FlyBase Allele Report: Dmel\cass[k06710]

General Information

Symbol

Dmel\cass^k06710

Species

D. melanogaster

Name

FlyBase ID

FBal0064421

Feature type

allele

Associated gene

Dmel\cass

Associated Insertion(s)

P{lacW}cass^k06710

Carried in Construct

Also Known As

l(2)k06710

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(BDGP Project Members, 1994-1999)

Progenitor genotype

Associated Insertion(s)

P{lacW}cass^k06710

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2L:17,477,699..17,477,699 [+]

(Morris et al., 2006, Beaton, 2000.1.31, Spradling et al., 1999, BDGP Project Members, 1994-1999)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal (with Df(2L)BSC148)

(Kahsai and Cook, 2018)

lethal | recessive

(Beaton, 2000.1.31, Spradling et al., 1999, BDGP Project Members, 1994-1999)

visible, with Scer\GAL4^Act88F.PD, cass^RNAi.UAS

(Morris et al., 2006)

visible, with Scer\GAL4^ap-md544, cass^RNAi.UAS

(Morris et al., 2006)

visible, with Scer\GAL4^en-e16E, cass^RNAi.UAS

(Morris et al., 2006)

Phenotype Manifest In

wing blade, with Scer\GAL4^Act88F.PD, cass^RNAi.UAS

(Morris et al., 2006)

wing blade, with Scer\GAL4^ap-md544, cass^RNAi.UAS

(Morris et al., 2006)

wing blade, with Scer\GAL4^en-e16E, cass^RNAi.UAS

(Morris et al., 2006)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

cass^k06710 is an enhancer of visible phenotype of E2f1^UAS.cNa, Scer\GAL4^Act88F.PD

(Morris et al., 2006)

cass^k06710 is an enhancer of visible phenotype of E2f1^UAS.cNa, Scer\GAL4^nanos.PG

(Morris et al., 2006)

cass^k06710 is an enhancer of visible phenotype of E2f1^UAS.cNa, Scer\GAL4^GMR.PF

(Morris et al., 2006)

Phenotype Manifest In

Enhancer of

Statement

Reference

cass^k06710 is an enhancer of wing blade phenotype of E2f1^UAS.cNa, Scer\GAL4^Act88F.PD

(Morris et al., 2006)

cass^k06710 is an enhancer of macrochaeta phenotype of E2f1^UAS.cNa, Scer\GAL4^nanos.PG

(Morris et al., 2006)

cass^k06710 is an enhancer of eye phenotype of E2f1^UAS.cNa, Scer\GAL4^GMR.PF

(Morris et al., 2006)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

cass^k07112

(BDGP Project Members, 1994-1999)

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

10645

y¹ w^67c23; P{lacW}cass^k06710/CyO

Kyoto

111203

y^d2 w¹¹¹⁸ P{ey-FLP.N}2 P{5xglBS-lacZ.38-1}TPN1; P{lacW}cass^k06710 P{neoFRT}40A/CyO y⁺

Notes on Origin

Discoverer

I. Kiss.

(BDGP Project Members, 1994-1999)

Comments

After six generations of outcrossing the lethality continued to segragate with the P{lacW} insertion.

(Beaton, 2000.1.31)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

Aac11 l(2)k06710

(Morris et al., 2006)

Aac11^k06710

(Kahsai and Cook, 2018)

cass^k06710

l(2)k06710

(Spradling et al., 1999)

l(2)k06710^k06710

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

Open Close