Flies overexpressing wgScer\UAS.cKa under the control of Scer\GAL4Hml.Δ in the hemocytes develop normally, with no obvious defects after they hatch. Expression of hhScer\UAS.cIa does not protect against infection with group B streptococcus.
Ectopic expression of wgScer\UAS.cKa in males under the control of Scer\GAL4dsx-GAL4 results in the formation of a female-like adult abdominal segment 7 cuticle. The mutant males develop excess tissue posterior to the A6 tergite. This excess tissue is sclerotised and pigmented, suggesting that it adopts anterior cuticle fate. Ventral histoblasts are also transformed generating an A7 sternite. Additionally, ectopic wgScer\UAS.cKa expression results in partial transformation of the male A6 sternite toward more anterior identity. Compared with wild-type males, the A6 sternite of males expressing wgScer\UAS.cKa under the control of Scer\GAL4dsx-GAL4 is more rectangular and develop supernumerary bristles. The transformed A7 cuticle of the mutant males is narrower than more anterior segments and devoid of bristles.
Expression of wgScer\UAS.cKa in alternating embryonic segements, driven by Scer\GAL4h-1J3, results in the formation of ectopic naked cuticle.
When expression is driven by Scer\GAL4da.G32 a completely naked embryonic cuticle results. When expression is driven in the eye with Scer\GAL4GMR.PF, a glassy reduced eye results. When expression is driven in the eye with Scer\GAL4GMR.PF, the eye becomes slightly roughened.