FlyBase Allele Report: Dmel\chic[k13321]

General Information

Symbol

Dmel\chic^k13321

Species

D. melanogaster

Name

FlyBase ID

FBal0064928

Feature type

allele

Associated gene

Dmel\chic

Associated Insertion(s)

P{lacW}chic^k13321

Carried in Construct

Also Known As

l(2)k13321

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(BDGP Project Members, 1994-1999)

Progenitor genotype

Associated Insertion(s)

P{lacW}chic^k13321

Cytology

Description

P{lacW} insertion in intron 3 about 200bp distal from exon 3.

(Schnorr et al., 2001)

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2L:5,979,234..5,979,234 [+]

(Schnorr et al., 2001, Bloomington Drosophila Stock Center, 2000.5.18, Spradling et al., 1999, BDGP Project Members, 1994-1999)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

fertile

(Bloomington Drosophila Stock Center, 2000.5.18)

lethal

(Schnorr et al., 2001)

lethal | recessive

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

viable

(Bloomington Drosophila Stock Center, 2000.5.18)

Phenotype Manifest In

border follicle cell (with chic⁰¹³²⁰)

(Geisbrecht and Montell, 2004)

Detailed Description

Statement

Reference

8% of chic⁰¹³²⁰/chic^k13321 egg chambers have border follicle cell migration defects.

(Geisbrecht and Montell, 2004)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

chic[+]/chic^k13321 is an enhancer of visible | heat sensitive phenotype of peb¹

(Wilk et al., 2004)

Phenotype Manifest In

Enhanced by

Statement

Reference

chic⁰¹³²⁰/chic^k13321 has border follicle cell phenotype, enhanceable by Diap1^21-2s/th[+]

(Geisbrecht and Montell, 2004)

chic⁰¹³²⁰/chic^k13321 has border follicle cell phenotype, enhanceable by Diap1⁵/th[+]

(Geisbrecht and Montell, 2004)

Enhancer of

Statement

Reference

chic[+]/chic^k13321 is an enhancer of eye | heat sensitive phenotype of peb¹

(Wilk et al., 2004)

chic[+]/chic^k13321 is an enhancer of dorsal appendage phenotype of Ras85D^ix12a

(Schnorr et al., 2001)

NOT Enhancer of

Statement

Reference

chic[+]/chic^k13321 is a non-enhancer of border follicle cell phenotype of Pvf1^UAS.cMa, Scer\GAL4^slbo.2.6

(McDonald et al., 2003)

chic[+]/chic^k13321 is a non-enhancer of phenotype of ct^db7

(Jackson and Berg, 1999)

chic[+]/chic^k13321 is a non-enhancer of phenotype of ct^L188

(Jackson and Berg, 1999)

chic[+]/chic^k13321 is a non-enhancer of phenotype of ct^C145

(Jackson and Berg, 1999)

chic^k13321 is a non-enhancer of phenotype of ct^C145

(Jackson and Berg, 1999)

Additional Comments

Genetic Interactions

Statement

Reference

80% of chic⁰¹³²⁰/chic^k13321 ; th⁵/+ egg chambers have border follicle cell migration defects. 51% of chic⁰¹³²⁰/chic^k13321 ; th^21-2s/+ egg chambers have border follicle cell migration defects. In some egg chambers, the border follicle cells migrate to the side of the egg chamber instead of through the middle of the nurse cells, a phenotype that is never seen in wild-type egg chambers.

(Geisbrecht and Montell, 2004)

Weak dominant enhancer of the Ras85D^ix12a eggshell phenotype; 41-50% of dorsal appendages are wild type.

(Schnorr et al., 2001)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

chic^k02707

(BDGP Project Members, 1994-1999)

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

11087

y¹ w^67c23; P{lacW}chic^k13321

Kyoto

102869

y¹ w^67c23 ; P{lacW}chic^k13321 / CyO

Notes on Origin

Discoverer

I. Kiss.

(BDGP Project Members, 1994-1999)

Comments

"Phenotypic class: viable" was stated as revision. "Phenotypic class: fertile" was stated as revision. The stock is homozygous for the chic^k13321 second chromosome.

(Bloomington Drosophila Stock Center, 2000.5.18)

Complements: eIF-4a⁰²⁴³⁹. Complements: lid¹⁰⁴²⁴. Complements: eIF-4a^k07120.

(BDGP Project Members, 1994-1999)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

chi^k13321

chic¹³³²¹

(Geisbrecht and Montell, 2004)

chic^k13321

l(2)k13321

(Schnorr et al., 2001, Spradling et al., 1999)

Name Synonyms

Secondary FlyBase IDs

References (9)

Report Sections

Open Close