Allele Scer\GAL4^c747

General Information
Symbol	Scer\GAL4^c747	Species	S. cerevisiae
Name		FlyBase ID	FBal0066070
Feature type	allele	Associated gene	Scer\GAL4
Also Known As	C747

Allele class
Mutagen	P-element activity
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class
Mutagen	P-element activity (Yang et al., 1995, Tettamanti et al., 1997)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Caused by insertion	P{GawB}c747 (Yang et al., 1995, Connolly et al., 1996, Tettamanti et al., 1997, Reeve et al., 2005, Kitamoto, 2002, Rodan et al., 2002, Presente et al., 2004, Astle et al., 2003, DeZazzo et al., 2000, Broughton et al., 2004, McGuire et al., 2003, Waddell et al., 2000, Zars et al., 2000, Zars et al., 2000, Suh et al., 2004, Cheng et al., 2001, Dubnau et al., 2001, Kraft et al., 1998, McGuire et al., 2001, Manseau et al., 1997, Pitman et al., 2006, Joiner et al., 2006, Grammenoudi et al., 2006, Lu et al., 2007, Kang et al., 2011, Chen et al., 2012, Tzortzopoulos and Skoulakis, 2007, Keleman et al., 2007, Horiuchi et al., 2008, Bolduc et al., 2008, Krashes et al., 2007, Donlea et al., 2009, Schwaerzel et al., 2002, Bates et al., 2010, Liu et al., 2007, Armstrong et al., 1998, Moressis et al., 2009, Hekmat-Scafe et al., 2010, Tamura et al., 2010, Buchanan and Davis, 2010, Ferris et al., 2006, Gouzi et al., 2011, Majumdar et al., 2012, Crocker et al., 2010, Aso et al., 2009, Pauls et al., 2010, Mershin et al., 2004, Kosmidis et al., 2010, Papanikolopoulou et al., 2010, Sakai and Kitamoto, 2006, Chen et al., 2008)
Cytology
Phenotypic Data
Phenotypic Class
	behavior defective \| heat sensitive, with shi^1.Scer\UAS (Pitman et al., 2006) courtship behavior defective, with shi^1.Scer\UAS (Broughton et al., 2004) courtship behavior defective \| male \| heat sensitive, with shi^1.Scer\UAS (Sakai and Kitamoto, 2006) learning defective, with Btau\MAPT^Scer\UAS.cKa (Mershin et al., 2004) learning defective, with drk^{dsRNA.Sym.Scer\UAS} (Moressis et al., 2009) learning defective, with Gαs^{Q215L.Scer\UAS} (Connolly et al., 1996) learning defective, with Hsap\MAPT^Scer\UAS.cWa (Mershin et al., 2004) learning defective, with Ras85D^V12.Scer\UAS (Moressis et al., 2009) learning defective, with Rdl^{dsRNA.4-5.Scer\UAS} (Liu et al., 2007) learning defective, with Rdl^{dsRNA.8-10.Scer\UAS} (Liu et al., 2007) learning defective, with Rdl^Scer\UAS.cLa (Liu et al., 2007) learning defective, with tau^Scer\UAS.cMa (Mershin et al., 2004) learning defective \| adult stage \| heat sensitive, with Rdl^Scer\UAS.cLa, Scer\GAL80^ts.αTub84B (Liu et al., 2007) learning defective \| heat sensitive, with shi^1.Scer\UAS (Dubnau et al., 2001) lethal, with Adf1^Scer\UAS.cDa (DeZazzo et al., 2000) locomotor behavior defective, with shi^1.Scer\UAS (Broughton et al., 2004) locomotor behavior defective \| adult stage \| heat sensitive, with shi^1.Scer\UAS (Sakai and Kitamoto, 2006) memory defective, with Bper\ptxA^act.Scer\UAS (Ferris et al., 2006) memory defective, with Btau\MAPT^Scer\UAS.cKa (Mershin et al., 2004) memory defective, with Fmr1^{dsRNA.280.Scer\UAS} (Bolduc