FB2025_02 , released April 17, 2025
Allele: Dmel\l(2)k04222bk04222b
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General Information
Symbol
Dmel\l(2)k04222bk04222b
Species
D. melanogaster
Name
FlyBase ID
FBal0064540
Feature type
allele
Associated gene
l(2)k04222b
Associated Insertion(s)
P{lacW}l(2)k04222bk04222b
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(BDGP Project Members, 1994-1999)
Progenitor genotype
Associated Insertion(s)
P{lacW}l(2)k04222bk04222b
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      l(2)k04222bk04222b/l(2)k04222b[+] is a suppressor of visible phenotype of DysRNAi.NH2.UAS, Scer\GAL4Act.PU

      (Kucherenko et al., 2008)

      l(2)k04222bk04222b/l(2)k04222b[+] is a suppressor of visible phenotype of DysRNAi.C.UAS, Scer\GAL4Tub.PU

      (Kucherenko et al., 2008)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      l(2)k04222bk04222b/l(2)k04222b[+] is a suppressor of posterior crossvein phenotype of DysRNAi.NH2.UAS, Scer\GAL4Act.PU

      (Kucherenko et al., 2008)

      l(2)k04222bk04222b/l(2)k04222b[+] is a suppressor of posterior crossvein phenotype of DysRNAi.C.UAS, Scer\GAL4Tub.PU

      (Kucherenko et al., 2008)
      Other
      Statement
      Reference

      DysRNAi.C.UAS, l(2)k04222bk04222b/l(2)k04222b[+] has wing vein | ectopic phenotype

      (Kucherenko et al., 2008)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      One copy of l(2)k04222bk04222b strongly suppresses the detached posterior crossvein phenotype seen when DysdsRNA.NH2.Scer\UAS is expressed under the control of Scer\GAL4Act.PU.

      One copy of l(2)k04222bk04222b strongly suppresses the detached posterior crossvein phenotype seen when DysdsRNA.C.Scer\UAS is expressed under the control of Scer\GAL4tub.PU but produces extra wing vein material.

      (Kucherenko et al., 2008)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      I. Kiss.

      (BDGP Project Members, 1994-1999)
      Comments
      Comments

      Complements l(2)0712907129. The P{PZ}l(2)0712907129 insertion is at the same site as the P{lacW}mblk07110 and P{lacW}l(2)k04222bk04222b insertions.

      (Misra, 2000.11.18)

      Complements: mbl01038. Complements: l(2)0712907129. Complements: mblk01212. Complements: l(2)k07110k07110. Complements: l(2)k10914k10914.

      (BDGP Project Members, 1994-1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      l(2)k04222b
      (Misra, 2000.11.18, Spradling et al., 1999)
      l(2)k04222bk04222b
      Name Synonyms
      Secondary FlyBase IDs
        References (4)