FlyBase Allele Report: Scer\GAL4[Dll-em212]

General Information

Symbol

Scer\GAL4^Dll-em212

Species

S. cerevisiae

Name

FlyBase ID

FBal0065172

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

P{GawB}Dll^em212

Carried in Construct

Also Known As

Dll-GAL4, Dll^EM212-Gal4, em212, Dll²¹²-Gal4

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Gorfinkiel et al., 1997)

Progenitor genotype

Associated Insertion(s)

P{GawB}Dll^em212

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{GawB}

enhancer trap

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

third instar larval stage

male genital disc | restricted

(Gorfinkiel et al., 1999)

female genital disc | restricted

(Gorfinkiel et al., 1999)

leg disc | distal

(Ruiz-Losada et al., 2021)

pupal stage

tarsal segment

(Martin et al., 2021)

Additional Information

Statement

Reference

ScerGAL4^Dll-em212 drives expression in developing tarsal segments.

(Martin et al., 2021)

ScerGAL4^Dll-em212 drives expression in the distal region of leg discs.

(Ruiz-Losada et al., 2021)

Drives expression in distal structures postembryonically; prominently expressed in the presumptive tarsal segments in leg discs.

(FlyBase Curators, 2017)

Larval expression is observed in the genital and anal primordia of the male and female genital discs. Adult expression is observed in the vaginal plates in females, in the claspers in males, and in the anal plates of both sexes.

(Gorfinkiel et al., 1999)

Assayed in adult cuticle using y⁺ marker. Expressed in distal portions of leg, wing, and antenna; expression in femur relatively weak.

(Gorfinkiel et al., 1997)

Marker for

cercus

(Gorfinkiel et al., 1999)

female genital disc

(Gorfinkiel et al., 1999)

hypogynium

(Gorfinkiel et al., 1999)

male genital disc

(Gorfinkiel et al., 1999)

surstylus

(Gorfinkiel et al., 1999)

Reflects expression of

Dll

(Gorfinkiel et al., 1999, Gorfinkiel et al., 1997)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal planar polarity, with ds^EP-822

(Harumoto et al., 2010)

abnormal size, with Scer\GAL80^ts.αTub84B, Sp1^GD4097, Sp1^RNAi.UAS

(Estella and Mann, 2010)

increased cell death, with RYBP^UAS.cBa

(González and Busturia, 2009)

visible | adult stage, with btd^RNAi.UAS

(Blom-Dahl et al., 2020)

visible | adult stage, with btd^UAS.cBa

(Blom-Dahl et al., 2020)

visible | adult stage, with btd^{ΔBTD-box.UAS}

(Blom-Dahl et al., 2020)

visible | adult stage, with Sp1^UAS.cBa

(Blom-Dahl et al., 2020)

visible | adult stage, with Sp1^{ΔBTD-box.UAS}

(Blom-Dahl et al., 2020)

Phenotype Manifest In

antenna, with Sp1^UAS.cSa

(Córdoba et al., 2016)

antenna, with tgo^RNAi.UAS.cAa

(Adachi-Yamada et al., 2005)

antennal disc | third instar larval stage, with RYBP^UAS.cBa

(González and Busturia, 2009)

double row of wing sensilla, with wg^RNAi.UAS

(Inaki et al., 2002)

femur | somatic clone - Minute background, with btd^XG

(Estella and Mann, 2010)

leg, with CG34166^KK110618

(Córdoba et al., 2016)

leg, with DnaJ-1^GD7025

(Córdoba et al., 2016)

leg, with Pepck1^GD9451

(Córdoba et al., 2016)

leg, with tgo^RNAi.UAS.cTa

(Tajiri et al., 2007)

leg | adult stage, with btd^RNAi.UAS

(Blom-Dahl et al., 2020)

leg | adult stage, with btd^UAS.cBa

(Blom-Dahl et al., 2020)

leg | adult stage, with btd^{ΔBTD-box.UAS}

(Blom-Dahl et al., 2020)

leg | adult stage, with Sp1^UAS.cBa

(Blom-Dahl et al., 2020)

leg | adult stage, with Sp1^{ΔBTD-box.UAS}

(Blom-Dahl et al., 2020)

leg | distal, with Scer\GAL80^ts.αTub84B, Sp1^GD4097, Sp1^RNAi.UAS

(Estella and Mann, 2010)

leg | ectopic, with tgo^RNAi.UAS.cAa

(Adachi-Yamada et al., 2005)

leg disc | P-stage, with Arp2^JF02785

(Martin et al., 2021)

leg disc | P-stage, with Arpc3A^JF02370

(Martin et al., 2021)

leg disc | P-stage, with Arpc5^JF03147

(Martin et al., 2021)

leg disc | third instar larval stage, with RYBP^UAS.cBa

(González and Busturia, 2009)

mesothoracic tibial preapical bristle | increased number, with fd96Cb^UAS.cRa

(Ruiz-Losada et al., 2021)

microchaeta & tarsal segment 5, with pxb^UAS.cIa

(Inaki et al., 2002)

microchaeta & tarsal segment 5, with wg^RNAi.UAS

(Inaki et al., 2002)

segment of leg, with CG34166^KK110618

(Córdoba et al., 2016)

segment of leg, with DnaJ-1^GD7025

(Córdoba et al., 2016)

