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General Information
Symbol
Dmel\nej1
Species
D. melanogaster
Name
FlyBase ID
FBal0065728
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Most nej1 hemizygotes develop to the end of embryogenesis and are phenotypically wild type. Approximately 13% of the embryos have head defects and 4.5% have fusions of the segmental denticle belts, primarily between the denticle belts of the fourth and the fifth abdominal segments.

    Embryos derived from homozygous females show loss of the amnioserosa and other derivatives of the dorsal ectoderm.

    In mutant embryos derived from mutant female germlines the midgut phenotypes range from mild to severe.

    Fertile eggs are produced from germ line clones. Paternally rescued eggs exhibit narrowing of the head and thorax regions and lack epidermal structures in the dorsal and ventral regions.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Enhancer of
    Statement
    Reference
    Phenotype Manifest In
    Additional Comments
    Genetic Interactions
    Statement
    Reference

    Fifteen percent (73 of 487) of nej1 hemizysgous; Df(3R)A4-4L8 homozygous embryos have fusions of the segmental denticle belts. These fusions occur between the second and the third, the third and the fourth, or the fourth and the fifth abdominal segments. 24.2% (118 of 487) of these embryos have head defects. This percentage suggests an additive effect on embryonic head development.

    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (1)
    Reported As
    Symbol Synonym
    Name Synonyms
    Secondary FlyBase IDs
      References (10)