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General Information
Symbol
Dmel\crolk05205
Species
D. melanogaster
Name
FlyBase ID
FBal0064729
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Insertion components
P{lacW}crolk05205
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Homozygous clones are rarely seen in the wing pouch of wing discs from 120 hour larvae (clones induced at 72 hours after egg deposition), in contrast to control clones. Homozygous mutant clones are recovered in the hinge region of these discs.

Small homozygous clones are recovered in the wing pouch in 96 hour larval wing discs (clones induced at 48 hours after egg deposition). Clonal cells with a pyknotic morphology are seen in the basal section of the wing pouch in these discs. The homozygous cells show reduced BrdU incorporation and a reduction in the number of mitotic cells compared to wild-type clones.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Enhancer of
Statement
Reference

crol[+]/crolk05205 is an enhancer of visible phenotype of Scer\GAL4en-e16E, hfpUAS.cQa

Suppressor of
Statement
Reference

crol[+]/crolk05205 is a suppressor of visible | dominant phenotype of gcmPyx

Phenotype Manifest In
Suppressed by
Statement
Reference
Enhancer of
Statement
Reference

crol[+]/crolk05205 is an enhancer of wing phenotype of Scer\GAL4en-e16E, hfpUAS.cQa

Suppressor of
Statement
Reference

crol[+]/crolk05205 is a suppressor of chaeta | supernumerary phenotype of gcmPyx

crol[+]/crolk05205 is a suppressor of eye phenotype of DrefUAS.cSa

Additional Comments
Genetic Interactions
Statement
Reference

crolk05205/+ enhances the reduced wing phenotype caused by expression of pUf68Scer\UAS.cQa under the control of Scer\GAL4en-e16E in the posterior compartment.

Analysis of 120 hour larval wing discs indicates that the growth of crolk05205 clones is restored if they are induced in a arm4/+ background compared to when they are induced in an otherwise wild-type background.

Xenogenetic Interactions
Statement
Reference

Co-expression of BacA\p35Scer\UAS.cHa under the control of Scer\GAL4tub in homozygous crolk05205 clones results in more mutant cells being seen in the wing pouch of wing discs from 120 hour larvae (clones induced at 72 hours after egg deposition) compared to homozygous crolk05205 clones induced in an otherwise wild-type background.

Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (3)
Notes on Origin
Discoverer
Comments
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
l(2)04418k05205
Name Synonyms
Secondary FlyBase IDs
    References (7)