segment of leg, with Pepck1^GD9451

(Córdoba et al., 2016)

segment of leg | adult stage, with btd^RNAi.UAS

(Blom-Dahl et al., 2020)

segment of leg | adult stage, with btd^UAS.cBa

(Blom-Dahl et al., 2020)

segment of leg | adult stage, with btd^{ΔBTD-box.UAS}

(Blom-Dahl et al., 2020)

segment of leg | adult stage, with Sp1^UAS.cBa

(Blom-Dahl et al., 2020)

segment of leg | adult stage, with Sp1^{ΔBTD-box.UAS}

(Blom-Dahl et al., 2020)

sex comb tooth | decreased number, with fd96Ca^HMC04655

(Ruiz-Losada et al., 2021)

sex comb tooth | decreased number, with fd96Ca^UAS.cRa

(Ruiz-Losada et al., 2021)

tarsal segment 4, with tgo^RNAi.UAS.cTa

(Tajiri et al., 2007)

tarsal segment 5, with tgo^RNAi.UAS.cTa

(Tajiri et al., 2007)

tarsal segment, with Dll^UAS.cGa

(Gorfinkiel et al., 1997)

tibia | somatic clone - Minute background, with btd^XG

(Estella and Mann, 2010)

triple row of wing sensilla, with wg^RNAi.UAS

(Inaki et al., 2002)

unguis, with dpp^RNAi.UAS.cIa

(Inaki et al., 2002)

unguis | absent, with fd96Cb^UAS.cRa

(Ruiz-Losada et al., 2021)

wing | distal | posterior, with wg^RNAi.UAS

(Inaki et al., 2002)

wing hair, with ds^EP-822

(Harumoto et al., 2010)

wing vein | distal, with dpp^RNAi.UAS.cIa

(Inaki et al., 2002)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhanced by

Statement

Reference

Scer\GAL4^Dll-em212, fd96Ca^HMC04655 has sex comb tooth | decreased number phenotype, enhanceable by Scer\GAL4^Dll-em212/fd96Cb^JF02325

(Ruiz-Losada et al., 2021)

Scer\GAL4^Dll-em212, fd96Cb^UAS.cRa has unguis | absent phenotype, enhanceable by Scer\GAL4^Dll-em212/fd96Ca^UAS.cRa

(Ruiz-Losada et al., 2021)

NOT Enhanced by

Statement

Reference

Scer\GAL4^Dll-em212, fd96Ca^UAS.cRa has sex comb tooth | decreased number phenotype, non-enhanceable by Scer\GAL4^Dll-em212/fd96Cb^UAS.cRa

(Ruiz-Losada et al., 2021)

Scer\GAL4^Dll-em212, fd96Cb^UAS.cRa has mesothoracic tibial preapical bristle | increased number phenotype, non-enhanceable by Scer\GAL4^Dll-em212/fd96Ca^UAS.cRa

(Ruiz-Losada et al., 2021)

Enhancer of

Statement

Reference

Scer\GAL4^Dll-em212/fd96Cb^JF02325 is an enhancer of sex comb tooth | decreased number phenotype of Scer\GAL4^Dll-em212, fd96Ca^HMC04655

(Ruiz-Losada et al., 2021)

Scer\GAL4^Dll-em212/fd96Ca^UAS.cRa is an enhancer of unguis | absent phenotype of Scer\GAL4^Dll-em212, fd96Cb^UAS.cRa

(Ruiz-Losada et al., 2021)

NOT Enhancer of

Statement

Reference

Scer\GAL4^Dll-em212/fd96Cb^UAS.cRa is a non-enhancer of sex comb tooth | decreased number phenotype of Scer\GAL4^Dll-em212, fd96Ca^UAS.cRa

(Ruiz-Losada et al., 2021)

Scer\GAL4^Dll-em212/fd96Ca^UAS.cRa is a non-enhancer of mesothoracic tibial preapical bristle | increased number phenotype of Scer\GAL4^Dll-em212, fd96Cb^UAS.cRa

(Ruiz-Losada et al., 2021)

Suppressor of

Statement

Reference

Scer\GAL4^Dll-em212/BacA\p35^UAS.cHa is a suppressor of leg disc | somatic clone phenotype of BacA\p35^UAS.cHa

(Estella and Mann, 2010)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Scer\GAL4^Dll-em212/Sp1^UAS.cSa rescues Df(1)btd-Sp1

(Estella and Mann, 2010)

Scer\GAL4^Dll-em212/Dll^UAS.cGa rescues Dll¹⁴

(Gorfinkiel et al., 1997)

Scer\GAL4^Dll-em212/Dll^UAS.cGa rescues Dll^em212/Df(2R)Dll-MP

(Gorfinkiel et al., 1997)

Scer\GAL4^Dll-em212/Dll^UAS.cGa rescues Dll³

(Gorfinkiel et al., 1997)

Partially rescues

Scer\GAL4^Dll-em212/Sp1^L.UAS partially rescues Df(1)btd-Sp1

(Estella and Mann, 2010)

Fails to rescue

Scer\GAL4^Dll-em212/btd^UAS.cSa fails to rescue Df(1)btd-Sp1

(Estella and Mann, 2010)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

GAL4^Dll-em212

Scer\GAL4^Dll-em212

Name Synonyms

Secondary FlyBase IDs

References (27)

Report Sections

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