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General Information
Symbol
Dmel\rigk07917
Species
D. melanogaster
Name
FlyBase ID
FBal0064711
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
l(2)k07917
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Insertion components
P{lacW}rigk07917
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of rigScer\UAS.T:Avic\GFP-ECFP driven by Scer\GAL4da.PU induces supernumerary bodies that are largely nuclear in larval muscles; these foci are reduced and mostly restricted to cytoplasm in a rig05056/rigk07917 background.

There first stage at which significant lethality of rigk07917/Df(2R)exu1 or rigk07917/rigk07839 animals occurs is the 2nd instar. Of those mutants that die as second instar larvae approximately half survive two or more days past the time when they should have molted to the third instar and obtain the size of a late third instar, but retain the anterior spiracles of a second instar larva. These larvae usually become stationary and die around the same time as their third instar siblings. Some mutants enter the 2nd to 3rd instar molt, but die during this process. Such larvae have two sets of mouth parts and, in some cases, two sets of anterior spiracles and/or two cuticles. Of those mutant animals that do survive the molt, approximately half stop moving during the first day of the third instar, becoming extended and stiff in an apparent attempt to pupariate. They survive in this immobile state for 2-3 days, after which patches of necrotic cells form throughout the animal. Most of the remaining mutant third instar larvae become stationary over the next few days, while some stop eating and shrink in size until they finally die. Some of the mutants pupariate normally, although 1-5 days later than control animals, and then die as prepupae. A few rigk07917/Df(2R)exu1 animals (but no rigk07917/rigk07839 animals) make it to the pupal stage before dying.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Partially rescued by
Comments

Expression of rigScer\UAS.T:Avic\GFP-ECFP driven by Scer\GAL4da.PU partially rescues lethality in rigC063/rigk07917 (80% viable adults) or rigk07917/rig05056 (55%) mutants; expression does not rescue lethality in rigk07917/rigk07917 mutants.

Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
Comments
Comments

Complements: blk08305. "l(2)05056" was originally reported as an allele of bl, but "l(2)05056" complements blk08305. In addition, "l(2)k07917" and "l(2)k07839" fail to complement "l(2)05056" and complement blk08305. "l(2)05056", "l(2)k07917" and "l(2)k07839" therefore constitute a lethal complementation group that is distinct from bl and this complementation group is referred to as "rig".

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (6)