FB2025_01 , released February 20, 2025
Allele: Dmel\cosk16101
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General Information
Symbol
Dmel\cosk16101
Species
D. melanogaster
Name
FlyBase ID
FBal0064070
Feature type
allele
Associated gene
Dmel\cos
Associated Insertion(s)
P{lacW}cosk16101
Carried in Construct
Also Known As
cos2k16101, l(2)k16101
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Roch et al., 1998, BDGP Project Members, 1994-1999)
Progenitor genotype
Associated Insertion(s)
P{lacW}cosk16101
Cytology
Description

P{lacW} element 30bp downstream of the 5' end of the transcribed region.

(Liu and Montell, 1999)
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      exacerbates  amyotrophic lateral sclerosis type 8
      modeled by Vap33P58S.UAS.Tag:FLAG
      (Sanhueza et al., 2015)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Heterozygotes show a direct effect on the shape of the wing.

      (Dworkin and Gibson, 2006)

      Lethality occurs during third instar larval or pupal stages. Mutants exhibit visible disc abnormalities.

      (Roch et al., 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer

      I. Kiss.

      (BDGP Project Members, 1994-1999)
      Comments
      Comments

      Complements: l(2)43Bb04614a. Complements: Dscam05518.

      (BDGP Project Members, 1994-1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (8)
      Reported As
      Symbol Synonym
      161/1
      (Roch et al., 1998)
      Cos2k16101
      (Moore et al., 2022, Giordani et al., 2016)
      cos2k16101
      (Christiansen et al., 2013, Nakano et al., 2004)
      cosK16101
      (Dworkin and Gibson., 2006)
      cosk16101
      k16101
      (Dworkin and Gibson, 2006)
      l(2)k16101
      (Liu and Montell, 1999, Spradling et al., 1999)
      l(2)k16101k16101
      Name Synonyms
      Secondary FlyBase IDs
        References (11)