|Feature type||allele||Associated gene||Dmel\Asx|
|Allele class||loss of function allele|
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|Nature of the Allele|
|Mutations Mapped to the Genome|
|Associated Sequence Data|
|Nature of the lesion|
|Phenotype Manifest In|
Homozygous Asx[xen-72-3] mutant clones cause wing defects. The abnormalities include wing blisters, crumpling of the wing, bending or folding of the wing along the mutant clone, and dual-lobed wings. Patches of necrotic cells associated with Asx[xen-72-3] mutant clones can be observed at low frequency. Asx[xen-72-3] mutant clone adult wings have patched of small cells containing more than one hair.
Homozygotes die as early larvae. Homozygous clones in the wing produce discrete, round blisters of variable size. These blisters can be located anywhere on the wing. Wing venation is normal. Homozygous embryos show no gross morphological abnormalities at hatching. Hatched larvae fail to grow.
Homozygous clones in the wing produce a blistered phenotype.
|Phenotype Manifest In|
The severity of wing phenotypes caused by homozygous Asx[xen-72-3] mutant clones is reduced in a heterozygous Ubx[unspecified] mutant background. For example, no necrotic or dual-lobed wings are observed. In addition, the percentage of wing blisters or folded/bent wings is reduced and fewer flies have crumpled wings. In some cases, ripples are associated with visible clones containing small cells, whereas other ripples are not associated with the presence of smaller cells.
|Complementation & Rescue Data|
|Fails to complement|
|Stocks ( 1 )|
|Notes on Origin|
|External Crossreferences & Linkouts|
|Synonyms & Secondary IDs ( 5 )|
|Secondary FlyBase IDs|
|References ( 3 )|
|Personal communication to FlyBase|