et al., 2008) memory defective, with Fmr1^{dsRNA.500.Scer\UAS} (Bolduc et al., 2008) memory defective, with Hsap\MAPT^Scer\UAS.cWa (Mershin et al., 2004) memory defective, with N^{dsRNA.P.Scer\UAS} (Presente et al., 2004) memory defective, with tau^Scer\UAS.cMa (Mershin et al., 2004) memory defective \| heat sensitive, with shi^1.Scer\UAS (Dubnau et al., 2001, Schwaerzel et al., 2002) neuroanatomy defective, with Fmr1^Scer\UAS.cZa (Reeve et al., 2005) neurophysiology defective \| heat sensitive, with shi^1.Scer\UAS (Dubnau et al., 2001) sleep defective, with Pka-R1^{BDK.Scer\UAS.T:Ivir\HA1} (Crocker et al., 2010) smell perception defective \| heat sensitive, with shi^1.Scer\UAS (McGuire et al., 2001) song defective, with eag^{Δ932.Scer\UAS} (Broughton et al., 2004) song defective, with shi^1.Scer\UAS (Broughton et al., 2004) temperature response defective \| adult stage, with Cyp6a17^{dsRNA.Scer\UAS.WIZ} (Kang et al., 2011) viable, with Rdl^Scer\UAS.cLa (Liu et al., 2007)
Phenotype Manifest In
	adult mushroom body, with Fmr1^Scer\UAS.cZa (Reeve et al., 2005) adult mushroom body, with shi^1.Scer\UAS (Dubnau et al., 2001)
Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement Reference Fmr1^Scer\UAS.cZa, Scer\GAL4^c747 has neuroanatomy defective phenotype, suppressible by chic^Scer\UAS.cCa, Scer\GAL4^c747 (Reeve et al., 2005, Reeve et al., 2005) Fmr1^Scer\UAS.cZa, Scer\GAL4^c747 has neuroanatomy defective phenotype, suppressible by chic^Scer\UAS.cCa/Scer\GAL4^P2.4.Pdf (Reeve et al., 2005)
Suppressor of
Statement Reference chic^Scer\UAS.cCa, Scer\GAL4^c747 is a suppressor of neuroanatomy defective phenotype of Fmr1^Scer\UAS.cZa, Scer\GAL4^c747 (Reeve et al., 2005, Reeve et al., 2005) Scer\GAL4^c747/Ncc69^GD14863 is a suppressor \| partially of paralytic \| recessive phenotype of kcc^DHS1 (Hekmat-Scafe et al., 2010) Scer\GAL4^c747/phl^fl.Scer\UAS is a suppressor of learning defective phenotype of drk^e0A (Moressis et al., 2009) Scer\GAL4^c747/phl^{Scer\UAS.F179} is a suppressor of learning defective phenotype of drk^e0A (Moressis et al., 2009) Scer\GAL4^c747/phl^{Scer\UAS.F179} is a suppressor of learning defective phenotype of drk^ΔP24 (Moressis et al., 2009) Scer\GAL4^c747/Ras85D^{V12.S35.Scer\UAS} is a suppressor of learning defective phenotype of drk^ΔP24 (Moressis et al., 2009) Scer\GAL4^c747/Rdl^{dsRNA.8-10.Scer\UAS} is a suppressor \| partially of paralytic \| recessive phenotype of kcc^DHS1 (Hekmat-Scafe et al., 2010)
NOT Suppressor of
Statement Reference Scer\GAL4^c747, phl^{Scer\UAS.F179}, Scer\GAL80^ts.αTub84B is a non-suppressor of learning defective phenotype of drk^ΔP24 (Moressis et al., 2009) Scer\GAL4^c747, Scer\GAL80^ts.αTub84B, Ras85D^{V12.S35.Scer\UAS} is a non-suppressor of learning defective phenotype of drk^ΔP24 (Moressis et al., 2009) Scer\GAL4^c747/Alk^{EC.Scer\UAS.T:Hsap\MYC} is a non-suppressor of learning defective \| adult stage phenotype of Nf1^E1/Nf1^E2 (Gouzi et al., 2011) Scer\GAL4^c747/Alk^GD42 is a non-suppressor of learning defective \| adult stage phenotype of Nf1^E1/Nf1^E2 (Gouzi et al., 2011) Scer\GAL4^c747/phl^fl.Scer\UAS is a non-suppressor of memory defective phenotype of drk^ΔP24 (Moressis et al., 2009) Scer\GAL4^c747/phl^{Scer\UAS.F179} is a non-suppressor of memory defective phenotype of drk^ΔP24 (Moressis et al., 2009)
