FB2025_01 , released February 20, 2025
Allele: Dmel\tefk15914
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General Information
Symbol
Dmel\tefk15914
Species
D. melanogaster
Name
FlyBase ID
FBal0064073
Feature type
allele
Associated gene
Dmel\tef
Associated Insertion(s)
P{lacW}tefk15914
Carried in Construct
Key Links
Genomic Maps

Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Arya et al., 2006)
Mutagen
P-element activity
(BDGP Project Members, 1994-1999)
Progenitor genotype
Associated Insertion(s)
P{lacW}tefk15914
Cytology
Description

The P{lacW}tefk15914 insertion maps within the first exon of the tef gene, which itself is entirely contained within the first intron of fat-spondin. The processed mRNA of tef is wild type, despite the insertion being within the coding region (after nucleotide position 318 in the first exon).

(Arya et al., 2006)
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous males are wild-type with respect to fourth chromosome non-disjunction, while tefZ5864/tefk15914 males show a low level (4.3%) of fourth chromosome non-disjunction.

      (Arya et al., 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer

      I. Kiss.

      (BDGP Project Members, 1994-1999)

      Although the P{lacW}tefk15914 line was originally characterised as a lethal insertion, a viable line of flies homozygous for P{lacW}tefk15914 has been established.

      (Arya et al., 2006)
      Comments
      Comments

      Complements: RhoGEF204291. Complements: l(2)0625306253. Complements: l(2)k09303k09303. Complements: l(2)k11502k11502.

      (BDGP Project Members, 1994-1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      k15914
      (Ryder et al., 2004)
      l(2)k15914
      (Spradling et al., 1999)
      l(2)k15914k15914
      tefk15914
      tefl(2)k15914
      (Arya et al., 2006)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)