FB2025_01 , released February 20, 2025
Allele: Dmel\Gγ1k08017
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General Information
Symbol
Dmel\Gγ1k08017
Species
D. melanogaster
Name
FlyBase ID
FBal0064352
Feature type
allele
Associated gene
Dmel\Gγ1
Associated Insertion(s)
P{lacW}Gγ1k08017
Carried in Construct
Also Known As
l(2)k08017
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(BDGP Project Members, 1994-1999)
Progenitor genotype
Associated Insertion(s)
P{lacW}Gγ1k08017
Cytology
Description

Insertion into the splice donor site after the first exon of Gγ1.

(Yi et al., 2006)
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Germ cell migration is normal in Gγ1k08017 homozygous embryos.

      (Ricardo and Lehmann, 2009)

      Homozygous and Gγ1k08017/Df(2R)H3E1 stage 17 embryos show a "broken hearted" phenotype; the pericardial cells are dissociated from cardioblasts in the dorsal vessel.

      (Yi et al., 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Ggamma1[+]/Gγ1k08017 is a suppressor of abnormal mitotic cell cycle phenotype of GαoUAS.cKa, Scer\GAL4Bx-MS1096

      (Katanaev and Tomlinson, 2006)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Ggamma1[+]/Gγ1k08017 is a suppressor of wing margin bristle phenotype of GαoUAS.cKa, Scer\GAL4Bx-MS1096

      (Katanaev and Tomlinson, 2006)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Overexpressed G-oα47AScer\UAS.cKa, under the control of Scer\GAL4Bx-MS1096 induces division defects that are attenuated by the removal of one copy of Gγ1k08017. The effects of overexpression of G-oα47AScer\UAS.cKa under the control of Scer\GAL4Bx-MS1096 are attenuated in Gγ1k08017 heterozygotes.

      (Katanaev and Tomlinson, 2006)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (4)
      Notes on Origin
      Discoverer

      I. Kiss.

      (BDGP Project Members, 1994-1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      Gg1k0817
      (Boyle and Berg, 2007)
      Gγ1K08017
      (Izumi et al., 2004)
      Gγ1k08017
      (Ricardo and Lehmann, 2009, Yi, 2006)
      l(2)k08017
      (Yi et al., 2006, Dockendorff et al., 2000, Spradling et al., 1999)
      l(2)k08017k08017
      (BDGP Project Members, 1994-1999)
      Name Synonyms
      Secondary FlyBase IDs
        References (10)