Allele Dmel\tef^k15914

General Information
Symbol	Dmel\tef^k15914	Species	D. melanogaster
Name		FlyBase ID	FBal0064073
Feature type	allele	Associated gene	Dmel\tef

Map ( GBrowse )	Untitled Document
Allele class	hypomorphic allele - genetic evidence
Mutagen	P-element activity
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class	hypomorphic allele - genetic evidence (Arya et al., 2006)
Mutagen	P-element activity (BDGP Project Members, 1994-1999)
Mutations Mapped to the Genome

Type Location Additional Notes References transposable element insertion site 2R:12,943,921..12,943,921 (BDGP Project Members, 1994-1999, Tomkiel, 2001.12.6, Spradling et al., 1999, Arya et al., 2006)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Insertion within the first exon, after nucleotide position 318. Although the insertion is within the coding region, the processed mRNA is wild type. (Arya et al., 2006)
Caused by insertion	P{lacW}tef^k15914 (BDGP Project Members, 1994-1999, Tomkiel, 2001.12.6, Spradling et al., 1999, Arya et al., 2006)
Cytology
Phenotypic Data
Phenotypic Class
	lethal \| recessive (Spradling et al., 1999, BDGP Project Members, 1994-1999) viable (Arya et al., 2006)
Phenotype Manifest In

Detailed Description
	Statement Reference Homozygous males are wild-type with respect to fourth chromosome non-disjunction, while tef^Z5864/tef^k15914 males show a low level (4.3%) of fourth chromosome non-disjunction. (Arya et al., 2006)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Fails to complement	tef^k15915 (BDGP Project Members, 1994-1999) tef^Z5864 (Arya et al., 2006)
Comments
Stocks ( 2 )
Bloomington	11150 y¹ w^67c23; P{lacW}tef^k15914 fat-spondin^k15914/CyO
Kyoto	111350 y^d2 w¹¹¹⁸ P{ey-FLP.N}2 P{GMR-lacZ.C(38.1)}TPN1; P{neoFRT}42D P{lacW}tef^k15914 /CyO y⁺
Notes on Origin
Discoverer	I. Kiss.
	Associated with: fat-spondin^k15914. (Arya et al., 2006) The P{lacW}tef^k15914 insertion maps within the first exon of tef, which itself is entirely contained within the first intron of fat-spondin. (Arya et al., 2006) Although the P{lacW}tef^k15914 line was originally characterised as a lethal insertion, a viable line of flies homozygous for P{lacW}tef^k15914 has been established. (Arya et al., 2006)
Comments
	Complements: RhoGEF2⁰⁴²⁹¹. Complements: l(2)06253⁰⁶²⁵³. Complements: l(2)k09303^k09303. Complements: l(2)k11502^k11502. (BDGP Project Members, 1994-1999)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym	k15914 (Ryder et al., 2004) l(2)k15914 (Spradling et al., 1999) l(2)k15914^k15914 tef^k15914 tef^l(2)k15914 (Arya et al., 2006)
Name Synonym
Secondary FlyBase IDs

References ( 5 )
Research paper	Arya et al., 2006, Genetics 174(1): 125--134 Molecular characterization of teflon, a gene required for meiotic autosome segregation in male Drosophila melanogaster. [FBrf0194210] Ryder et al., 2004, Genetics 167(2): 797--813 The DrosDel collection: a set of P-element insertions for generating custom chromosomal aberrations in Drosophila melanogaster. [FBrf0179424] Spradling et al., 1999, Genetics 153(1): 135--177 The Berkeley Drosophila genome project gene disruption project. Single P-element insertions mutating 25% of vital Drosophila genes. [FBrf0111489]
Personal communication to FlyBase	Tomkiel, 2001.12.6, Df(2R)P803-delta15. Df(2R)P803-delta15. [FBrf0141808] BDGP Project Members, 1994-1999, BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project. (Computer file) BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project. (Computer file) [FBrf0067338]

Allele Dmel\tefk15914

Allele Dmel\tef^k15914