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General Information
Symbol
Dmel\Nop60Bk05318
Species
D. melanogaster
Name
FlyBase ID
FBal0064499
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
l(2)k05318, mfl05
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

P{PZ} insertion within the first intron.

Insertion components
P{lacW}Nop60Bk05318
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Nop60Bk05318 mutant clones in the wing disc are much smaller or completely missing compared to control clones. In a minute background, clones are recovered in the larval wing disc of a similar size to control clones, but mutant clones are much reduced in size compared to control clones in the adult wing. Cell disorganisation is observed in mutant wing tissue.

Homozygotes mainly die as first instar larvae. They fail to increase their size compared to control siblings and remain as first instar larvae for an additional 4-5 days.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Partially rescued by
Comments

Expression of Nop60Bhs.PG using heat shock rescues 30% of Nop60Bk05318 animals to the pupal stage. The rescued animals develop synchronously with their control siblings and show a normal increase in size.

Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
Comments
Comments

Complements: bs03267. Complements: spagk12101. Complements: Zfrp8k13705. Complements: l(2)rQ313rQ313.

External Crossreferences and Linkouts ( 1 )
Crossreferences
GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
Synonyms and Secondary IDs (4)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (8)