FB2025_01 , released February 20, 2025
Allele: Ecol\lacZDad-P1883
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General Information
Symbol
Ecol\lacZDad-P1883
Species
E. coli
Name
FlyBase ID
FBal0065787
Feature type
allele
Associated gene
Ecol\lacZ
Associated Insertion(s)
P{lacZ}DadP1883
Carried in Construct
Also Known As
dad-lacZ, DadP1883, P{dad-lacZ}
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Tsuneizumi et al., 1997)
Progenitor genotype
Associated Insertion(s)
P{lacZ}DadP1883
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{lacZ}
Encoded product / tool
lacZ
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      embryonic stage
      (Tsuneizumi et al., 1997)
      third instar larval stage
      wing disc | restricted
      (Tsuneizumi et al., 1997)
      eye disc | restricted
      (Firth et al., 2010)
      wandering third instar larval stage
      anterior-posterior compartment boundary of the wing disc
      (Tsuneizumi et al., 1997)
      oogenesis
      female germline stem cell
      (Song et al., 2004)
      cystoblast | subset
      (Song et al., 2004)
      oogenesis stage S8 -- S10
      centripetal follicle cell
      (Muzzopappa and Wappner, 2005)
      oogenesis stage S10
      border follicle cell
      (Muzzopappa and Wappner, 2005)
      spermatogenesis
      male germline stem cell
      (Kawase et al., 2004)
      primary gonial cell
      (Kawase et al., 2004)
      Additional Information
      Statement
      Reference

      The reporter is active from 4-5 cell diameters anterior of the morphogenetic furrow backwards to the posterior of the disc. Reporter expression extends slightly more anteriorly at the poles of the disc than at the equator.

      (Firth et al., 2010)

      EcollacZDad-P1883 is first detected at oogenesis stage S8 in terminal anterior follicle cells that migrate towards the oocyte. By oogenesis stage S10, EcollacZDad-P1883 expression is detected in centripetal and border cells located at the anterior border of the oocyte, as well as in stretched cells which surround the nurse cells.

      (Muzzopappa and Wappner, 2005)

      EcollacZDad-P1883 is expressed at the A/P boundary of the wing disc, in a stripe overlapping but broader than that of dpp.

      (Tsuneizumi et al., 1997)

      Expression pattern of this reporter construct during embryonic and imaginal development resembles that of dpp.

      (Tsuneizumi et al., 1997)
       
      Marker for
      cystoblast
      (Song et al., 2004)
      male germline stem cell
      (Kawase et al., 2004)
      primary gonial cell
      (Kawase et al., 2004)
      Reflects expression of
      Dad
      (Firth et al., 2010, Muzzopappa and Wappner, 2005, Kawase et al., 2004, Song et al., 2004, Tsuneizumi et al., 1997)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      DadP1883
      (Torres-Vazquez et al., 2001, Torres-Vazquez et al., 2000)
      Ecol\lacZDad-P1883
      P1883
      (Minami et al., 1999)
      lacZDad-P1883
      Name Synonyms
      Secondary FlyBase IDs
        References (42)