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General Information
Symbol
Dmel\Rap1E8
Species
D. melanogaster
Name
FlyBase ID
FBal0065999
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
point mutation
Nucleotide change:

G1860755A

Amino acid change:

V153M | Rap1-PA; V153M | Rap1-PB; V153M | Rap1-PC

Reported amino acid change:

V153M

Comment:

site of nucleic acid difference inferred by FlyBase based on stated amino acid change

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Amino acid replacement: V153M.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Homozygotes exhibit rough eyes, some facets are missing R7 cells and numbers of outer R cells.

Roughened external eye morphology, internally most facets are missing R7 and some are missing outer cells.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhanced by
Statement
Reference

Rap1E8 has eye photoreceptor cell phenotype, enhanceable by fafBX3

Rap1E8 has eye photoreceptor cell phenotype, enhanceable by fafFO8

Additional Comments
Genetic Interactions
Statement
Reference

Enhances the fafBX3/fafFO8 eye phenotype: facets are often missing the R7 receptor cell.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

Mutation is not a simple hypermorph or hypomorph. The protein does provide some wild type activity and also antagonises the wild-type function in some manner.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
E(faf)E8
RE8
Rap1E8
Rap1V153M
Name Synonyms
Secondary FlyBase IDs
    References (2)