Phenotype Manifest In
Suppressed by
Statement Reference Fmr1^Scer\UAS.cZa, Scer\GAL4^c747 has adult mushroom body phenotype, suppressible by chic^Scer\UAS.cCa, Scer\GAL4^c747 (Reeve et al., 2005, Reeve et al., 2005) Fmr1^Scer\UAS.cZa, Scer\GAL4^c747 has LNv neuron phenotype, suppressible by chic^Scer\UAS.cCa/Scer\GAL4^P2.4.Pdf (Reeve et al., 2005)
Suppressor of
Statement Reference chic^Scer\UAS.cCa, Scer\GAL4^c747 is a suppressor of adult mushroom body phenotype of Fmr1^Scer\UAS.cZa, Scer\GAL4^c747 (Reeve et al., 2005, Reeve et al., 2005)
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Rescues	Scer\GAL4^c747/Nf1^Scer\UAS.cBa rescues Nf1^c00617 (Buchanan and Davis, 2010) Scer\GAL4^c747/orb2^A.Scer\UAS rescues orb2^ΔQ/orb2^Δ (Keleman et al., 2007) Scer\GAL4^c747/orb2^B.Scer\UAS rescues orb2^ΔQ/orb2^Δ (Keleman et al., 2007) Scer\GAL4^c747/Pka-C1^{Scer\UAS.T:Zzzz\FLAG} rescues Pka-C1^B3 (Horiuchi et al., 2008) Scer\GAL4^c747/rut^Scer\UAS.cZa rescues rut²⁰⁸⁰ (Zars et al., 2000, McGuire et al., 2003, Zars et al., 2000) Scer\GAL4^c747/spoon^Scer\UAS.cYa rescues spoon^P1 (Lu et al., 2007)
Partially rescues	Scer\GAL4^c747/kcc^Scer\UAS.cHb partially rescues kcc^DHS1 (Hekmat-Scafe et al., 2010)
Fails to rescue	Scer\GAL4^c747, Nf1^Scer\UAS.cWa, Scer\GAL80^ts.αTub84B fails to rescue Nf1^E1/Nf1^E2 (Gouzi et al., 2011) Scer\GAL4^c747/amn^Scer\UAS.cWa fails to rescue amn^X8 (Waddell et al., 2000) Scer\GAL4^c747/Hr78^Scer\UAS.Fa fails to rescue Hr78³/Hr78² (Astle et al., 2003) Scer\GAL80^Mef2.PT, Scer\GAL4^c747, Nf1^Scer\UAS.cBa fails to rescue Nf1^c00617 (Buchanan and Davis, 2010)
Comments
Stocks ( 2 )
Bloomington	6494 w^*; P{GawB}c747
Kyoto	108808 w^*; P{GawB}c747
Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym	C747 (Kitamoto, 2002, DeZazzo et al., 2000) GAL4^c747 GAL4^C747 GAL4^c772 Scer\GAL4^c747 Scer\GAL4^c772
Name Synonym
Secondary FlyBase IDs
	FBal0048790 FBal0058805 FBal0155845
References ( 51 )

Generate a list of	All references relating to this allele ( 51 )

List References by type	Research paper ( 48 ) Supplementary material ( 1 ) Review ( 1 ) Letter ( 1 )
Recent research papers ( 4 )
	Chen et al., 2012, Science 335(6069): 678--685 Visualizing long-term memory formation in two neurons of the Drosophila brain. [FBrf0217453] Majumdar et al., 2012, Cell 148(3): 515--529 Critical Role of Amyloid-like Oligomers of Drosophila Orb2 in the Persistence of Memory. [FBrf0217407] Gouzi et al., 2011, PLoS Genet. 7(9): e1002281 The receptor tyrosine kinase alk controls neurofibromin functions in Drosophila growth and learning. [FBrf0216258] Kang et al., 2011, PLoS ONE 6(12): e29800 Novel Cytochrome P450, cyp6a17, Is Required for Temperature Preference Behavior in Drosophila. [FBrf0217065] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...

Allele Scer\GAL4c747

Allele Scer\GAL4^c747