w^sp1 (Bhadra et al., 1998) w^is/Low¹ is a non-suppressor of phenotype of z¹ (Bhadra et al., 1997) Wow^unspecified, Low¹, Inr-a^EMS2 is a non-suppressor of phenotype of w^sp1 (Bhadra et al., 1998) z¹/Low¹ is a non-suppressor of phenotype of w^is (Bhadra et al., 1997)
Other
Statement Reference Low¹, w^a, z¹ has eye phenotype (Bhadra et al., 1997) Low¹, w^a, z¹ has pigment cell phenotype (Bhadra et al., 1997)
Additional Comments
Genetic Interactions
Statement Reference Low¹ mutants suppress mutant eye colour phenotype in w^crr mutants and has no effect on mutant eye colour phenotype in w^sp1 mutants. Low¹, Wow^unspecified mutants suppress mutant eye colour phenotype in w^crr mutants and enhance mutant eye colour phenotype in w^sp1 mutants. Low¹, Mow^EMS mutants enhance mutant eye colour phenotype in w^crr mutants and have no effect on mutant eye colour phenotype in w^sp1 mutants. Low¹, Inr-a^EMS2 mutants suppress mutant eye colour phenotype in w^crr mutants and enhance mutant eye colour phenotype in w^sp1 mutants. Low¹, Inr-a^EMS2, Wow^unspecified mutants suppress mutant eye colour phenotype in w^crr mutants and have no effect on mutant eye colour phenotype in w^sp1 mutants. Low¹, Inr-a^EMS2, Mow^EMS mutants suppress mutant eye colour phenotype in w^crr mutants and have no effect on mutant eye colour phenotype in w^sp1 mutants. Low¹, Wow^unspecified, Mow^EMS mutants suppress mutant eye colour phenotype in w^crr and w^sp1 mutants. Low¹, Inr-a^EMS2, Wow^unspecified, Mow^EMS mutants suppress mutant eye colour phenotype in w^crr mutants and enhance mutant eye colour phenotype in w^sp1 mutants. (Bhadra et al., 1998) Low¹ is epistatic to Mow^EMS. Low¹ and Wow^γb mutually suppress the effect of the other. (Pal Bhadra et al., 1998) The lethality of Sxl^f1/Sxl^fhv1 females or msl-3^unspecified/msl-3^unspecified males is not affected by Low¹. The eye colour phenotype of w^a4, w^ric, w^aM, w^aR84h, w^a59k1, wⁱ, w^c, w^sp1, w^sp3, w^sp4, w^sp2, w^sp81d, w^e, w^ap-1, z¹ w^is, z¹ w^zm, z¹ Dp(1;1)w⁺61e19, w^E, w^+mF, w^+mSC, w^-113, w^Z4-17, w^+mC and w^BgB+173 flies is unaffected by a single copy of Low¹. (Bhadra et al., 1997)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Low¹ unnamed (Pal Bhadra et al., 1998, Bhadra et al., 1998, Bhadra et al., 1997)
Name Synonym
Secondary FlyBase IDs

References ( 3 )
Research paper	Bhadra et al., 1998, Genetics 150(1): 251--263 Interactions among dosage-dependent trans-acting modifiers of gene expression and position-effect variegation in Drosophila. [FBrf0104408] Pal Bhadra et al., 1998, Mol. Gen. Genet. 259(2): 198--206 Role of multiple trans-acting regulators in modifying the effect of the retrotransposon copia on host gene expression in Drosophila. [FBrf0104493] Bhadra et al., 1997, Genetics 146(3): 903--917 A sex-influenced modifier in Drosophila that affects a broad spectrum of target loci including the histone repeats. [FBrf0094158]

Allele Dmel\Low1

Allele Dmel\Low¹